| scholarly article | Q13442814 |
| P50 | author | Simon S Skene | Q55979476 |
| P2093 | author name string | Nigel H Greig | |
| Thomas Foltynie | |||
| Dimitrios Kapogiannis | |||
| Maja Mustapic | |||
| Yazhou Li | |||
| Seema Gulyani | |||
| Kashfia Chowdhury | |||
| David Tweedie | |||
| Sahil Chawla | |||
| Dilan Athauda | |||
| Hanuma Kumar Karnati | |||
| P2860 | cites work | Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? | Q21129257 |
| Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line | Q24609542 | ||
| Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson's Disease | Q26750370 | ||
| p38 MAPK and PI3K/AKT Signalling Cascades inParkinson's Disease | Q26799375 | ||
| Parkinson's disease, insulin resistance and novel agents of neuroprotection | Q26853311 | ||
| Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson's disease. | Q27322563 | ||
| Positive and negative regulation of insulin signaling through IRS-1 phosphorylation | Q28236905 | ||
| RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation | Q28568796 | ||
| Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases | Q29614910 | ||
| Insulin resistance in brain alters dopamine turnover and causes behavioral disorders. | Q30631520 | ||
| Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease | Q33628048 | ||
| Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes. | Q33711915 | ||
| High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice | Q33850466 | ||
| Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells | Q34028497 | ||
| Neurodegeneration in an animal model of Parkinson's disease is exacerbated by a high-fat diet | Q34212422 | ||
| Standardization of sample collection, isolation and analysis methods in extracellular vesicle research | Q34369038 | ||
| Diabetes and risk of Parkinson's disease | Q34718429 | ||
| Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis | Q34760248 | ||
| Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease | Q35039301 | ||
| Diabetes and the risk of developing Parkinson's disease in Denmark. | Q35043736 | ||
| Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study | Q35085348 | ||
| Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling. | Q35196491 | ||
| Insulin resistance impairs nigrostriatal dopamine function | Q35202338 | ||
| An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers | Q35858008 | ||
| Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer disease-associated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes | Q48422656 | ||
| High complement levels in astrocyte-derived exosomes of Alzheimer's disease | Q50182771 | ||
| Exendin-4 promotes proliferation and differentiation of MC3T3-E1 osteoblasts by MAPKs activation | Q50276729 | ||
| Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats. | Q50963300 | ||
| The Glucagon-Like Peptide-1 Analogue Liraglutide Inhibits Oxidative Stress and Inflammatory Response in the Liver of Rats with Diet-Induced Non-alcoholic Fatty Liver Disease. | Q51303447 | ||
| Exendin-4 reduces tau hyperphosphorylation in type 2 diabetic rats via increasing brain insulin level. | Q52145436 | ||
| Exendin-4 Promotes Beta Cell Proliferation via PI3k/Akt Signalling Pathway. | Q54276620 | ||
| Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease | Q56567928 | ||
| Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance | Q56743508 | ||
| Cooperative action of JNK and AKT/mTOR in 1-methyl-4-phenylpyridinium-induced autophagy of neuronal PC12 cells | Q58467727 | ||
| Rapamycin protects the mitochondria against oxidative stress and apoptosis in a rat model of Parkinson's disease | Q86175425 | ||
| Metabolic inflammation exacerbates dopaminergic neuronal degeneration in response to acute MPTP challenge in type 2 diabetes mice | Q95465407 | ||
| Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline | Q35858095 | ||
| Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling | Q35858131 | ||
| Effects of Exendin-4 on bone marrow mesenchymal stem cell proliferation, migration and apoptosis in vitro | Q35926017 | ||
| Eating high fat chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adolescents | Q35965902 | ||
| Brain GLP-1 and insulin sensitivity | Q35991683 | ||
| A dual role for the cAMP-dependent protein kinase in tyrosine hydroxylase gene expression | Q36246194 | ||
| Prospective cohort study of type 2 diabetes and the risk of Parkinson's disease | Q36906241 | ||
| Glucagon-like peptide 1 reduces endothelial dysfunction, inflammation, and oxidative stress induced by both hyperglycemia and hypoglycemia in type 1 diabetes | Q37022682 | ||
| Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease | Q37151436 | ||
| Glucose-Dependent Insulinotropic Polypeptide Ameliorates Mild Traumatic Brain Injury-Induced Cognitive and Sensorimotor Deficits and Neuroinflammation in Rats | Q37424923 | ||
| Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification? | Q38192319 | ||
| Effects of diet and insulin on dopamine transporter activity and expression in rat caudate-putamen, nucleus accumbens, and midbrain. | Q38289781 | ||
| Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward | Q38295730 | ||
| Methods for extracellular vesicles isolation in a hospital setting. | Q38391453 | ||
| Intranasal Administration of GDNF Protects Against Neural Apoptosis in a Rat Model of Parkinson's Disease Through PI3K/Akt/GSK3β Pathway | Q38714411 | ||
| Neuroendocrine abnormalities in Parkinson's disease | Q38801525 | ||
| Insulin resistance and Parkinson's disease: A new target for disease modification? | Q38807899 | ||
| Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling | Q38894507 | ||
| Neuroprotective and anti-apoptotic effects of liraglutide on SH-SY5Y cells exposed to methylglyoxal stress | Q39083326 | ||
| Methodological Guidelines to Study Extracellular Vesicles | Q39299869 | ||
| AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Q39776724 | ||
| Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells | Q40592531 | ||
| Exenatide Regulates Substrate Preferences Through the p38γ MAPK Pathway After Ischaemia/Reperfusion Injury in a Rat Heart | Q40602340 | ||
| Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling | Q40615721 | ||
| Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease | Q40887263 | ||
| Exendin-4 suppresses SRC activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner | Q41531028 | ||
| Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration | Q42114376 | ||
| Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment | Q42148662 | ||
| Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner | Q42409261 | ||
| Irs1 serine 307 promotes insulin sensitivity in mice | Q42563623 | ||
| Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease | Q42705476 | ||
| The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease. | Q42715682 | ||
| TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. | Q43166689 | ||
| 5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside | Q43764668 | ||
| Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease | Q44909742 | ||
| Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity | Q45275310 | ||
| In a randomized trial in prostate cancer patients, dietary protein restriction modifies markers of leptin and insulin signaling in plasma extracellular vesicles | Q46624859 | ||
| Exosomes are released by cultured cortical neurones. | Q46918951 | ||
| Elevated nuclear phosphatase and tensin homolog (PTEN) and altered insulin signaling in substantia nigral region of patients with Parkinson's disease | Q47232875 | ||
| ALCAR promote adult hippocampal neurogenesis by regulating cell-survival and cell death-related signals in rat model of Parkinson's disease like-phenotypes | Q47867574 | ||
| Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial | Q48164658 | ||
| Insulin resistance and exendin-4 treatment for multiple system atrophy. | Q48249047 | ||
| Exendin-4 improved rat cortical neuron survival under oxygen/glucose deprivation through PKA pathway | Q48366558 | ||
| P433 | issue | 4 | |
| P921 | main subject | Parkinson's disease | Q11085 |
| P304 | page(s) | 420-429 | |
| P577 | publication date | 2019-04-01 | |
| P1433 | published in | JAMA Neurology | Q276813 |
| P1476 | title | Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease: A Secondary Analysis of the Exenatide-PD Trial | |
| P478 | volume | 76 |
| Q90061894 | Altered Levels of Toll-Like Receptors in Circulating Extracellular Vesicles in Multiple Sclerosis |
| Q93164263 | An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders |
| Q64102563 | Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer's Precision Medicine and Pharmacology |
| Q95270052 | Downregulation of eEF1A/EFT3-4 Enhances Dopaminergic Neurodegeneration After 6-OHDA Exposure in C. elegans Model |
| Q64067288 | Error in Byline |
| Q90144171 | Exosome and Biomimetic Nanoparticle Therapies for Cardiac Regenerative Medicine |
| Q92925359 | Extracellular Vesicle Biomarkers Track Cognitive Changes Following Intranasal Insulin in Alzheimer's Disease |
| Q91421330 | GBA1 mutations: Prospects for exosomal biomarkers in α-synuclein pathologies |
| Q92513493 | Incretin Mimetics as Rational Candidates for the Treatment of Traumatic Brain Injury |
| Q64906306 | Insulin and Autophagy in Neurodegeneration. |
| Q90565715 | Insulin-signaling abnormalities in drug-naïve first-episode schizophrenia: Transduction protein analyses in extracellular vesicles of putative neuronal origin |
| Q93159914 | Multi-omics signature of brain amyloid deposition in asymptomatic individuals at-risk for Alzheimer's disease: The INSIGHT-preAD study |
| Q93054879 | Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain Injury |
| Q90181986 | Potential Roles of Exosomes in Parkinson's Disease: From Pathogenesis, Diagnosis, and Treatment to Prognosis |
| Q90855717 | Promise of extracellular vesicles for diagnosis and treatment of epilepsy |
| Q89907040 | Targetting Exosomes as a New Biomarker and Therapeutic Approach for Alzheimer's Disease |
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