Targeting bacterial quorum sensing shows promise in improving intestinal barrier function following burn‑site infection

Targeting bacterial quorum sensing shows promise in improving intestinal barrier function following burn‑site infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2019.10071
P932PMC publication ID6472113
P698PubMed publication ID30896813

P2093author name stringRichard A Hodin
Laurence G Rahme
Mohammad Hadi Gharedaghi
Marianna Almpani
Mehran Najibi
Fatemeh Adiliaghdam
P2860cites workAnalysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky GutQ28081848
Intestinal barrier function: molecular regulation and disease pathogenesisQ28250081
Common Virulence Factors for Bacterial Pathogenicity in Plants and AnimalsQ28292772
The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI or the production of N-acyl-L-homoserine lactonesQ28493075
Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicityQ28542505
Circulating mitochondrial DAMPs cause inflammatory responses to injuryQ29614470
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in miceQ29615055
Inhibitors of pathogen intercellular signals as selective anti-infective compoundsQ33302936
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammationQ34408108
Burns in low- and middle-income countries: a review of available literature on descriptive epidemiology, risk factors, treatment, and preventionQ34538554
Claudins and the modulation of tight junction permeabilityQ34650517
Prediction of multiple infections after severe burn trauma: a prospective cohort studyQ34825134
Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanismsQ35007624
Burn Injury Alters the Intestinal Microbiome and Increases Gut Permeability and Bacterial TranslocationQ35685953
Burn-induced gut barrier injury is attenuated by phosphodiesterase inhibition: effects on tight junction structural proteinsQ36241916
A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharideQ37287436
Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfRQ37291373
Cytokine regulation of tight junctionsQ37308566
Postnatal regulation of MAMDC4 in the porcine intestinal epithelium is influenced by bacterial colonizationQ37419012
Potential of Lactobacillus plantarum CCFM639 in Protecting against Aluminum Toxicity Mediated by Intestinal Barrier Function and Oxidative Stress.Q37535417
Burns: Pathophysiology of Systemic Complications and Current ManagementQ37558018
Gut to Brain Dysbiosis: Mechanisms Linking Western Diet Consumption, the Microbiome, and Cognitive Impairment.Q37611785
Intestinal antimicrobial peptides during homeostasis, infection, and diseaseQ38054086
Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tipQ38271846
Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic ToleranceQ38852941
Regulation of intestinal permeability: The role of proteasesQ39239228
In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor TreatmentQ40179538
Assessment of the Intestinal Barrier with Five Different Permeability Tests in Healthy C57BL/6J and BALB/cJ MiceQ40371820
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanismsQ40614064
Effects of Mesalamine Treatment on Gut Barrier Integrity After Burn InjuryQ41036330
Increased intestinal permeability associated with infection in burn patientsQ41390988
Burn-injury affects gut-associated lymphoid tissues derived CD4+ T cellsQ41822917
Increased gut permeability early after burns correlates with the extent of burn injuryQ43462274
Differential pathophysiology of bacterial translocation after thermal injury and sepsisQ44014128
TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activationQ44758263
PSEUDOMONAS BURN WOUND SEPSIS. II HEMATOGENOUS INFECTION AT THE JUNCTION OF THE BURN WOUND AND THE UNBURNED HYPODERMIS.Q44774788
Exacerbation of intestinal permeability in rats after a two-hit injury: burn and Enterococcus faecalis infectionQ45217244
Pharmacological Inhibition of the Pseudomonas aeruginosa MvfR Quorum-Sensing System Interferes with Biofilm Formation and Potentiates Antibiotic-Mediated Biofilm DisruptionQ48657210
Systemic inflammatory responses and multiple organ dysfunction syndrome following skin burn wound and Pseudomonas aeruginosa infection in mice.Q50960262
Risk factors for nosocomial infection and mortality in burn patients: 10 years of experience at a university hospital.Q50994040
Segmental expression of claudin proteins correlates with tight junction barrier properties in rat intestineQ56972159
A standard animal burnQ72220242
Additive effects of thermal injury and infection on gut permeabilityQ72296273
PSEUDOMONAS BURN WOUND SEPSIS. I PATHOGENESIS OF EXPERIMENTAL PSEUDOMONAS BURN WOUND SEPSISQ76846032
Cutaneous burn increases apoptosis in the gut epithelium of miceQ77895098
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectquorum sensingQ905754
P304page(s)4057-4066
P577publication date2019-05-01
P1433published inMolecular Medicine ReportsQ26842180
P1476titleTargeting bacterial quorum sensing shows promise in improving intestinal barrier function following burn‑site infection
P478volume19

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