Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells.

scientific article published on 27 May 2019

Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1186/S11658-019-0159-8
P932PMC publication ID6537441
P698PubMed publication ID31160892

P2093author name stringMallika Valapala
Abdulla H Alamri
Hsuan-Yeh Pan
P2860cites workCellular and molecular mechanisms of age-related macular degeneration: from impaired autophagy to neovascularization.Q38100515
An overview of autophagy: morphology, mechanism, and regulationQ38110938
The MITF family of transcription factors: Role in endolysosomal biogenesis, Wnt signaling, and oncogenesis.Q38499810
Transcription factor EB: from master coordinator of lysosomal pathways to candidate therapeutic target in degenerative storage diseasesQ38864723
Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment.Q39171305
Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activityQ39893895
TFEB and TFE3: The art of multi-tasking under stress conditionsQ45256565
The Lysosome as a Regulatory Hub.Q46028598
Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interactionQ46745668
Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activityQ60044948
Acidification of phagosomes and degradation of rod outer segments in rat retinal pigment epitheliumQ72254151
Lysosomal enhancement: a CLEAR answer to cellular degradative needsQ84965479
Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expressionQ24316369
A gene network regulating lysosomal biogenesis and functionQ24339409
A lysosome-centered view of nutrient homeostasisQ28073435
Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagyQ28263676
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEBQ30508509
The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasisQ30524831
Phagocytosis of retinal rod and cone photoreceptorsQ33731918
Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signalingQ33831329
The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epitheliumQ34020740
Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in cultureQ34090518
The role of the retinal pigment epithelium: topographical variation and ageing changesQ34307040
Lysosomotropic agents as HCV entry inhibitors.Q34957340
Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvationQ35212557
Ammonium chloride, an inhibitor of phagosome-lysosome fusion in macrophages, concurrently induces phagosome-endosome fusion, and opens a novel pathway: studies of a pathogenic mycobacterium and a nonpathogenic yeastQ36230420
Lysosomal adaptation: How cells respond to lysosomotropic compoundsQ36310581
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.Q36709792
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicityQ36835587
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loopQ36977543
TFEB: Pathogenic role and therapeutic target in Parkinson diseaseQ37107143
Autophagy: a lysosomal degradation pathway with a central role in health and diseaseQ37245031
How nascent phagosomes mature to become phagolysosomesQ38007730
P4510describes a project that usesImageJQ1659584
P304page(s)33
P577publication date2019-05-27
P1433published inCellular & Molecular Biology LettersQ15749454
P1476titleNutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells.
P478volume24

Reverse relations

Q98463750Presenilin 1 phosphorylation regulates amyloid-β degradation by microgliacites workP2860

Search more.