| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Marco Romano | Q57081759 |
| P2093 | author name string | Giovanna Lombardi | |
| Giorgia Fanelli | |||
| Giulio Giganti | |||
| Caraugh Jane Albany | |||
| P2860 | cites work | DNA methylation controls Foxp3 gene expression | Q46391168 |
| Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3 | Q24672849 | ||
| Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression | Q26744624 | ||
| Regulatory T-Cell Development in the Human Thymus | Q26797326 | ||
| Anti-TNF therapy: past, present and future | Q26997311 | ||
| Regulatory T-cells in pregnancy: historical perspective, state of the art, and burning questions | Q26998637 | ||
| The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer | Q27004062 | ||
| Interaction between natural killer cells and regulatory T cells: perspectives for immunotherapy | Q27008625 | ||
| Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rγnull mice | Q27318356 | ||
| T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. | Q27469830 | ||
| Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Q27860714 | ||
| Neutrophil Dysfunction in Sepsis | Q28079051 | ||
| Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases | Q28131652 | ||
| Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus | Q28268867 | ||
| Cloning and characterization of the thyroid iodide transporter | Q28273142 | ||
| Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease | Q28601365 | ||
| Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells | Q28743652 | ||
| How regulatory T cells work | Q29614262 | ||
| Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation | Q29614840 | ||
| Regulatory T cells and immune tolerance | Q29616864 | ||
| CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells | Q29618394 | ||
| Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function | Q46468450 | ||
| Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells | Q46490320 | ||
| IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer. | Q46885750 | ||
| Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor | Q47740353 | ||
| TNFR2: A Novel Target for Cancer Immunotherapy | Q50069329 | ||
| Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. | Q50536709 | ||
| Engineered T Regulatory Type 1 Cells for Clinical Application. | Q52678018 | ||
| A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials. | Q52725822 | ||
| A pilot study of operational tolerance with a regulatory T-cell-based cell therapy in living donor liver transplantation. | Q52888768 | ||
| Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells. | Q53545523 | ||
| A Phase I Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants. | Q54216691 | ||
| The brave new world of innate lymphoid cells | Q57039150 | ||
| Adoptive Regulatory T Cell Therapy in a Patient with Systemic Lupus Erythematosus | Q57052192 | ||
| Cell surface polysaccharides of induce the generation of Foxp3 regulatory T cells | Q57811360 | ||
| Regulatory T cells induce activation rather than suppression of human basophils | Q58864502 | ||
| Discarded Human Thymus Is a Novel Source of Stable and Long-Lived Therapeutic Regulatory T Cells | Q60451993 | ||
| Approved CAR T cell therapies: ice bucket challenges on glaring safety risks and long-term impacts | Q64005144 | ||
| Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis | Q78404404 | ||
| Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients | Q80154346 | ||
| Inducing and expanding regulatory T cell populations by foreign antigen | Q81392563 | ||
| First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells | Q84135263 | ||
| Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin | Q84307121 | ||
| Neutrophil--CD4+CD25+ T regulatory cell interactions: a possible new mechanism of infectious tolerance | Q84504702 | ||
| 20-year survival post-liver transplant: much more is needed! | Q87015817 | ||
| Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets - results of one year follow-up | Q87620046 | ||
| Regulatory T cells in autoimmune disease | Q89171054 | ||
| CAR T cells for infection, autoimmunity and allotransplantation | Q90475786 | ||
| Expanded Regulatory T Cells Induce Alternatively Activated Monocytes With a Reduced Capacity to Expand T Helper-17 Cells | Q90763598 | ||
| Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells | Q46197984 | ||
| Tolerogenic dendritic cells | Q29618755 | ||
| Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation | Q29620116 | ||
| The role of dendritic cells in autoimmunity | Q30047565 | ||
| Extracellular redox modulation by regulatory T cells | Q30436635 | ||
| Once a Treg, always a Treg? | Q33561651 | ||
| Regulatory T cells differentially modulate the maturation and apoptosis of human CD8+ T-cell subsets. | Q33611828 | ||
| Immunoregulatory functions of mTOR inhibition. | Q33761278 | ||
| TGF-beta/atRA-induced Tregs express a selected set of microRNAs involved in the repression of transcripts related to Th17 differentiation | Q33804010 | ||
| Ex vivo-expanded CD4+CD25+ immunoregulatory T cells prevent graft-versus-host-disease by inhibiting activation/differentiation of pathogenic T cells | Q33992696 | ||
| Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. | Q34038443 | ||
| TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo | Q34044406 | ||
| In vivo SPECT reporter gene imaging of regulatory T cells. | Q34063607 | ||
| Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics | Q34144161 | ||
| Role of LAG-3 in regulatory T cells. | Q34358935 | ||
| Regulatory T cells interfere with glutathione metabolism in dendritic cells and T cells | Q34438825 | ||
| CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. | Q34554035 | ||
| Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice | Q34705919 | ||
| CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages. | Q34718815 | ||
| Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice | Q34831201 | ||
| Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. | Q34969823 | ||
| Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+ regulatory T cells in human peripheral blood. | Q34985717 | ||
| Anti-CD22/CD20 Bispecific antibody with enhanced trogocytosis for treatment of Lupus | Q35170984 | ||
| Targeting Th17 cells in autoimmune diseases | Q35226611 | ||
| Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate | Q35926395 | ||
| Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand | Q35966267 | ||
| Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells | Q35995214 | ||
| Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo | Q36068905 | ||
| CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner | Q36403637 | ||
| Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells | Q36420758 | ||
| Type 1 diabetes immunotherapy using polyclonal regulatory T cells | Q36509805 | ||
| TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T. cell phenotype in the inflammatory environment. | Q36553796 | ||
| T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. | Q36693820 | ||
| Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation | Q36786930 | ||
| Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells | Q36921319 | ||
| Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease | Q36940174 | ||
| Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4(+)CD25(+)FOXP3(+) T regulatory cell subpopulations | Q37060678 | ||
| Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target | Q37111968 | ||
| Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells | Q37180691 | ||
| Pathways of major histocompatibility complex allorecognition. | Q37236992 | ||
| Critical evaluation of regulatory T cells in autoimmunity: are the most potent regulatory specificities being ignored? | Q37272089 | ||
| Cutting edge: Regulatory T cells directly suppress B cells in systemic lupus erythematosus | Q37314612 | ||
| Role of neutrophils in systemic autoimmune diseases | Q37690382 | ||
| Regulatory T cells in stem cell transplantation: strategies and first clinical experiences. | Q37908437 | ||
| Organ transplantation: historical perspective and current practice. | Q37970998 | ||
| Molecular mechanisms of treg-mediated T cell suppression | Q38008361 | ||
| T regulatory cell separation for clinical application. | Q38026324 | ||
| Genetic Factors of Autoimmune Diseases | Q38294652 | ||
| The need for minimization strategies: current problems of immunosuppression. | Q38370826 | ||
| Regulatory T cells: tolerance induction in solid organ transplantation | Q38557841 | ||
| Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants. | Q38662974 | ||
| Treg therapy in transplantation: a general overview. | Q38778543 | ||
| Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation. | Q38918455 | ||
| Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs | Q39016024 | ||
| Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection. | Q39062014 | ||
| The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications | Q39133291 | ||
| Clinical Evidence for the Microbiome in Inflammatory Diseases | Q39265428 | ||
| Type 2 innate lymphoid cell suppression by regulatory T cells attenuates airway hyperreactivity and requires inducible T-cell costimulator-inducible T-cell costimulator ligand interaction | Q39311005 | ||
| Novel treatment strategies in rheumatoid arthritis. | Q39371685 | ||
| Antigen-specific regulatory T cells: are police CARs the answer? | Q39422353 | ||
| Novel role of regulatory T cells in limiting early neutrophil responses in skin | Q39665724 | ||
| AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease | Q39677268 | ||
| Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation. | Q40083199 | ||
| An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment. | Q41139626 | ||
| Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis. | Q41441491 | ||
| The development of T cells from stem cells in mice and humans | Q41609272 | ||
| Abatacept in the treatment of rheumatoid arthritis | Q41905727 | ||
| Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease | Q42000621 | ||
| Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial | Q42232023 | ||
| Molecular mechanisms underlying FOXP3 induction in human T cells | Q42491664 | ||
| Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn's disease | Q42663033 | ||
| HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse. | Q44458617 | ||
| Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis | Q44688981 | ||
| Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients | Q45864185 | ||
| Critical role of IL-2 and TGF-beta in generation, function and stabilization of Foxp3+CD4+ Treg. | Q45993589 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | clinical trial | Q30612 |
| autoimmunity | Q192360 | ||
| transplantation tolerance | Q68665756 | ||
| adoptive immunotherapy | Q72138716 | ||
| P304 | page(s) | 43 | |
| P577 | publication date | 2019-01-31 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | Past, Present, and Future of Regulatory T Cell Therapy in Transplantation and Autoimmunity | |
| P478 | volume | 10 |
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