mitogen-activated protein kinase 1

mammalian protein found in Homo sapiens

Wikidata entity: Q6590503



P682 biological process ... Q188941 (cell cycle) cell cycle
P682 biological process ... Q242736 (phosphorylation) phosphorylation
P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q332154 (ageing) ageing
P682 biological process ... Q411391 (regulation of gene expression) regulation of gene expression
P682 biological process ... Q471817 (development of the heart) development of the heart
P682 biological process ... Q658145 (chemotaxis) chemotaxis
P682 biological process ... Q1207365 (decidualization) decidualization
P682 biological process ... Q1805481 (long-term potentiation) long-term potentiation
P682 biological process ... Q2034716 (axon guidance) axon guidance
P682 biological process ... Q14911651 (neutrophil degranulation) neutrophil degranulation
P682 biological process ... Q14912098 (face development) face development
P682 biological process ... Q15317697 (cytosine metabolic process) cytosine metabolic process
P682 biological process ... Q15317702 (regulation of stress-activated MAPK cascade) regulation of stress-activated MAPK cascade
P682 biological process ... Q15317712 (regulation of cytoskeleton organization) regulation of cytoskeleton organization
P682 biological process ... Q15317715 (labyrinthine layer blood vessel development) labyrinthine layer blood vessel development
P682 biological process ... Q15317718 (response to epidermal growth factor) response to epidermal growth factor
P682 biological process ... Q15317722 (caveolin-mediated endocytosis) caveolin-mediated endocytosis
P682 biological process ... Q15317724 (regulation of Golgi inheritance) regulation of Golgi inheritance
P682 biological process ... Q15317727 (regulation of early endosome to late endosome transport) regulation of early endosome to late endosome transport
P682 biological process ... Q14599729 (response to estrogen) response to estrogen
P682 biological process ... Q14633883 (regulation of transcription, DNA-templated) regulation of transcription, DNA-templated
P682 biological process ... Q14633891 (positive regulation of cell population proliferation) positive regulation of cell population proliferation
P682 biological process ... Q14633893 (positive regulation of gene expression) positive regulation of gene expression
P682 biological process ... Q14758900 (MAPK cascade) MAPK cascade
P682 biological process ... Q14758919 (positive regulation of cell migration) positive regulation of cell migration
P682 biological process ... Q14763010 (transcription, DNA-templated) transcription, DNA-templated
P682 biological process ... Q21095195 (regulation of cellular response to heat) regulation of cellular response to heat
P682 biological process ... Q21097519 (regulation of cellular pH) regulation of cellular pH
P682 biological process ... Q21100616 (regulation of phosphatidylinositol 3-kinase signaling) regulation of phosphatidylinositol 3-kinase signaling
P682 biological process ... Q21100982 (cellular response to granulocyte macrophage colony-stimulating factor stimulus) cellular response to granulocyte macrophage colony-stimulating factor stimulus
P682 biological process ... Q21102118 (cellular response to amino acid starvation) cellular response to amino acid starvation
P682 biological process ... Q21104766 (positive regulation of telomerase activity) positive regulation of telomerase activity
P682 biological process ... Q21104771 (positive regulation of telomere maintenance via telomerase) positive regulation of telomere maintenance via telomerase
P682 biological process ... Q21106739 (cellular response to dopamine) cellular response to dopamine
P682 biological process ... Q21143508 (cardiac neural crest cell development involved in heart development) cardiac neural crest cell development involved in heart development
P682 biological process ... Q21202223 (positive regulation of telomere capping) positive regulation of telomere capping
P682 biological process ... Q14818018 (cellular response to DNA damage stimulus) cellular response to DNA damage stimulus
P682 biological process ... Q14818066 (positive regulation of transcription, DNA-templated) positive regulation of transcription, DNA-templated
P682 biological process ... Q14819467 (platelet activation) platelet activation
P682 biological process ... Q14819853 (learning or memory) learning or memory
P682 biological process ... Q2734305 (sensory perception of pain) sensory perception of pain
P682 biological process ... Q7251493 (protein phosphorylation) protein phosphorylation
P682 biological process ... Q14330653 (chemical synaptic transmission) chemical synaptic transmission
P682 biological process ... Q14330803 (response to toxic substance) response to toxic substance
P682 biological process ... Q14330834 (response to lipopolysaccharide) response to lipopolysaccharide
P682 biological process ... Q14819911 (response to stress) response to stress
P682 biological process ... Q14820066 (regulation of DNA-binding transcription factor activity) regulation of DNA-binding transcription factor activity
P682 biological process ... Q14820585 (growth hormone receptor signaling pathway via JAK-STAT) growth hormone receptor signaling pathway via JAK-STAT
P682 biological process ... Q14820592 (regulation of ossification) regulation of ossification
P682 biological process ... Q14820664 (response to nicotine) response to nicotine
P682 biological process ... Q14820681 (ERK1 and ERK2 cascade) ERK1 and ERK2 cascade
P682 biological process ... Q14821385 (positive regulation of peptidyl-threonine phosphorylation) positive regulation of peptidyl-threonine phosphorylation
P682 biological process ... Q14851952 (intracellular signal transduction) intracellular signal transduction
P682 biological process ... Q14851954 (positive regulation of protein import into nucleus) positive regulation of protein import into nucleus
P682 biological process ... Q14852005 (peptidyl-serine phosphorylation) peptidyl-serine phosphorylation
P682 biological process ... Q14859642 (stress-activated MAPK cascade) stress-activated MAPK cascade
P682 biological process ... Q14859939 (thyroid gland development) thyroid gland development
P682 biological process ... Q14859959 (negative regulation of cell differentiation) negative regulation of cell differentiation
P682 biological process ... Q14859964 (thymus development) thymus development
P682 biological process ... Q14859977 (Bergmann glial cell differentiation) Bergmann glial cell differentiation
P682 biological process ... Q14860204 (lung morphogenesis) lung morphogenesis
P682 biological process ... Q14599311 (apoptotic process) apoptotic process
P682 biological process ... Q14860826 (cellular response to organic substance) cellular response to organic substance
P682 biological process ... Q14861867 (diadenosine tetraphosphate biosynthetic process) diadenosine tetraphosphate biosynthetic process
P682 biological process ... Q14863363 (animal organ morphogenesis) animal organ morphogenesis
P682 biological process ... Q14863397 (peptidyl-threonine phosphorylation) peptidyl-threonine phosphorylation
P682 biological process ... Q14863403 (regulation of protein stability) regulation of protein stability
P682 biological process ... Q14863427 (B cell receptor signaling pathway) B cell receptor signaling pathway
P682 biological process ... Q14863968 (Fc-gamma receptor signaling pathway involved in phagocytosis) Fc-gamma receptor signaling pathway involved in phagocytosis
P682 biological process ... Q14863970 (T cell receptor signaling pathway) T cell receptor signaling pathway
P682 biological process ... Q14864218 (positive regulation of translation) positive regulation of translation
P682 biological process ... Q14864684 (fibroblast growth factor receptor signaling pathway) fibroblast growth factor receptor signaling pathway
P682 biological process ... Q14865169 (viral process) viral process
P682 biological process ... Q14865337 (positive regulation of cardiac muscle cell proliferation) positive regulation of cardiac muscle cell proliferation
P682 biological process ... Q14866222 (response to exogenous dsRNA) response to exogenous dsRNA
P682 biological process ... Q14874299 (Fc-epsilon receptor signaling pathway) Fc-epsilon receptor signaling pathway
P682 biological process ... Q14875882 (cellular response to tumor necrosis factor) cellular response to tumor necrosis factor
P682 biological process ... Q14882919 (cellular response to cadmium ion) cellular response to cadmium ion
P682 biological process ... Q14885627 (lipopolysaccharide-mediated signaling pathway) lipopolysaccharide-mediated signaling pathway
P682 biological process ... Q14902779 (trachea formation) trachea formation
P682 biological process ... Q14904955 (neural crest cell development) neural crest cell development
P682 biological process ... Q14905485 (ERBB signaling pathway) ERBB signaling pathway
P682 biological process ... Q14905565 (mammary gland epithelial cell proliferation) mammary gland epithelial cell proliferation
P682 biological process ... Q14906122 (cellular response to reactive oxygen species) cellular response to reactive oxygen species
P682 biological process ... Q14906415 (outer ear morphogenesis) outer ear morphogenesis
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q83181 (Golgi apparatus) Golgi apparatus
P681 cell component ... Q154626 (cytoskeleton) cytoskeleton
P681 cell component ... Q165291 (pseudopodium) pseudopodium
P681 cell component ... Q178999 (axon) axon
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q39572 (mitochondrion) mitochondrion
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q903634 (extracellular exosome) extracellular exosome
P681 cell component ... Q903644 (microtubule organizing center) microtubule organizing center
P681 cell component ... Q904514 (focal adhesion) focal adhesion
P681 cell component ... Q918594 (spindle) spindle
P681 cell component ... Q842429 (perikaryon) perikaryon
P681 cell component ... Q1051872 (caveola) caveola
P681 cell component ... Q14908513 (mitotic spindle) mitotic spindle
P681 cell component ... Q14645596 (extracellular region) extracellular region
P681 cell component ... Q21101057 (azurophil granule lumen) azurophil granule lumen
P681 cell component ... Q22325163 (protein-containing complex) protein-containing complex
P681 cell component ... Q22328083 (ficolin-1-rich granule lumen) ficolin-1-rich granule lumen
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q4374336 (postsynaptic density) postsynaptic density
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14860538 (early endosome) early endosome
P681 cell component ... Q14860539 (late endosome) late endosome
P681 cell component ... Q14864759 (dendrite cytoplasm) dendrite cytoplasm
P702 encoded by ... Q15317730 (MAPK1) MAPK1
P2888 exact match Url UniProt ???
P2888 exact match Url UniProt ???
P2888 exact match Url None ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P692 Gene Atlas image CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20MAPK1%20212271%20at.png ???
P527 has part(s) ... Q24768234 (protein kinase domain) protein kinase domain
P527 has part(s) ... Q24769051 (protein kinase, ATP binding site) protein kinase, ATP binding site
P527 has part(s) ... Q24777727 (mitogen-activated protein (MAP) kinase, conserved site) mitogen-activated protein (MAP) kinase, conserved site
P527 has part(s) ... Q24787419 (serine/threonine-protein kinase, active site) serine/threonine-protein kinase, active site
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14906671 (MAP kinase activity) MAP kinase activity
P680 molecular function ... Q14908036 (MAP kinase kinase activity) MAP kinase kinase activity
P680 molecular function ... Q14908084 (RNA polymerase II CTD heptapeptide repeat kinase activity) RNA polymerase II CTD heptapeptide repeat kinase activity
P680 molecular function ... Q14633858 (DNA binding) DNA binding
P680 molecular function ... Q14762994 (identical protein binding) identical protein binding
P680 molecular function ... Q14817981 (ATP binding) ATP binding
P680 molecular function ... Q14817982 (transcription factor binding) transcription factor binding
P680 molecular function ... Q14817984 (protein kinase binding) protein kinase binding
P680 molecular function ... Q14818104 (double-stranded DNA binding) double-stranded DNA binding
P680 molecular function ... Q14326094 (protein serine/threonine kinase activity) protein serine/threonine kinase activity
P680 molecular function ... Q14820641 (protein kinase activity) protein kinase activity
P680 molecular function ... Q14840131 (transferase activity) transferase activity
P680 molecular function ... Q14860365 (nucleotide binding) nucleotide binding
P680 molecular function ... Q14863082 (kinase activity) kinase activity
P680 molecular function ... Q14865333 (phosphatase binding) phosphatase binding
P680 molecular function ... Q14905186 (phosphotyrosine residue binding) phosphotyrosine residue binding
P680 molecular function ... Q14906652 (mitogen-activated protein kinase kinase kinase binding) mitogen-activated protein kinase kinase kinase binding
P361 part of ... Q24722147 (mitogen-activated protein (MAP) kinase, ERK1/2) mitogen-activated protein (MAP) kinase, ERK1/2
P361 part of ... Q24726164 (Protein kinase-like domain superfamily) Protein kinase-like domain superfamily
P361 part of ... Q83138186 (Protein kinase domain, protein family) Protein kinase domain, protein family
P361 part of ... Q95352334 (Mitogen-activated protein (MAP) kinase, conserved site, protein family) Mitogen-activated protein (MAP) kinase, conserved site, protein family
P361 part of ... Q95353644 (Serine/threonine-protein kinase, active site, protein family) Serine/threonine-protein kinase, active site, protein family
P361 part of ... Q95354221 (Protein kinase, ATP binding site, protein family) Protein kinase, ATP binding site, protein family
P129 physically interacts with ... Q27077782 (ravoxertinib) ravoxertinib
P129 physically interacts with ... Q27089081 (ulixertinib) ulixertinib

External Ids
P705Ensembl protein IDENSP00000381803
P705Ensembl protein IDENSP00000215832
P705Ensembl protein IDENSP00000440842
P486MeSH descriptor IDD019950
P672MeSH tree codeD08.811.913.696.620.682.700.567.249.500
P672MeSH tree codeD12.776.476.563.567.249.500
P638PDB structure ID4ZXT
P638PDB structure ID4FUX
P638PDB structure ID5BUI
P638PDB structure ID5BVD
P638PDB structure ID4QTA
P638PDB structure ID4N0S
P638PDB structure ID5AX3
P638PDB structure ID4G6O
P638PDB structure ID4ZZO
P638PDB structure ID4FUY
P638PDB structure ID4FV1
P638PDB structure ID5BUJ
P638PDB structure ID4QP6
P638PDB structure ID3SA0
P638PDB structure ID4FV3
P638PDB structure ID4QP1
P638PDB structure ID4FV0
P638PDB structure ID4QTE
P638PDB structure ID4G6N
P638PDB structure ID4QP7
P638PDB structure ID2OJI
P638PDB structure ID4XJ0
P638PDB structure ID3W55
P638PDB structure ID5BUE
P638PDB structure ID2Y9Q
P638PDB structure ID3D42
P638PDB structure ID4QP2
P638PDB structure ID4ZZM
P638PDB structure ID4QP4
P638PDB structure ID1PME
P638PDB structure ID5BVF
P638PDB structure ID4FV4
P638PDB structure ID4FV2
P638PDB structure ID4FV9
P638PDB structure ID4FV5
P638PDB structure ID1TVO
P638PDB structure ID4O6E
P638PDB structure ID3I5Z
P638PDB structure ID2OJG
P638PDB structure ID2OJJ
P638PDB structure ID4QP9
P638PDB structure ID4ZZN
P638PDB structure ID4QP8
P638PDB structure ID5BVE
P638PDB structure ID3I60
P638PDB structure ID4FV6
P638PDB structure ID4QPA
P638PDB structure ID4FV8
P638PDB structure ID4FV7
P638PDB structure ID5K4I
P638PDB structure ID1WZY
P638PDB structure ID4QP3
P638PDB structure ID3D44
P638PDB structure ID4H3P
P638PDB structure ID4H3Q
P638PDB structure ID4NIF
P638PDB structure ID4IZ5
P638PDB structure ID4IZA
P638PDB structure ID4FMQ
P638PDB structure ID3TEI
P638PDB structure ID4IZ7
P637RefSeq protein IDNP_002736
P637RefSeq protein IDNP_620407
P2892UMLS CUIC0170168
P352UniProt protein IDP28482

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