scholarly article | Q13442814 |
P50 | author | Zoltán Jakus | Q59688198 |
Edina Simon | Q114260337 | ||
P2093 | author name string | Attila Mócsai | |
Petra Aradi | |||
Szilvia Benkő | |||
Dávid S Győri | |||
Csaba Dobó-Nagy | |||
Ahmad Alatshan | |||
Dániel Csete | |||
P2860 | cites work | Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton | Q24293554 |
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk | Q24303475 | ||
RANK is essential for osteoclast and lymph node development | Q24598872 | ||
DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features | Q24672682 | ||
Targeting Syk in Autoimmune Rheumatic Diseases | Q26751042 | ||
Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development | Q28206720 | ||
Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice | Q28207641 | ||
RANKL-RANK signaling in osteoclastogenesis and bone disease | Q28287091 | ||
An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis | Q28294375 | ||
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems | Q28294477 | ||
Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells | Q28505184 | ||
Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr | Q28507457 | ||
Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs | Q28585779 | ||
Syk tyrosine kinase required for mouse viability and B-cell development | Q28586985 | ||
Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk. | Q28588103 | ||
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 | ||
Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption | Q28592760 | ||
A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages | Q28634082 | ||
Osteoclast differentiation and activation | Q29547556 | ||
Zap70 inhibits Syk-mediated osteoclast function | Q30575570 | ||
Bone microenvironment specific roles of ITAM adapter signaling during bone remodeling induced by acute estrogen-deficiency | Q33289959 | ||
Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo | Q33307614 | ||
Repercussion of Megakaryocyte-Specific Gata1 Loss on Megakaryopoiesis and the Hematopoietic Precursor Compartment | Q33432035 | ||
The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils | Q33775026 | ||
Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment | Q33896725 | ||
Lineage-Specific Analysis of Syk Function in Autoantibody-Induced Arthritis. | Q54117883 | ||
Conditional deletion of Bmpr1a in differentiated osteoclasts increases osteoblastic bone formation, increasing volume of remodeling bone in mice. | Q54357688 | ||
Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis. | Q54488975 | ||
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 | ||
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis | Q64077215 | ||
Transgenic mice with hematopoietic and lymphoid specific expression of Cre | Q78842092 | ||
Pathophysiology of bone metastases from solid malignancies | Q88052803 | ||
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts | Q33939357 | ||
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis. | Q34275410 | ||
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts | Q34679499 | ||
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation | Q34920323 | ||
The phosphoinositide 3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption in humans and mice. | Q35040987 | ||
Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells. | Q35071273 | ||
Deletion of Syk in neutrophils prevents immune complex arthritis | Q35269028 | ||
Phospholipase Cγ2 is required for basal but not oestrogen deficiency-induced bone resorption. | Q35697027 | ||
Src and Syk kinases: key regulators of phagocytic cell activation. | Q36083524 | ||
ITAM-based signaling beyond the adaptive immune response. | Q36332906 | ||
Osteoporosis: now and the future | Q36564425 | ||
The SYK tyrosine kinase: a crucial player in diverse biological functions | Q36662082 | ||
Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. | Q36689929 | ||
Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis | Q36944827 | ||
Immunoreceptor-like signaling by beta 2 and beta 3 integrins. | Q36959336 | ||
DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk. | Q36977266 | ||
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism | Q37108966 | ||
Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene | Q37265676 | ||
The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase | Q37647341 | ||
Osteoclasts in RA: diverse origins and functions | Q38111507 | ||
Osteopetrosis: genetics, treatment and new insights into osteoclast function. | Q38123371 | ||
PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2. | Q38744013 | ||
NLRC5 limits the activation of inflammatory pathways | Q39683163 | ||
The signaling adapter protein DAP12 regulates multinucleation during osteoclast development | Q40589041 | ||
The Syk Tyrosine Kinase Is Required for Skin Inflammation in an In Vivo Mouse Model of Epidermolysis Bullosa Acquisita | Q41929292 | ||
Syk is required for integrin signaling in neutrophils | Q43968751 | ||
G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells | Q44280924 | ||
Conditional gene targeting in macrophages and granulocytes using LysMcre mice. | Q44554898 | ||
High dose M-CSF partially rescues the Dap12-/- osteoclast phenotype | Q44660139 | ||
Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial | Q46271720 | ||
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis | Q47761859 | ||
Osteoimmunology: The Conceptual Framework Unifying the Immune and Skeletal Systems. | Q47944184 | ||
Bone-Targeted Therapies in Cancer-Induced Bone Disease | Q48110513 | ||
Recent advances in osteoclast biology. | Q50215136 | ||
Whole-Genome Expression Profiling in Skin Reveals SYK As a Key Regulator of Inflammation in Experimental Epidermolysis Bullosa Acquisita. | Q50333828 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Mice | Q29047609 |
P304 | page(s) | 937 | |
P577 | publication date | 2019-04-30 | |
P1433 | published in | Frontiers in Immunology | Q27723748 |
P1476 | title | Hematopoietic or Osteoclast-Specific Deletion of Syk Leads to Increased Bone Mass in Experimental Mice | |
P478 | volume | 10 |
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