| scholarly article | Q13442814 |
| P50 | author | Manuela Sollazzo | Q57078728 |
| P2093 | author name string | Paola Bellosta | |
| Daniela Grifoni | |||
| Alice Maria Valenza | |||
| Mariateresa Allocca | |||
| Zhasmine Mirzoyan | |||
| P2860 | cites work | The Hallmarks of Cancer | Q221226 |
| Adipose Triglyceride Lipase (ATGL) Expression Is Associated with Adiposity and Tumor Stromal Proliferation in Patients with Pancreatic Ductal Adenocarcinoma. | Q51145395 | ||
| The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. | Q52100108 | ||
| Contribution of Tumor Endothelial Cells in Cancer Progression. | Q52563257 | ||
| Drosophila myc regulates cellular growth during development. | Q52573250 | ||
| A new Drosophila APC homologue associated with adhesive zones of epithelial cells. | Q52574297 | ||
| Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila. | Q52668701 | ||
| Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors. | Q52670682 | ||
| Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre. | Q52677781 | ||
| Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition! | Q52708462 | ||
| The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer. | Q52724146 | ||
| Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut. | Q52746350 | ||
| Transformed epithelia trigger non-tissue-autonomous tumor suppressor response by adipocytes via activation of Toll and Eiger/TNF signaling. | Q52766873 | ||
| Cancer in Drosophila: Imaginal Discs as a Model for Epithelial Tumor Formation. | Q52845197 | ||
| Anthocyanins Function as Anti-Inflammatory Agents in a Drosophila Model for Adipose Tissue Macrophage Infiltration. | Q54112785 | ||
| Wingless/Wnt Signaling in Intestinal Development, Homeostasis, Regeneration and Tumorigenesis: A Drosophila Perspective. | Q54206333 | ||
| Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues | Q57802347 | ||
| Cancer and comorbidity: The role of leptin in breast cancer and associated pathologies | Q58551567 | ||
| Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in | Q58697392 | ||
| Ras1 promotes cellular growth in the Drosophila wing | Q73490740 | ||
| The JNK signal transduction pathway | Q79781771 | ||
| MAP kinase pathways | Q85356338 | ||
| Evolution of mechanotransduction via YAP/TAZ in animal epithelia | Q87868743 | ||
| Extracellular vesicles and anti-cancer drug resistance | Q90024688 | ||
| Hallmarks of Cancer: The Next Generation | Q22252312 | ||
| Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded | Q24299457 | ||
| The Hippo Signaling Pathway in Development and Cancer | Q24603986 | ||
| Telomerase: The Devil Inside | Q26739948 | ||
| FlyBase portals to human disease research using Drosophila models | Q26765019 | ||
| Drosophila tools and assays for the study of human diseases | Q26765022 | ||
| Notch signaling: an emerging therapeutic target for cancer treatment | Q26784068 | ||
| MYC and metabolism on the path to cancer | Q26798086 | ||
| ATP-citrate lyase: a key player in cancer metabolism | Q26822813 | ||
| Drosophila at the intersection of infection, inflammation, and cancer | Q26827570 | ||
| The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment | Q27025661 | ||
| A drosophila model for EGFR-Ras and PI3K-dependent human glioma | Q27312887 | ||
| Drosophila Lung Cancer Models Identify Trametinib plus Statin as Candidate Therapeutic | Q27319935 | ||
| Cancer-related inflammation | Q27860907 | ||
| Metastatic colonization by circulating tumour cells | Q28076164 | ||
| The interplay between obesity and cancer: a fly view | Q28079088 | ||
| Drosophila blood cells and their role in immune responses | Q28081339 | ||
| salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines | Q28219379 | ||
| Mutations in CIC and FUBP1 contribute to human oligodendroglioma | Q28244895 | ||
| Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer | Q28269498 | ||
| Genomic instability--an evolving hallmark of cancer | Q28274009 | ||
| Crypt stem cells as the cells-of-origin of intestinal cancer | Q28304418 | ||
| Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver | Q28587974 | ||
| Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded | Q28752559 | ||
| The biology of cancer: metabolic reprogramming fuels cell growth and proliferation | Q29547301 | ||
| Molecular mechanisms and clinical applications of angiogenesis | Q29547314 | ||
| Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis | Q29615747 | ||
| The host defense of Drosophila melanogaster | Q29617555 | ||
| Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis | Q29619677 | ||
| Linking colorectal cancer to Wnt signaling | Q29619810 | ||
| The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis | Q29619851 | ||
| A renaissance for SRC | Q30014833 | ||
| Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review | Q30356126 | ||
| Regulation of protein stability by GSK3 mediated phosphorylation | Q30437017 | ||
| Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. | Q50777362 | ||
| Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport | Q36918095 | ||
| Cell polarity in development and cancer. | Q36925556 | ||
| Inflammation: a driving force speeds cancer metastasis | Q36986448 | ||
| dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth | Q37015808 | ||
| Lipid droplets and cellular lipid metabolism | Q37157015 | ||
| EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors | Q37205147 | ||
| PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1. | Q37207668 | ||
| Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases | Q37233375 | ||
| A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO | Q37274456 | ||
| Ajuba family proteins link JNK to Hippo signaling. | Q37315284 | ||
| Insulin/TOR signaling in growth and homeostasis: a view from the fly world | Q37321135 | ||
| PTEN in cancer, metabolism, and aging. | Q37331397 | ||
| scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila | Q37367551 | ||
| The diverse roles of the TNF axis in cancer progression and metastasis | Q37474735 | ||
| Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling | Q37494535 | ||
| The cancer-obesity connection: what do we know and what can we do? | Q37550530 | ||
| The Drosophila Accessory Gland as a Model for Prostate Cancer and Other Pathologies | Q37577716 | ||
| The fabulous destiny of the Drosophila heart. | Q37589258 | ||
| Prospective study of body size throughout the life-course and the incidence of endometrial cancer among premenopausal and postmenopausal women | Q37590354 | ||
| Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration | Q37602752 | ||
| Tissue remodelling through branching morphogenesis | Q37627165 | ||
| Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells. | Q37646868 | ||
| Socializing with MYC: cell competition in development and as a model for premalignant cancer | Q37670765 | ||
| Polarization of Drosophila neuroblasts during asymmetric division | Q37672289 | ||
| Systematic screen of chemotherapeutics in Drosophila stem cell tumors | Q37674308 | ||
| The pro- and anti-inflammatory properties of the cytokine interleukin-6. | Q37836084 | ||
| Excess body weight and the risk of primary liver cancer: an updated meta-analysis of prospective studies | Q37996785 | ||
| Ras-oncogenic Drosophila hindgut but not midgut cells use an inflammation-like program to disseminate to distant sites | Q38051565 | ||
| Chemical genetics of acetyl-CoA carboxylases. | Q38077441 | ||
| The Hippo pathway and human cancer. | Q38087215 | ||
| A Drosophila approach to thyroid cancer therapeutics | Q38139522 | ||
| Adipose tissue and adipocyte dysregulation | Q38153895 | ||
| The regulation and functions of MAPK pathways in Drosophila | Q38188305 | ||
| Rewiring cell polarity signaling in cancer | Q38196268 | ||
| Hippo Reprograms the Transcriptional Response to Ras Signaling. | Q42777863 | ||
| A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors. | Q42878689 | ||
| The Drosophila lymph gland as a developmental model of hematopoiesis | Q46163386 | ||
| ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. | Q46469067 | ||
| Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling | Q47070215 | ||
| Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator | Q47070726 | ||
| Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. | Q47071360 | ||
| Drosophila myc regulates organ size by inducing cell competition | Q47071644 | ||
| hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement. | Q47071857 | ||
| Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster | Q47072023 | ||
| dMyc transforms cells into super-competitors | Q47072112 | ||
| The Biology of Cancer Exosomes: Insights and New Perspectives. | Q47377575 | ||
| Non-mammalian models of multiple endocrine neoplasia type 2. | Q47724734 | ||
| Mechanobiology of YAP and TAZ in physiology and disease. | Q47738846 | ||
| Feedback amplification loop drives malignant growth in epithelial tissues | Q47741462 | ||
| Dissecting JNK signaling, one KKKinase at a time. | Q47864415 | ||
| Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes | Q48487355 | ||
| Targeting de novo lipogenesis as a novel approach in anti-cancer therapy | Q48608544 | ||
| Tumorigenic Properties of Drosophila Epithelial Cells Mutant for lethal giant larvae | Q48707500 | ||
| Failure of the PTEN/aPKC/Lgl Axis Primes Formation of Adult Brain Tumours in Drosophila | Q49478610 | ||
| Adipocyte Death and Chronic Inflammation in Obesity | Q49711844 | ||
| EGF signaling regulates the proliferation of intestinal stem cells in Drosophila | Q34592495 | ||
| The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression. | Q34607947 | ||
| Loss of abhd5 promotes colorectal tumor development and progression by inducing aerobic glycolysis and epithelial-mesenchymal transition | Q34717352 | ||
| Drosophila Myc: A master regulator of cellular performance | Q34873737 | ||
| Biological mechanisms linking obesity and cancer risk: new perspectives | Q35007716 | ||
| Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis | Q35060075 | ||
| Branching morphogenesis of the Drosophila tracheal system. | Q35564860 | ||
| Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila | Q35642076 | ||
| Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality | Q35817986 | ||
| Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors | Q35864565 | ||
| Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype | Q35993087 | ||
| Cancer, type 2 diabetes, and ageing: news from flies and worms | Q36001071 | ||
| Drosophila Cancer Models Identify Functional Differences between Ret Fusions | Q36132331 | ||
| Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila | Q36296267 | ||
| Epidemiology of intracranial meningioma | Q36332389 | ||
| Drosophila models pioneer a new approach to drug discovery for Parkinson's disease | Q36419985 | ||
| Loss of SUFU function in familial multiple meningioma. | Q36439334 | ||
| The Emerging Hallmarks of Cancer Metabolism | Q36468964 | ||
| Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila | Q36548698 | ||
| Extracellular Reactive Oxygen Species Drive Apoptosis-Induced Proliferation via Drosophila Macrophages | Q36614093 | ||
| Signaling pathways that control cell proliferation. | Q36626696 | ||
| Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila | Q36632955 | ||
| The role of lipids in the control of autophagy | Q36655468 | ||
| In vivo regulation of Yorkie phosphorylation and localization. | Q36663448 | ||
| Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition | Q36711814 | ||
| The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy | Q30494710 | ||
| Small molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target | Q30541089 | ||
| Multiple strategies of oxygen supply in Drosophila malignancies identify tracheogenesis as a novel cancer hallmark | Q30627040 | ||
| aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia | Q33279290 | ||
| Drosophila as a model for context-dependent tumorigenesis | Q33666519 | ||
| dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells | Q33707393 | ||
| Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion | Q33715310 | ||
| The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor Survival | Q33737444 | ||
| Kibra is a regulator of the Salvador/Warts/Hippo signaling network | Q33754234 | ||
| Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes | Q33758260 | ||
| Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development | Q33776641 | ||
| Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells | Q33877089 | ||
| Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model | Q33947948 | ||
| Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo | Q34032753 | ||
| Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma | Q34052754 | ||
| From cells to organs: building polarized tissue. | Q34066373 | ||
| A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway | Q34093277 | ||
| The art and design of genetic screens: Drosophila melanogaster | Q34125137 | ||
| Mutations in SUFU predispose to medulloblastoma | Q34133729 | ||
| Interactions between cancer stem cells and their niche govern metastatic colonization | Q34239769 | ||
| A Genetic Screen in Drosophila for Metastatic Behavior | Q34269141 | ||
| Ovarian cancer and body size: individual participant meta-analysis including 25,157 women with ovarian cancer from 47 epidemiological studies | Q34273433 | ||
| Drosophila AP-1: lessons from an invertebrate | Q34279324 | ||
| Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye. | Q34283595 | ||
| Myc Function in Drosophila | Q34291633 | ||
| Macrophage cytokines: involvement in immunity and infectious diseases | Q34299710 | ||
| c-Src drives intestinal regeneration and transformation | Q34324522 | ||
| The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo | Q34356325 | ||
| Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model | Q34374087 | ||
| Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer | Q34398455 | ||
| Evolution of the cancer stem cell model | Q34408981 | ||
| Body mass index and risk of renal cell cancer: a dose-response meta-analysis of published cohort studies | Q34409390 | ||
| Drosophila melanogaster as a model for human intestinal infection and pathology | Q34458779 | ||
| Regulation of cell migration during tracheal development in Drosophila melanogaster | Q34570166 | ||
| The role of adipose tissue immune cells in obesity and low-grade inflammation. | Q38227543 | ||
| Targeting RAS-ERK signalling in cancer: promises and challenges | Q38272894 | ||
| Immune-metabolic interaction in Drosophila | Q38284592 | ||
| dMyc is required for larval growth and endoreplication in Drosophila | Q38341569 | ||
| Myc and Max homologs in Drosophila | Q38351278 | ||
| Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter | Q38497018 | ||
| Supercompetitor status of Drosophila Myc cells requires p53 as a fitness sensor to reprogram metabolism and promote viability | Q38563566 | ||
| Regulation of prostate cancer progression by the tumor microenvironment | Q38717262 | ||
| Lipid desaturation - the next step in targeting lipogenesis in cancer? | Q38735369 | ||
| mTOR Signaling in Growth, Metabolism, and Disease. | Q38747508 | ||
| Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells. | Q38839895 | ||
| MYC, Metabolic Synthetic Lethality, and Cancer | Q38936255 | ||
| Complex interactions between the components of the PI3K/AKT/mTOR pathway, and with components of MAPK, JAK/STAT and Notch-1 pathways, indicate their involvement in meningioma development. | Q38963912 | ||
| A genetic screen in Drosophila for regulators of human prostate cancer progression | Q38966692 | ||
| Modeling Human Cancers in Drosophila | Q39068929 | ||
| Stem-Cell-Based Tumorigenesis in Adult Drosophila | Q39068939 | ||
| JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila | Q39121816 | ||
| Understanding the Intersections between Metabolism and Cancer Biology | Q39130440 | ||
| Emerging Biological Principles of Metastasis | Q39130446 | ||
| Functional exploration of colorectal cancer genomes using Drosophila | Q39145987 | ||
| Non-autonomous cell proliferation in the mammary gland and cancer | Q39185007 | ||
| Prostate organogenesis: tissue induction, hormonal regulation and cell type specification | Q39235902 | ||
| Peritumoral expression of adipokines and fatty acids in breast cancer | Q39347364 | ||
| JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut. | Q39405395 | ||
| Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer. | Q39841937 | ||
| Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression | Q39850326 | ||
| A Serrate-expressing signaling center controls Drosophila hematopoiesis | Q39895131 | ||
| Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis | Q40011318 | ||
| Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. | Q40252270 | ||
| puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila | Q40442820 | ||
| Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells | Q40849132 | ||
| The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling | Q40995001 | ||
| The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth. | Q41072283 | ||
| Microenvironment and tumors-a nurturing relationship | Q41138040 | ||
| A Genetic Screen Reveals an Unexpected Role for Yorkie Signaling in JAK/STAT-Dependent Hematopoietic Malignancies in Drosophila melanogaster | Q41380766 | ||
| Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia | Q41609957 | ||
| EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila | Q41871121 | ||
| Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of Yap | Q42023045 | ||
| Human Cancer Cells Signal Their Competitive Fitness Through MYC Activity | Q42282618 | ||
| Hippo signaling promotes JNK-dependent cell migration | Q42318129 | ||
| Cell Competition: Mechanisms and Physiological Roles. | Q42497354 | ||
| APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression | Q42594428 | ||
| An innate immune response of blood cells to tumors and tissue damage in Drosophila | Q42614126 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | signaling | Q14865172 |
| oncogene | Q207609 | ||
| model organism | Q213907 | ||
| P304 | page(s) | 51 | |
| P577 | publication date | 2019-03-01 | |
| P1433 | published in | Frontiers in Genetics | Q2499875 |
| P1476 | title | Drosophila melanogaster: A Model Organism to Study Cancer | |
| P478 | volume | 10 |
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