DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation

scientific article published on 18 March 2019

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-019-41244-8
P932PMC publication ID6423224
P698PubMed publication ID30886231

P50authorAbdelilah ArredouaniQ58035036
P2093author name stringAbdul Badi Abou-Samra
Mohammed Dehbi
Ramzi Mohammad
Abdoulaye Diane
Mohamed Chikri
Namat Khattab
Ilham Bensmail
Imad Aoude
P2860cites workA method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domainQ24296738
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domainQ24308838
Inflammation, stress, and diabetesQ24523336
Chaperone machines for protein folding, unfolding and disaggregationQ27026110
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)Q28139056
Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activationQ28182501
Regulated transport of the glucose transporter GLUT4Q28216848
Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjectsQ28632230
Glucose transporters in the 21st CenturyQ29302398
Reactive oxygen species have a causal role in multiple forms of insulin resistanceQ29619831
Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistanceQ33646728
Role of pro- and anti-inflammatory phenomena in the physiopathology of type 2 diabetes and obesityQ33711482
Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinaseQ34271504
Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 traffickingQ34449983
Inflammation, metaflammation and immunometabolic disordersQ34550852
DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exerciseQ34873891
c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor.Q34889343
HSP72 protects against obesity-induced insulin resistanceQ36446531
Heat shock proteins induction reduces stress kinases activation, potentially improving insulin signalling in monocytes from obese subjectsQ36502568
Glucolipotoxicity: fuel excess and beta-cell dysfunction.Q36861036
Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitusQ37141727
Inflammation, heat shock proteins, and type 2 diabetesQ37308081
Lilly lecture 1990. Molecular defects in diabetes mellitusQ37681095
Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases.Q37804462
Body composition phenotypes in pathways to obesity and the metabolic syndromeQ37820078
Glutamine Enhances the Hypoglycemic Effect of Insulin in L6 Cells via Phosphatidylinositol-3-Kinase (PI3K)/Protein Kinase B (AKT)/Glucose Transporter 4 (GLUT4) Signaling Pathway.Q54982636
Type 2 diabetes mellitusQ58447602
Hot-tub therapy for type 2 diabetes mellitusQ73023044
Peroxisome proliferator--activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytesQ73661487
Heat shock treatment with mild electrical stimulation safely reduced inflammatory markers in healthy male subjectsQ86961637
The role of mitochondria in insulin resistance and type 2 diabetes mellitusQ37930956
Transforming growth factor-beta1 induces interleukin-6 expression via activating protein-1 consisting of JunD homodimers in primary human lung fibroblasts.Q38325637
DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repressionQ38832980
Cell Signaling and Stress Responses.Q38971267
Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperoneQ39506754
Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.Q40701074
GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulinQ41093949
Deficiency in the Heat Stress Response Could Underlie Susceptibility to Metabolic DiseaseQ42718222
Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat dietQ43177148
Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylationQ43699235
Obesity as a DiseaseQ45305594
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.Q45345766
Markers of Oxidative Stress and Antioxidant Defense in Romanian Patients with Type 2 Diabetes Mellitus and ObesityQ46372448
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)4772
P577publication date2019-03-18
P1433published inScientific ReportsQ2261792
P1476titleDNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
P478volume9

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Q102379380Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperonecites workP2860

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