scholarly article | Q13442814 |
P50 | author | Nir Hacohen | Q42799920 |
James M Heather | Q56480292 | ||
P2093 | author name string | Thomas Eisenhaure | |
Raktima Raychowdhury | |||
Yuk Yuen Lan | |||
David Lieb | |||
Christopher Stuart Garris | |||
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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts | Q24336806 | ||
Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome | Q24562621 | ||
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Q29617405 | ||
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts | Q29618748 | ||
Transient nuclear envelope rupturing during interphase in human cancer cells. | Q30513945 | ||
Lysosome-mediated processing of chromatin in senescence. | Q30541249 | ||
A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen | Q33532644 | ||
cGAS is essential for cellular senescence | Q33790789 | ||
Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging | Q33847654 | ||
Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status | Q33949558 | ||
Gene regulation and DNA damage in the ageing human brain | Q34326236 | ||
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function | Q34474083 | ||
Differential roles for the interferon-inducible IFI16 and AIM2 innate immune sensors for cytosolic DNA in cellular senescence of human fibroblasts | Q34987881 | ||
Inflammatory markers in population studies of aging | Q34995451 | ||
Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling | Q36020221 | ||
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA | Q36345491 | ||
Interferome v2.0: an updated database of annotated interferon-regulated genes | Q36491580 | ||
Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression | Q36784394 | ||
Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function | Q36907335 | ||
Catastrophic nuclear envelope collapse in cancer cell micronuclei. | Q37111701 | ||
Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses | Q37632327 | ||
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes. | Q37651854 | ||
DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity | Q38908391 | ||
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence. | Q40036388 | ||
Escherichia coli induces DNA double-strand breaks in eukaryotic cells. | Q40244785 | ||
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks | Q40593721 | ||
Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy | Q42060185 | ||
Depletion of the 26S proteasome adaptor Ecm29 increases Toll-like receptor 3 signaling | Q42265452 | ||
Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies. | Q46138874 | ||
Cytoplasmic chromatin triggers inflammation in senescence and cancer | Q46165767 | ||
Type I interferon-mediated autoinflammation due to DNase II deficiency | Q47108722 | ||
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells. | Q52624885 | ||
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death. | Q52878590 | ||
DNA damage response and cellular senescence in tissues of aging mice | Q60284563 | ||
Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study | Q61663307 | ||
Increased cytokine production in mononuclear cells of healthy elderly people | Q72921117 | ||
The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer | Q88286449 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | inflammation | Q101991 |
Dnase2a | Q18250188 | ||
P304 | page(s) | e12901 | |
P577 | publication date | 2019-01-31 | |
P1433 | published in | Aging Cell | Q2221073 |
P1476 | title | Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation | |
P478 | volume | 18 |
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