UNC5D, suppressed by promoter hypermethylation, inhibits cell metastasis by activating death-associated protein kinase 1 in prostate cancer

scientific article published on 20 February 2019

UNC5D, suppressed by promoter hypermethylation, inhibits cell metastasis by activating death-associated protein kinase 1 in prostate cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/CAS.13935
P932PMC publication ID6447834
P698PubMed publication ID30632669

P50authorYunli ZhouQ90042567
P2093author name stringLi Ren
Li Jia
Dong Dong
Wei Ji
Na Ma
Aimin Zhang
Lufang Zhang
Pengyu Zhang
Changsen Bai
P2860cites workAkt is negatively regulated by the MULAN E3 ligaseQ24307478
The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinaseQ24318638
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The dependence receptor UNC5H2 mediates apoptosis through DAP-kinaseQ24555713
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitmentQ24683182
Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: its relationship to clinical outcomeQ24800480
Death and anti-death: tumour resistance to apoptosisQ28217065
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FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neuronsQ28571301
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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancerQ29614277
The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway.Q30480366
Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryosQ33459129
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Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regressionQ34351731
Assessment of hepatocyte growth factor in ovarian cancer mortalityQ35156876
Mechanisms of resistance to TRAIL-induced apoptosis in cancerQ35954258
Quantitative analyses of DAPK1 methylation in AML and MDSQ36296317
Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancerQ36468744
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Epigenetic alterations in human prostate cancers.Q37328845
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DAPK and cytoskeleton-associated functionsQ38156051
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Unc5D regulates p53-dependent apoptosis in neuroblastoma cellsQ39009277
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Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivoQ41288594
DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activityQ41848995
Death-associated protein kinase is activated by dephosphorylation in response to cerebral ischemiaQ44127953
Impact of the Site of Metastases on Survival in Patients with Metastatic Prostate CancerQ45054328
Cloning of three mouse Unc5 genes and their expression patterns at mid-gestationQ48480024
Down-regulation of UNC5D in bladder cancer: UNC5D as a possible mediator of cisplatin induced apoptosis in bladder cancer cells.Q54223189
DAP kinase links the control of apoptosis to metastasisQ59083516
Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis--A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens fromQ73119476
Resistance to CD95 (APO-1/Fas)-mediated apoptosis in human renal cell carcinomas: an important factor for evasion from negative growth controlQ73313982
Ovarian cancer statistics, 2018Q88890110
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectexpressionQ778379
hypermethylationQ106875739
P304page(s)1244-1255
P577publication date2019-02-20
P1433published inCancer ScienceQ326125
P1476titleUNC5D, suppressed by promoter hypermethylation, inhibits cell metastasis by activating death-associated protein kinase 1 in prostate cancer
P478volume110

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Q92737473Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancercites workP2860

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