Phosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP(dAMP) kinase from L1210 cells

scientific article published on 01 November 1992

Phosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP(dAMP) kinase from L1210 cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0006-2952(92)90110-5
P698PubMed publication ID1449524

P50authorJindřich JindřichQ41258943
Miroslav OtmarQ56865486
P2093author name stringI Rosenberg
A Holý
I Votruba
A Merta
T Cihlár
T Y Herve
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectadenineQ15277
P304page(s)2067-2077
P577publication date1992-11-01
P1433published inBiochemical PharmacologyQ864229
P1476titlePhosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP(dAMP) kinase from L1210 cells
P478volume44

Reverse relations

cites work (P2860)
Q409409079-(2-Phosphonylmethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cpr-PMEDAP) as a prodrug of 9-(2-phosphonylmethoxyethyl)guanine (PMEG).
Q780548349-[2-(Phosphonomethoxy)ethyl]adenine diphosphate (PMEApp) as a substrate toward replicative DNA polymerases alpha, delta, epsilon, and epsilon*
Q34230702Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice
Q34464655Acyclic nucleoside phosphonates: a key class of antiviral drugs
Q41058515Acyclic nucleosides as antiviral compounds
Q41346811Analysis of inhibition of retroviral reverse transcriptase
Q40474589Anti-Retroviral and Pharmacological Properties of 9-(2-Phosphonylmethoxyethyl)Adenine (PMEA)
Q28379501Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected [...]
Q28379083Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine
Q34223779Antiviral treatment of chronic hepatitis B virus (HBV) infections
Q41915115Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand
Q35558801Clinical Potential of the Acyclic Nucleoside Phosphonates Cidofovir, Adefovir, and Tenofovir in Treatment of DNA Virus and Retrovirus Infections
Q33545117Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir
Q59285771Comparison of the disposition of ester prodrugs of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine [PMEA] in Caco-2 monolayers
Q33933498Development and optimization of anti-HIV nucleoside analogs and prodrugs: A review of their cellular pharmacology, structure-activity relationships and pharmacokinetics
Q28378681Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine
Q56786482Impact of 9-(2-phosphonylmethoxyethyl)adenine on (deoxy)ribonucleotide metabolism and nucleic acid synthesis in tumor cells
Q35375912In search of a selective antiviral chemotherapy.
Q21203584In vitro comparison of antiviral drugs against feline herpesvirus 1
Q39471425Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates
Q31660537Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymes
Q37083800Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase.
Q40672674Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives
Q28369617Perspectives for the treatment of hepatitis B virus infections
Q41049572Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl) adenine (PMEA).
Q73139890Synthesis of phosphonate derivatives of uridine, cytidine, and cytosine arabinoside
Q39778904Transport of 9-(2-phosphonomethoxyethyl)adenine across plasma membrane of HeLa S3 cells is protein mediated

Search more.