scholarly article | Q13442814 |
P50 | author | Steven E. Arnold | Q64157128 |
P2093 | author name string | Yong Chen | |
Irwin Lucki | |||
Sangwon F Kim | |||
Sookhee Bang | |||
Bethany R Brookshire | |||
Caroline A Browne | |||
Gregory C Carlson | |||
Bo-Ran Choi | |||
Hala Kazi | |||
Mary F McMullen | |||
P2860 | cites work | Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP | Q22251081 |
NIH Image to ImageJ: 25 years of image analysis | Q23319322 | ||
From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase | Q24685521 | ||
The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses | Q28142887 | ||
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase | Q28215845 | ||
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus | Q28254114 | ||
LTP inhibits LTD in the hippocampus via regulation of GSK3beta | Q28290606 | ||
ProSAP/Shank postsynaptic density proteins interact with insulin receptor tyrosine kinase substrate IRSp53 | Q28579738 | ||
Endogenous insulin signaling protects cultured neurons from oxygen-glucose deprivation-induced cell death | Q28580812 | ||
Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways | Q28581081 | ||
AMPK: a nutrient and energy sensor that maintains energy homeostasis | Q29615410 | ||
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism | Q29617261 | ||
Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression | Q30453017 | ||
High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling | Q30496730 | ||
The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes | Q31131756 | ||
High-fat diet impairs hippocampal neurogenesis in male rats | Q33264117 | ||
The association of posttraumatic stress disorder and metabolic syndrome: a study of increased health risk in veterans | Q33398794 | ||
Cognitive impairment following high fat diet consumption is associated with brain inflammation. | Q33665160 | ||
Chronic stress alters synaptic terminal structure in hippocampus | Q33741453 | ||
Cognition and synaptic plasticity in diabetes mellitus | Q33925012 | ||
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state | Q33968008 | ||
Insulin metabolism and the risk of Alzheimer disease: the Rotterdam Study | Q34458197 | ||
Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB. | Q34533714 | ||
Insulin resistance and Alzheimer's disease: molecular links & clinical implications. | Q34657393 | ||
Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? | Q34669518 | ||
Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo | Q34674963 | ||
Bidirectional association between depression and type 2 diabetes mellitus in women | Q34729968 | ||
Metabolic syndrome: definitions and controversies. | Q35047747 | ||
Depressive phenotypes evoked by experimental diabetes are reversed by insulin | Q35613538 | ||
AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase | Q35673731 | ||
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline | Q35858095 | ||
The value of spontaneous alternation behavior (SAB) as a test of retention in pharmacological investigations of memory | Q35909381 | ||
An overview of the tasks used to test working memory in rodents | Q35957696 | ||
Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain | Q36107303 | ||
p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake | Q36125261 | ||
Insulin resistance and Alzheimer's disease | Q36143429 | ||
Studies of the effects of high fat diets on cognitive function in a rat model | Q36283934 | ||
Risk of dementia in diabetes mellitus: a systematic review | Q36345254 | ||
Olfactory ability and object memory in three mouse models of varying body weight, metabolic hormones, and adiposity | Q36442518 | ||
Control of energy homeostasis: role of enzymes and intermediates of fatty acid metabolism in the central nervous system | Q36480505 | ||
AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues | Q36482341 | ||
Hypothalamic phosphatidylinositol 3-kinase pathway of leptin signaling is impaired during the development of diet-induced obesity in FVB/N mice | Q36509764 | ||
Therapy Insight: type 2 diabetes mellitus and the risk of late-onset Alzheimer's disease | Q36577266 | ||
Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity | Q37013755 | ||
Effects of diabetes on hippocampal neurogenesis: links to cognition and depression | Q37210037 | ||
Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. | Q37222582 | ||
Experimental diabetes in rats causes hippocampal dendritic and synaptic reorganization and increased glucocorticoid reactivity to stress | Q37272272 | ||
Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease | Q37332266 | ||
Bipolar disorder and metabolic syndrome: an international perspective | Q37764504 | ||
The metabolic syndrome: time to get off the merry-go-round? | Q37815542 | ||
Insulin, synaptic function, and opportunities for neuroprotection | Q37825696 | ||
Metabolic and cardiovascular adverse effects associated with antipsychotic drugs | Q37947095 | ||
Dendritic mRNA targeting and translation | Q37986661 | ||
Hypothalamic dysfunction in obesity | Q38041229 | ||
Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice. | Q38324750 | ||
Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours | Q38344515 | ||
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase | Q39599480 | ||
Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer's-like changes | Q39600965 | ||
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner | Q39707409 | ||
Meta-analysis of Alzheimer's disease risk with obesity, diabetes, and related disorders | Q39988561 | ||
Akt/PKB controls the activity-dependent bulk endocytosis of synaptic vesicles | Q41520547 | ||
Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. | Q41841220 | ||
Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain | Q42053859 | ||
Striatum specific protein, Rhes regulates AKT pathway | Q42119034 | ||
High-fat diets induce changes in hippocampal glutamate metabolism and neurotransmission | Q42497945 | ||
Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents | Q42524355 | ||
Actions of incretin metabolites on locomotor activity, cognitive function and in vivo hippocampal synaptic plasticity in high fat fed mice. | Q42642299 | ||
Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance | Q42870607 | ||
Regulation of presynaptic neurotransmission by macroautophagy | Q43242957 | ||
Learning and memory impairment in rats fed a high saturated fat diet | Q44087016 | ||
Roles of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in hippocampal neurons | Q46451108 | ||
Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus. | Q46608450 | ||
Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner | Q46644037 | ||
Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III. | Q46683011 | ||
Non-insulin-dependent diabetes mellitus is associated with a greater prevalence of depression in the elderly. The Osservatorio Geriatrico of Campania Region Group | Q47629019 | ||
Rates and risks for co-morbid depression in patients with Type 2 diabetes mellitus: results from a community-based study | Q47813282 | ||
Improved insulin sensitivity in 80 nondiabetic patients with MDD after clinical remission in a double-blind, randomized trial of amitriptyline and paroxetine. | Q48325818 | ||
The effect of simvastatin treatment on behavioral parameters, cognitive performance, and hippocampal morphology in rats fed a standard or a high-fat diet | Q48439680 | ||
Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice. | Q48467415 | ||
Juvenile, but not adult exposure to high-fat diet impairs relational memory and hippocampal neurogenesis in mice. | Q48508670 | ||
Impairment of fear-conditioning responses and changes of brain neurotrophic factors in diet-induced obese mice | Q48577609 | ||
High-fat diets impair spatial learning in the radial-arm maze in mice. | Q51029956 | ||
Insulin resistance in patients with depression and its changes during the clinical course of depression: minimal model analysis. | Q51552638 | ||
High-fat diet induced neuropathy of pre-diabetes and obesity: effects of "healthy" diet and aldose reductase inhibition. | Q51746503 | ||
Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis | Q82747467 | ||
Localization and Characterization of Insulin-Like Growth Factor-I Receptors in Rat Brain and Pituitary Gland Using in vitro Autoradiography and Computerized Densitometry* A Distinct Distribution from Insulin Receptors | Q83330616 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P921 | main subject | insulin resistance | Q1053470 |
preproinsulin | Q7240673 | ||
P304 | page(s) | 79-87 | |
P577 | publication date | 2014-03-29 | |
P1433 | published in | Neurobiology of Disease | Q15716606 |
P1476 | title | High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice | |
P478 | volume | 67 |
Q92862273 | A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer's Disease |
Q41992910 | A High-fat Diet Induces a Loss of Midbrain Dopaminergic Neuronal Function That Underlies Motor Abnormalities. |
Q43066217 | Adiponectin receptor-mediated signaling ameliorates cerebral cell damage and regulates the neurogenesis of neural stem cells at high glucose concentrations: an in vivo and in vitro study |
Q98945320 | Beneficial Effect of Genistein on Diabetes-Induced Brain Damage in the ob/ob Mouse Model |
Q92649188 | Brain Insulin Resistance and Hippocampal Plasticity: Mechanisms and Biomarkers of Cognitive Decline |
Q47106495 | Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a. |
Q47835103 | Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums |
Q47256044 | Brain-derived neurotropic factor (BDNF) heterozygous mice are more susceptible to synaptic protein loss in cerebral cortex during high fat diet. |
Q48333942 | Cardiotrophin-1 (CT-1) improves high fat diet-induced cognitive deficits in mice |
Q39255704 | Cholesterol as a modifying agent of the neurovascular unit structure and function under physiological and pathological conditions |
Q38618122 | Cognitive impairment and gene expression alterations in a rodent model of binge eating disorder |
Q54967973 | Cognitive impairment in metabolically-obese, normal-weight rats: identification of early biomarkers in peripheral blood mononuclear cells. |
Q64067855 | Combined Effect of Fatty Diet and Cognitive Decline on Brain Metabolism, Food Intake, Body Weight, and Counteraction by Intranasal Insulin Therapy in 3×Tg Mice |
Q41995767 | Diabesity and Brain Energy Metabolism: The Case of Alzheimer's Disease |
Q90319593 | Diabetes and Alzheimer's Disease: A Link not as Simple as it Seems |
Q27321064 | Dietary Reversal Ameliorates Short- and Long-Term Memory Deficits Induced by High-fat Diet Early in Life |
Q38525428 | Effects of high-fat diet exposure on learning & memory |
Q64264817 | Effects of rosuvastatin on metabolic profile: Versatility of dose-dependent effect |
Q60923806 | Etiology of Metabolic Syndrome and Dietary Intervention |
Q48547338 | Evaluation of Neuropathological Effects of a High-Fat Diet in a Presymptomatic Alzheimer's Disease Stage in APP/PS1 Mice |
Q90167863 | Exercise and metformin counteract altered mitochondrial function in the insulin-resistant brain |
Q47919673 | FGF21 Attenuates High-Fat Diet-Induced Cognitive Impairment via Metabolic Regulation and Anti-inflammation of Obese Mice |
Q37580106 | Genetic variability to diet-induced hippocampal dysfunction in BXD recombinant inbred (RI) mouse strains |
Q64911679 | Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism. |
Q41654655 | High fat diet augments amphetamine sensitization in mice: Role of feeding pattern, obesity, and dopamine terminal changes |
Q21131756 | High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity |
Q37005127 | High-fat diet-induced metabolic disorders impairs 5-HT function and anxiety-like behavior in mice |
Q35827711 | High-fat diet-induced obesity exacerbates kainic acid-induced hippocampal cell death |
Q38606226 | Hippocampal insulin resistance and cognitive dysfunction |
Q35905362 | Insulin Resistance Prevents AMPK-induced Tau Dephosphorylation through Akt-mediated Increase in AMPKSer-485 Phosphorylation |
Q63805071 | Insulin Resistance and Oxidative Stress in the Brain: What's New? |
Q59808617 | Insulin Resistance in Alzheimer's Disease |
Q27008997 | Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome |
Q56334573 | Insulin transport into the brain |
Q58781043 | Links Between Obesity-Induced Brain Insulin Resistance, Brain Mitochondrial Dysfunction, and Dementia |
Q39849726 | Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase, Dexras1. |
Q91732862 | Maternal high-fat diet results in cognitive impairment and hippocampal gene expression changes in rat offspring |
Q90883982 | Maternal insulin resistance multigenerationally impairs synaptic plasticity and memory via gametic mechanisms |
Q38967795 | Maternal obesity and neurodevelopmental and psychiatric disorders in offspring. |
Q89832023 | Maternal stressors and the developmental origins of neuropsychiatric risk |
Q64235454 | Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats |
Q90286845 | Metabolic Disturbances of a High-Fat Diet Are Dependent on APOE Genotype and Sex |
Q92814997 | Metabolic Stress Alters Antioxidant Systems, Suppresses the Adiponectin Receptor 1 and Induces Alzheimer's Like Pathology in Mice Brain |
Q33625557 | Metaflammasome components in the human brain: a role in dementia with Alzheimer's pathology? |
Q55338665 | MicroRNA Expression Profiling in the Prefrontal Cortex: Putative Mechanisms for the Cognitive Effects of Adolescent High Fat Feeding. |
Q37613304 | Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's Disease |
Q34914164 | Molecular targets of the multifunctional iron-chelating drug, M30, in the brains of mouse models of type 2 diabetes mellitus |
Q42167847 | Naringin Improves Neuronal Insulin Signaling, Brain Mitochondrial Function, and Cognitive Function in High-Fat Diet-Induced Obese Mice |
Q60916495 | Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet |
Q48909259 | Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential Link to Cognitive Impairment in Schizophrenia |
Q26765753 | Obesity Reduces Cognitive and Motor Functions across the Lifespan |
Q58085042 | Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer's disease and normalized by treatment with anti-diabetic agents |
Q35618949 | Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans. |
Q47222898 | Pyruvate induces torpor in obese mice |
Q92703384 | Serine Phosphorylation of IRS1 Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD |
Q36651084 | Stop signs in hippocampal insulin signaling: the role of insulin resistance in structural, functional and behavioral deficits |
Q54967979 | Stress exposure alters brain mRNA expression of the genes involved in insulin signalling, an effect modified by a high fat/high fructose diet and cinnamon supplement. |
Q33604879 | Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants |
Q58610974 | TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity |
Q92510169 | Targeting the Synapse in Alzheimer's Disease |
Q60959857 | The Effect of Intrahippocampal Insulin Infusion on Spatial Cognitive Function and Markers of Neuroinflammation in Diet-induced Obesity |
Q89879822 | The Effects of Early Life Stress, Postnatal Diet Modulation, and Long-Term Western-Style Diet on Later-Life Metabolic and Cognitive Outcomes |
Q26766454 | The Role of Steroid Hormones in the Modulation of Neuroinflammation by Dietary Interventions |
Q60934892 | The Synergistic Effects of APOE Genotype and Obesity on Alzheimer's Disease Risk |
Q38823805 | Therapeutic Potential of Antidiabetic Medications in the Treatment of Cognitive Dysfunction and Dementia |
Q36395944 | Thidoredxin-2 overexpression fails to rescue chronic high calorie diet induced hippocampal dysfunction. |
Q48470200 | Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway |
Q90529872 | Time-course study of high fat diet induced alterations in spatial memory, hippocampal JNK, P38, ERK and Akt activity |
Q48935013 | Traumatic brain injury and obesity induce persistent central insulin resistance |
Q35866744 | Unaltered Prion Pathogenesis in a Mouse Model of High-Fat Diet-Induced Insulin Resistance |
Q92987203 | Use of high-fat diets to study rodent obesity as a model of human obesity |
Q64785443 | Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease: A Secondary Analysis of the Exenatide-PD Trial |
Q37632960 | Western Diet Chow Consumption in Rats Induces Striatal Neuronal Activation While Reducing Dopamine Levels without Affecting Spatial Memory in the Radial Arm Maze. |
Q36072025 | ZiBu PiYin recipe prevents diabetes-associated cognitive decline in rats: possible involvement of ameliorating mitochondrial dysfunction, insulin resistance pathway and histopathological changes |
Search more.