scholarly article | Q13442814 |
P356 | DOI | 10.1016/S2213-8587(13)70113-X |
P698 | PubMed publication ID | 24622415 |
P50 | author | Michelle Rosenzwajg | Q42238594 |
Olivier Bourron | Q42412294 | ||
David Klatzmann | Q22248690 | ||
P2093 | author name string | Gilbert Bensimon | |
Agnès Hartemann | |||
Claude Bernard | |||
Sophie Jacqueminet | |||
Nathalie Nicolas | |||
Michèle Fonfrede | |||
Christine A Payan | |||
P2860 | cites work | The multiple origins of Type 1 diabetes | Q38062580 |
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Rapamycin causes upregulation of autophagy and impairs islets function both in vitro and in vivo. | Q50510804 | ||
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CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes | Q79843146 | ||
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Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction | Q24650734 | ||
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Regulatory T cells exert checks and balances on self tolerance and autoimmunity | Q28267935 | ||
Clinical toxicity of interleukin-2. | Q33355316 | ||
IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells | Q34096577 | ||
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Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials | Q34318993 | ||
Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases | Q34615216 | ||
Immune intervention in type 1 diabetes. | Q35226251 | ||
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Central role for interleukin-2 in type 1 diabetes | Q35612414 | ||
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity | Q35966086 | ||
Administration of CD4+CD25highCD127- regulatory T cells preserves β-cell function in type 1 diabetes in children | Q36181380 | ||
Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function | Q36182476 | ||
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes | Q36399048 | ||
Interleukin-2 and regulatory T cells in graft-versus-host disease | Q37055805 | ||
Expansion of human regulatory T-cells from patients with type 1 diabetes | Q37105331 | ||
Limitations of IL-2 and rapamycin in immunotherapy of type 1 diabetes | Q37110531 | ||
Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice | Q37141795 | ||
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities | Q37211296 | ||
Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials | Q37307777 | ||
IL-2 and its high-affinity receptor: genetic control of immunoregulation and autoimmunity. | Q37484957 | ||
B cell-directed therapies in type 1 diabetes | Q37870572 | ||
P433 | issue | 4 | |
P921 | main subject | type-1 diabetes | Q124407 |
interleukins | Q194908 | ||
placebo | Q269829 | ||
phase I clinical trial | Q5452194 | ||
phase II clinical trial | Q42824440 | ||
P304 | page(s) | 295-305 | |
P577 | publication date | 2013-10-08 | |
P1433 | published in | The Lancet: Diabetes & Endocrinology | Q27725107 |
P1476 | title | Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial | |
P478 | volume | 1 |
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