Cytotoxic Effect of Paclitaxel and Lapatinib Co-Delivered in Polylactide-co-Poly(ethylene glycol) Micelles on HER-2-Negative Breast Cancer Cells.

scientific article published on 6 April 2019

Cytotoxic Effect of Paclitaxel and Lapatinib Co-Delivered in Polylactide-co-Poly(ethylene glycol) Micelles on HER-2-Negative Breast Cancer Cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/PHARMACEUTICS11040169
P932PMC publication ID6523169
P698PubMed publication ID30959904

P50authorJanusz Edward KasperczykQ17544572
Katarzyna JelonekQ61946998
Adam WilczokQ70270614
Alicja ZajdelQ78064653
Monika Musiał-KulikQ87222608
Aleksander ForyśQ90702215
P2093author name stringSuming Li
P2860cites workHigh Bak Expression Is Associated with a Favorable Prognosis in Breast Cancer and Sensitizes Breast Cancer Cells to PaclitaxelQ28548522
A novel combined micellar system of lapatinib and Paclitaxel with enhanced antineoplastic effect against human epidermal growth factor receptor-2 positive breast tumor in vitroQ30871548
DDSolver: an add-in program for modeling and comparison of drug dissolution profilesQ33550419
Cellular mechanisms of multidrug resistance of tumor cells.Q33854298
Modeling and comparison of dissolution profilesQ34215811
Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters.Q36143777
Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinasesQ37274044
P-glycoprotein-activity measurements in multidrug resistant cell lines: single-cell versus single-well population fluorescence methodsQ37358540
Microtubules and resistance to tubulin-binding agentsQ37690565
Taxane resistance in breast cancer: mechanisms, predictive biomarkers and circumvention strategiesQ37998748
Emerging nanotherapeutic strategies in breast cancerQ38161649
Polymeric micelles: nanocarriers for cancer-targeted drug deliveryQ38202058
Tyrosine kinase inhibitors as reversal agents for ABC transporter mediated drug resistance.Q38246305
The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decadeQ38305824
Polymeric Micelles: Recent Advancements in the Delivery of Anticancer Drugs.Q38588547
Recent advances in polymeric micelles for anti-cancer drug deliveryQ38690785
In vitro and in vivo evaluation of paclitaxel-lapatinib-loaded F127 pluronic micelles.Q38735063
ABC transporters as mediators of drug resistance and contributors to cancer cell biology.Q38834784
Roles of the Bcl-2/Bax ratio, caspase-8 and 9 in resistance of breast cancer cells to paclitaxel.Q38942353
Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1.Q39863143
Human mutations that confer paclitaxel resistance.Q41769659
Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymersQ46968315
pH-triggered surface charge-switchable polymer micelles for the co-delivery of paclitaxel/disulfiram and overcoming multidrug resistance in cancerQ47104795
Polymeric micelles: Basic research to clinical practiceQ48667283
Efficacy and safety of trastuzumab, lapatinib, and paclitaxel neoadjuvant treatment with or without prolonged exposure to anti-HER2 therapy, and with or without hormone therapy for HER2-positive primary breast cancer: a randomised, five-arm, multiceQ49992953
Reconstituted high density lipoprotein mediated targeted co-delivery of HZ08 and paclitaxel enhances the efficacy of paclitaxel in multidrug-resistant MCF-7 breast cancer cells.Q50792703
Effect of polymer degradation on prolonged release of paclitaxel from filomicelles of polylactide/poly(ethylene glycol) block copolymers.Q52776519
Multidrug PLA-PEG filomicelles for concurrent delivery of anticancer drugs-The influence of drug-drug and drug-polymer interactions on drug loading and release properties.Q52862390
Lapatinib enhances the cytotoxic effects of doxorubicin in MCF-7 tumorspheres by inhibiting the drug efflux function of ABC transporters.Q53475159
Self-assembled filomicelles prepared from polylactide/poly(ethylene glycol) block copolymers for anticancer drug deliveryQ57182917
Liposomes as multicompartmental carriers for multidrug delivery in anticancer chemotherapyQ61697502
Dual-functionalized liposome by co-delivery of paclitaxel with sorafenib for synergistic antitumor efficacy and reversion of multidrug resistanceQ64106949
Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzymeQ72685142
Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8Q72710440
Paclitaxel- and lapatinib-loaded lipopolymer micelles overcome multidrug resistance in prostate cancerQ86952613
Bioresorbable filomicelles for targeted delivery of betulin derivative - In vitro studyQ90702218
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P921main subjectpaclitaxelQ423762
P577publication date2019-04-06
P1433published inPharmaceuticsQ27723332
P1476titleCytotoxic Effect of Paclitaxel and Lapatinib Co-Delivered in Polylactide-co-Poly(ethylene glycol) Micelles on HER-2-Negative Breast Cancer Cells
P478volume11

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