scholarly article | Q13442814 |
P2093 | author name string | Qing Zhang | |
Junhui Chen | |||
Shaobin Wang | |||
Zhendong Yu | |||
P2860 | cites work | Panobinostat in multiple myeloma | Q88761558 |
Belinostat (Beleodaq) for peripheral T-Cell lymphoma | Q95385612 | ||
Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents | Q21198868 | ||
HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling | Q24319032 | ||
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL) | Q24681480 | ||
Recent Advances in Therapeutic Approaches for Adult T-cell Leukemia/Lymphoma | Q26773334 | ||
Romidepsin for the Treatment of Peripheral T-Cell Lymphoma | Q26785732 | ||
Belinostat in patients with refractory or relapsed peripheral T-cell lymphoma: a perspective review | Q26796449 | ||
Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implications | Q26853394 | ||
Development of chidamide for peripheral T-cell lymphoma, the first orphan drug approved in China | Q28070073 | ||
Romidepsin for the treatment of relapsed/refractory cutaneous T-cell lymphoma (mycosis fungoides/Sézary syndrome): Use in a community setting | Q28078806 | ||
The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition | Q28542639 | ||
Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes | Q29398493 | ||
Anticancer activities of histone deacetylase inhibitors | Q29616624 | ||
Clinical Toxicities of Histone Deacetylase Inhibitors | Q31135325 | ||
Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma | Q33375600 | ||
Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma | Q33375694 | ||
FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma | Q33377159 | ||
Vorinostat in solid and hematologic malignancies | Q33385544 | ||
Vorinostat: A novel therapy for the treatment of cutaneous T-cell lymphoma | Q33389625 | ||
Phase II study of the histone deacetylase inhibitor belinostat (PXD101) for the treatment of myelodysplastic syndrome (MDS) | Q33395173 | ||
Panobinostat activity in both bexarotene-exposed and -naïve patients with refractory cutaneous T-cell lymphoma: Results of a phase II trial | Q33403332 | ||
Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies. | Q33405714 | ||
Checkpoint Inhibitors and Other Immune Therapies for Hodgkin and Non-Hodgkin Lymphoma | Q38837680 | ||
Belinostat exerts antitumor cytotoxicity through the ubiquitin-proteasome pathway in lung squamous cell carcinoma | Q38843100 | ||
The predictive value of ERCC1 and p53 for the effect of panobinostat and cisplatin combination treatment in NSCLC. | Q38878715 | ||
Histone deacetylases function as a novel potential therapeutic target for cancer | Q38908331 | ||
Preclinical pharmacologic evaluation of pralatrexate and romidepsin confirms potent synergy of the combination in a murine model of human T-cell lymphoma | Q38910180 | ||
Chidamide, a histone deacetylase inhibitor, functions as a tumor inhibitor by modulating the ratio of Bax/Bcl-2 and P21 in pancreatic cancer | Q38941457 | ||
The novel IKK2 inhibitor LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF-κB. | Q38943920 | ||
A general approach for the development of fluorogenic probes suitable for no-wash imaging of kinases in live cells | Q38944958 | ||
HDACs and HDAC Inhibitors in Cancer Development and Therapy | Q38947405 | ||
Promise of combining a Bcl-2 family inhibitor with bortezomib or SAHA for adult T-cell leukemia/lymphoma. | Q38951433 | ||
Medicinal Chemistry Insights into Novel HDAC Inhibitors: An Updated Patent Review (2012-2016). | Q38996526 | ||
Epigenetic and molecular mechanisms underlying the antileukemic activity of the histone deacetylase inhibitor belinostat in human acute promyelocytic leukemia cells | Q38998021 | ||
Targeting histone deacetylases in T-cell lymphoma | Q38998630 | ||
Non-toxic dose chidamide synergistically enhances platinum-induced DNA damage responses and apoptosis in Non-Small-Cell lung cancer cells. | Q39005535 | ||
Deacetylase inhibitors as a novel modality in the treatment of multiple myeloma | Q39019103 | ||
Current treatment options and investigational drugs for Waldenstrom's Macroglobulinemia | Q39044362 | ||
Vorinostat combined with bexarotene for treatment of cutaneous T-cell lymphoma: in vitro and phase I clinical evidence supporting augmentation of retinoic acid receptor/retinoid X receptor activation by histone deacetylase inhibition | Q39253408 | ||
Panobinostat for the management of multiple myeloma | Q38806260 | ||
Romidepsin and Azacitidine Synergize in their Epigenetic Modulatory Effects to Induce Apoptosis in CTCL. | Q38812165 | ||
Panobinostat for the treatment of acute myelogenous leukemia | Q38835113 | ||
A phase I study to determine the pharmacokinetics and urinary excretion of belinostat and metabolites in patients with advanced solid tumors. | Q39287526 | ||
Antitumor activity of Chidamide in hepatocellular carcinoma cell lines | Q39368032 | ||
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells | Q39395916 | ||
Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity | Q39443782 | ||
Selenium-containing analogs of SAHA induce cytotoxicity in lung cancer cells | Q39653684 | ||
Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T-cell lymphoma models: Defining molecular mechanisms of resistance | Q39744464 | ||
A novel histone deacetylase inhibitor Chidamide induces apoptosis of human colon cancer cells | Q39754297 | ||
In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma | Q39768627 | ||
Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in cutaneous T cell lymphoma | Q39883430 | ||
The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma. | Q40050634 | ||
Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma | Q40070617 | ||
Histone deacetylase inhibitors induce growth arrest and apoptosis of HTLV-1-infected T-cells via blockade of signaling by nuclear factor kappaB. | Q40103966 | ||
Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action | Q40349894 | ||
A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials. | Q40504613 | ||
Long-Term Treatment with Romidepsin in Patients with Peripheral T-Cell Lymphoma | Q41038262 | ||
Action of FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968, on Ha-ras transformed NIH3T3 cells | Q41446518 | ||
The histone deacetylase inhibitor romidepsin synergizes with lenalidomide and enhances tumor cell death in T-cell lymphoma cell lines | Q41573605 | ||
Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells | Q42081115 | ||
Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2 | Q42152675 | ||
Chidamide in relapsed or refractory peripheral T cell lymphoma: a multicenter real-world study in China | Q42316356 | ||
Therapeutic targeting of c-Myc in T-cell acute lymphoblastic leukemia, T-ALL | Q42705204 | ||
Vorinostat(SAHA) Promotes Hyper-Radiosensitivity in Wild Type p53 Human Glioblastoma Cells. | Q42974434 | ||
Arginine butyrate increases the cytotoxicity of DAB(389)IL-2 in leukemia and lymphoma cells by upregulation of IL-2Rbeta gene | Q44223669 | ||
The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells | Q44872972 | ||
Significantly increased CD70 up regulation on TEL-AML positive B cell precursor acute lymphoblastic leukemia cells following CD40 stimulation | Q45284467 | ||
Romidepsin and interferon gamma: A novel combination for refractory cutaneous T-cell lymphoma | Q45811417 | ||
A phase 1 pharmacokinetic and pharmacodynamic study of the histone deacetylase inhibitor belinostat in patients with advanced solid tumors | Q46775253 | ||
Incidence and survival patterns of cutaneous T-cell lymphomas in the United States | Q46778060 | ||
Anti-leukemic effects of HDACi Belinostat and HMTi 3-Deazaneplanocin A on human acute promyelocytic leukemia cells | Q47840446 | ||
FDA Approval: Belinostat for the Treatment of Patients with Relapsed or Refractory Peripheral T-cell Lymphoma | Q49132819 | ||
A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation | Q49156055 | ||
Synergistic antitumor effect of histone deacetylase inhibitor and Doxorubicin in peripheral T-cell lymphoma. | Q50906490 | ||
BCL11B-Mediated Epigenetic Repression Is a Crucial Target for Histone Deacetylase Inhibitors in Cutaneous T-Cell Lymphoma | Q51100298 | ||
Chidamide alleviates TGF-β-induced epithelial-mesenchymal transition in lung cancer cell lines. | Q51462451 | ||
Chidamide and 5-flurouracil show a synergistic antitumor effect on human colon cancer xenografts in nude mice | Q52888741 | ||
Bortezomib and panobinostat combination is effective against PTCL | Q53169774 | ||
Histone Deacetylase in Chronic Lymphocytic Leukemia | Q53192790 | ||
Histone deacetylase inhibitors potentiate photochemotherapy in cutaneous T-cell lymphoma MyLa cells | Q53242291 | ||
Durable clinical remission induced by romidepsin for chemotherapy-refractory peripheral T-cell lymphoma with central nervous system involvement | Q53738710 | ||
Vorinostat | Q56002311 | ||
Molecule of the month. Vorinostat | Q80259707 | ||
Phase I trial of MS-275, a histone deacetylase inhibitor, administered weekly in refractory solid tumors and lymphoid malignancies | Q81310348 | ||
Acetylation controls Notch3 stability and function in T-cell leukemia | Q82696715 | ||
Survivin(g) adult T-cell leukemia/lymphoma | Q82728396 | ||
The efficacy of vorinostat in combination with interferon alpha and extracorporeal photopheresis in late stage mycosis fungoides and Sezary syndrome | Q83760743 | ||
DARTs take aim at BiTEs | Q83992646 | ||
Four proteins governing overangiogenic endothelial cell phenotype in patients with multiple myeloma are plausible therapeutic targets | Q85026964 | ||
Phase I study of vorinostat in combination with standard CHOP in patients with newly diagnosed peripheral T‐cell lymphoma | Q86603764 | ||
The role of T-cell phenotype and T-cell receptor rearrangement in the diagnosis of T-cell malignancies | Q87272757 | ||
Belinostat: first global approval | Q87609508 | ||
Panobinostat in lymphoid and myeloid malignancies | Q33408889 | ||
Phase I study of panobinostat plus everolimus in patients with relapsed or refractory lymphoma | Q33410761 | ||
Lenalidomide in combination with vorinostat and dexamethasone for the treatment of relapsed/refractory peripheral T cell lymphoma (PTCL): report of a phase I/II trial | Q33412763 | ||
A multicentre phase II study of vorinostat in patients with relapsed or refractory indolent B-cell non-Hodgkin lymphoma and mantle cell lymphoma | Q33413857 | ||
A Phase II trial of Belinostat (PXD101) in patients with relapsed or refractory peripheral or cutaneous T-cell lymphoma | Q33418737 | ||
A phase II study of vorinostat and rituximab for treatment of newly diagnosed and relapsed/refractory indolent non-Hodgkin lymphoma. | Q33419840 | ||
Results from a multicenter, open-label, pivotal phase II study of chidamide in relapsed or refractory peripheral T-cell lymphoma | Q33423854 | ||
Combination of romidepsin with cyclophosphamide, doxorubicin, vincristine, and prednisone in previously untreated patients with peripheral T-cell lymphoma: a non-randomised, phase 1b/2 study | Q33428567 | ||
Panobinostat in combination with bortezomib in patients with relapsed or refractory peripheral T-cell lymphoma: an open-label, multicentre phase 2 trial | Q33428575 | ||
A phase II study on the role of gemcitabine plus romidepsin (GEMRO regimen) in the treatment of relapsed/refractory peripheral T-cell lymphoma patients | Q33431457 | ||
A phase I and pharmacokinetic study of the oral histone deacetylase inhibitor, MS-275, in patients with refractory solid tumors and lymphomas | Q33619776 | ||
Vorinostat interferes with the signaling transduction pathway of T-cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T-cell lymphoma. | Q33800456 | ||
Histone deacetylase inhibitors interrupt HSP90•RASGRP1 and HSP90•CRAF interactions to upregulate BIM and circumvent drug resistance in lymphoma cells | Q33808800 | ||
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase | Q34001339 | ||
A phase 2 study of belinostat (PXD101) in patients with relapsed or refractory acute myeloid leukemia or patients over the age of 60 with newly diagnosed acute myeloid leukemia: a California Cancer Consortium Study | Q34084575 | ||
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity | Q34291658 | ||
Chidamide, a novel histone deacetylase inhibitor, synergistically enhances gemcitabine cytotoxicity in pancreatic cancer cells | Q34336020 | ||
Profile of belinostat for the treatment of relapsed or refractory peripheral T-cell lymphoma | Q34434810 | ||
Role of the aggresome pathway in cancer: targeting histone deacetylase 6-dependent protein degradation | Q34770008 | ||
Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy | Q34890457 | ||
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells | Q34994576 | ||
Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin | Q35015901 | ||
Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model | Q35085362 | ||
Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1. | Q35103991 | ||
Histone Deacetylase Inhibitor Belinostat Represses Survivin Expression through Reactivation of Transforming Growth Factor β (TGFβ) Receptor II Leading to Cancer Cell Death | Q35183027 | ||
Romidepsin (Istodax, NSC 630176, FR901228, FK228, depsipeptide): a natural product recently approved for cutaneous T-cell lymphoma | Q35186682 | ||
Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents | Q35214924 | ||
Metabolism as a key to histone deacetylase inhibition | Q35661981 | ||
New developments in the treatment of peripheral T-cell lymphoma - role of Belinostat | Q35703714 | ||
Phase 1 and pharmacologic study of MS-275, a histone deacetylase inhibitor, in adults with refractory and relapsed acute leukemias | Q35750919 | ||
The Therapeutic Potential of AN-7, a Novel Histone Deacetylase Inhibitor, for Treatment of Mycosis Fungoides/Sezary Syndrome Alone or with Doxorubicin | Q35890561 | ||
Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death | Q35922012 | ||
Romidepsin for the Treatment of Peripheral T-Cell Lymphoma. | Q36064937 | ||
Low-dose electron beam radiation and romidepsin therapy for symptomatic cutaneous T-cell lymphoma lesions | Q36066954 | ||
Histone Deacetylase 3 Is Required for Efficient T Cell Development | Q36174093 | ||
Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation | Q36201181 | ||
Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells | Q36203280 | ||
Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma | Q36288249 | ||
A phase I trial of two sequence-specific schedules of decitabine and vorinostat in patients with acute myeloid leukemia. | Q36395421 | ||
Vorinostat Combined with High-Dose Gemcitabine, Busulfan, and Melphalan with Autologous Stem Cell Transplantation in Patients with Refractory Lymphomas. | Q36660672 | ||
MAPK pathway activation leads to Bim loss and histone deacetylase inhibitor resistance: rationale to combine romidepsin with an MEK inhibitor | Q36850845 | ||
Updated survival analysis of a randomized phase III study of subcutaneous versus intravenous bortezomib in patients with relapsed multiple myeloma | Q36936514 | ||
Chidamide, a novel histone deacetylase inhibitor, inhibits the viability of MDS and AML cells by suppressing JAK2/STAT3 signaling | Q37144116 | ||
Double epigenetic modulation of high-dose chemotherapy with azacitidine and vorinostat for patients with refractory or poor-risk relapsed lymphoma. | Q37192391 | ||
Long-term complete remission with belinostat in a patient with chemotherapy refractory peripheral T-cell lymphoma | Q37355651 | ||
Development of vorinostat: current applications and future perspectives for cancer therapy | Q37381104 | ||
Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges | Q37432654 | ||
Clinical studies of histone deacetylase inhibitors. | Q37512917 | ||
Belinostat for Relapsed or Refractory Peripheral T-Cell Lymphoma. | Q37579991 | ||
Responses to romidepsin by line of therapy in patients with relapsed or refractory peripheral T-cell lymphoma | Q37609238 | ||
Histone deacetylase inhibitors inhibit metastasis by restoring a tumor suppressive microRNA-150 in advanced cutaneous T-cell lymphoma. | Q37702571 | ||
The biology of HDAC in cancer: the nuclear and epigenetic components | Q37924191 | ||
Belinostat: clinical applications in solid tumors and lymphoma | Q37951994 | ||
Toxicological and metabolic considerations for histone deacetylase inhibitors | Q38071321 | ||
Histone deacetylase inhibitors: an overview of the clinical studies in solid tumors | Q38159410 | ||
Advances in T-cell therapy for ALL. | Q38278981 | ||
Romidepsin is effective and well tolerated in older patients with peripheral T-cell lymphoma: analysis of two phase II trials | Q38379898 | ||
AFM13: a first-in-class tetravalent bispecific anti-CD30/CD16A antibody for NK cell-mediated immunotherapy | Q38558611 | ||
Lost in translation? Ten years of development of histone deacetylase inhibitors in acute myeloid leukemia and myelodysplastic syndromes | Q38710509 | ||
Panobinostat: A Review in Relapsed or Refractory Multiple Myeloma | Q38716460 | ||
The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies | Q38717046 | ||
A novel histone deacetylase inhibitor Chidamide induces G0/G1 arrest and apoptosis in myelodysplastic syndromes | Q38738628 | ||
Belinostat for the treatment of relapsed or refractory peripheral T-cell lymphoma | Q38752460 | ||
Mechanism, Consequences, and Therapeutic Targeting of Abnormal IL15 Signaling in Cutaneous T-cell Lymphoma | Q38757938 | ||
Histone deacetylase inhibitors as immunomodulators in cancer therapeutics | Q38763747 | ||
An overview of investigational Histone deacetylase inhibitors (HDACis) for the treatment of non-Hodgkin's lymphoma | Q38765451 | ||
Induction of apoptosis by HBI-8000 in adult T-cell leukemia/lymphoma is associated with activation of Bim and NLRP3. | Q38770098 | ||
Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells. | Q38791801 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial | Q6936496 |
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | T-cell lymphoma | Q7667896 |
targeted therapy | Q492646 | ||
histone deacetylase inhibitors | Q3569101 | ||
peripheral T-cell lymphoma | Q7168693 | ||
Cutaneous T‐cell lymphoma | Q58748290 | ||
P304 | page(s) | 424-442 | |
P577 | publication date | 2019-01-01 | |
2019-01-29 | |||
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | International Journal of Medical Sciences | Q10927439 |
P1476 | title | Histone Deacetylases (HDACs) Guided Novel Therapies for T-cell lymphomas | |
P478 | volume | 16 |