In vitro and in vivo evaluation of paclitaxel-lapatinib-loaded F127 pluronic micelles.

scientific article published on 31 October 2016

In vitro and in vivo evaluation of paclitaxel-lapatinib-loaded F127 pluronic micelles. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/03639045.2016.1254238
P698PubMed publication ID27796140

P50authorMahdi GholamiQ59684841
Maliheh SafaviQ60370722
P2093author name stringFarid Abedin Dorkoosh
Ebrahim Saadat
Fatemeh Ravar
Mahboobeh Pordeli
Pouya Dehghankelishadi
P2860cites workSolubilization of the novel anionic amphiphilic photosensitizer TPCS 2a by nonionic Pluronic block copolymersQ48880147
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Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenografts with docetaxel, flavopiridol, and 5-fluorouracil.Q53596582
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Can nanomedicines kill cancer stem cells?Q27022017
Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiersQ28282826
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Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a reviewQ29617388
Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers.Q30475533
A novel combined micellar system of lapatinib and Paclitaxel with enhanced antineoplastic effect against human epidermal growth factor receptor-2 positive breast tumor in vitroQ30871548
Somatostatin receptor-mediated tumor-targeting drug delivery using octreotide-PEG-deoxycholic acid conjugate-modified N-deoxycholic acid-O, N-hydroxyethylation chitosan micellesQ31065397
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)Q33194199
The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)-tocopheryl polyethylene glycol succinate nanoparticlesQ33237619
Targeted delivery of paclitaxel using folate-decorated poly(lactide)-vitamin E TPGS nanoparticlesQ33327252
Facilitated intracellular delivery of peptide-guided nanoparticles in tumor tissuesQ34219275
Pluronic block copolymers as novel polymer therapeutics for drug and gene deliveryQ34783697
Targeted poly (L-γ-glutamyl glutamine) nanoparticles of docetaxel against folate over-expressed breast cancer cells.Q35134791
Caveolae: mining little caves for new cancer targetsQ35190153
Pluronic F127 polymeric micelles for co-delivery of paclitaxel and lapatinib against metastatic breast cancer: preparation, optimization and in vitro evaluationQ35284749
Combination drug delivery approaches in metastatic breast cancerQ35955198
Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochoresQ36368107
Micellar nanocarriers: pharmaceutical perspectivesQ36655007
Preclinical evaluation of Genexol-PM, a nanoparticle formulation of paclitaxel, as a novel radiosensitizer for the treatment of non-small cell lung cancerQ37113921
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2Q37119716
Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cellsQ37263033
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A self-assembling nanoparticle for paclitaxel delivery in ovarian cancerQ37327582
The PKB/AKT pathway in cancerQ37705534
Incorporation of lapatinib into lipoprotein-like nanoparticles with enhanced water solubility and anti-tumor effect in breast cancerQ39186813
Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticlesQ39245832
Delivery of paclitaxel across cellular barriers using a dendrimer-based nanocarrier.Q39254937
Paclitaxel in tyrosine-derived nanospheres as a potential anti-cancer agent: in vivo evaluation of toxicity and efficacy in comparison with paclitaxel in CremophorQ39430827
A synergistic interaction between lapatinib and chemotherapy agents in a panel of cell lines is due to the inhibition of the efflux pump BCRP.Q39648670
Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo.Q39736030
Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel.Q39767302
Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines.Q39842390
Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cellsQ40321992
Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(ε-caprolactone) copolymer as a carrier for paclitaxelQ40649166
BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agentsQ43761469
Enhanced uptake and cytotoxity of folate-conjugated mitoxantrone-loaded micelles via receptor up-regulation by dexamethasoneQ45064323
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmicellesQ421110
P304page(s)390-398
P577publication date2016-11-14
P1433published inDrug Development and Industrial PharmacyQ5308840
P1476titleIn vitro and in vivo evaluation of paclitaxel-lapatinib-loaded F127 pluronic micelles
P478volume43

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cites work (P2860)
Q64998055Cytotoxic Effect of Paclitaxel and Lapatinib Co-Delivered in Polylactide-co-Poly(ethylene glycol) Micelles on HER-2-Negative Breast Cancer Cells.
Q89909885Evaluation of micelles incorporated into thermosensitive hydrogels for intratumoral delivery and controlled release of docetaxel: A dual approach for in situ treatment of tumors

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