| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/0092-8674(88)90533-8 |
| P698 | PubMed publication ID | 3278811 |
| P50 | author | Jennifer Lippincott-Schwartz | Q6178547 |
| Juan S. Bonifacino | Q50726280 | ||
| P2093 | author name string | T Saito | |
| A M Weissman | |||
| J D Ashwell | |||
| R D Klausner | |||
| J J Sussman | |||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 85-95 | |
| P577 | publication date | 1988-01-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Failure to synthesize the T cell CD3-zeta chain: structure and function of a partial T cell receptor complex | |
| P478 | volume | 52 |
| Q36954754 | 1 Biochemistry and molecular genetics of Rh antigens |
| Q41676417 | A comparative analysis of alterations in protein expression after activation or human immunodeficiency virus, type 1 infection of human CD4+ T cells |
| Q37379671 | A conserved αβ transmembrane interface forms the core of a compact T-cell receptor-CD3 structure within the membrane |
| Q35891753 | A membrane-proximal tetracysteine motif contributes to assembly of CD3deltaepsilon and CD3gammaepsilon dimers with the T cell receptor. |
| Q52522639 | A motif within the T cell receptor alpha chain constant region connecting peptide domain controls antigen responsiveness. |
| Q41055757 | A novel 90-kDa tyrosine-phosphorylated protein associated with TCR complex in thymocytes |
| Q59057981 | A primitive immune system |
| Q33768882 | A specific defect in CD3 gamma-chain gene transcription results in loss of T-cell receptor/CD3 expression late after human immunodeficiency virus infection of a CD4+ T-cell line |
| Q37500218 | A subunit common to an IgG Fc receptor and the T-cell receptor mediates assembly through different interactions |
| Q37816649 | A view into the blind spot: solution NMR provides new insights into signal transduction across the lipid bilayer. |
| Q40875295 | Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine |
| Q42942951 | Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex |
| Q72370379 | Activation-induced proteolysis of cytoplasmic domain of zeta in T cell receptors and Fc receptors |
| Q36403254 | An orderly inactivation of intracellular retention signals controls surface expression of the T cell antigen receptor |
| Q61919142 | Analysis of tetanus toxin peptide/DR recognition by human T cell receptors reconstituted into a murine T cell hybridoma |
| Q37694110 | Antibodies against membrane interleukin 1 alpha activate accessory cells to stimulate proliferation of T lymphocytes |
| Q42769712 | Associations between subunit ectodomains promote T cell antigen receptor assembly and protect against degradation in the ER |
| Q33671547 | At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor |
| Q33887941 | Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody |
| Q33917824 | B lymphocyte antigen receptors (mIg) are non-covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex. |
| Q52317562 | BEST1 protein stability and degradation pathways differ between autosomal dominant Best disease and autosomal recessive bestrophinopathy accounting for the distinct retinal phenotypes. |
| Q35585626 | Basic residues in the T-cell receptor ζ cytoplasmic domain mediate membrane association and modulate signaling |
| Q41325460 | Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation |
| Q37622301 | CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney |
| Q28589169 | CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage |
| Q36843491 | CD3 zeta dependence of the CD2 pathway of activation in T lymphocytes and natural killer cells |
| Q68432723 | CD3-T cell receptor modulation is selectively induced in CD8 but not CD4 lymphocytes cultured in agar |
| Q39081204 | CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy |
| Q33750104 | Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy. |
| Q67656443 | Characterization of normal human CD3+ CD5- and γδ T cell receptor positive T lymphocytes |
| Q68429271 | Characterization of thymus-derived lymphocytes expressing Ti alpha-beta CD3 gamma delta epsilon zeta-zeta, Ti alpha-beta CD3 gamma delta epsilon eta-eta or Ti alpha-beta CD3 gamma delta epsilon zeta-zeta/zeta-eta antigen receptor isoforms: analysis |
| Q45984838 | Co-association of CD3 zeta with a receptor (CD16) for IgG Fc on human natural killer cells. |
| Q36981178 | Common themes in the assembly and architecture of activating immune receptors |
| Q24675239 | Comparison of human B cell antigen receptor complexes: membrane-expressed forms of immunoglobulin (Ig)M, IgD, and IgG are associated with structurally related heterodimers |
| Q36717167 | Control of T cell antigen reactivity via programmed TCR downregulation. |
| Q36304347 | Convergence on a distinctive assembly mechanism by unrelated families of activating immune receptors. |
| Q77355829 | Current views in intracellular transport: insights from studies in immunology |
| Q35541642 | Decreased expression of the CD3zeta chain in T cells infiltrating the synovial membrane of patients with osteoarthritis. |
| Q44051759 | Defective expression and tyrosine phosphorylation of the T cell receptor zeta chain in peripheral blood T cells from systemic lupus erythematosus patients |
| Q41729981 | Defects in signal transduction caused by a T cell receptor β chain substitution |
| Q34304147 | Deletion of the cytoplasmic region of the CD3 epsilon subunit does not prevent assembly of a functional T-cell receptor |
| Q35591730 | Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains |
| Q39759223 | Development of a flow cytometric co-immunoprecipitation technique for the study of multiple protein-protein interactions and its application to T-cell receptor analysis. |
| Q40874338 | Developmental and functional impairment of T cells in mice lacking CD3 zeta chains. |
| Q37636610 | Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells. |
| Q36363091 | Differential effects of zeta and eta transgenes on early alpha/beta T cell development |
| Q37500264 | Differential signal transduction via T-cell receptor CD3 zeta 2, CD3 zeta-eta, and CD3 eta 2 isoforms |
| Q38338088 | Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase. |
| Q48969830 | Ectopic expression of the immune adaptor protein CD3zeta in neural stem/progenitor cells disrupts cell-fate specification |
| Q41130056 | Effect of dexamethasone on T-cell receptor/CD3 expression |
| Q37367389 | Engagement of the natural killer cell IgG Fc receptor results in tyrosine phosphorylation of the zeta chain |
| Q77357578 | Evolution of T cell receptor (TCR) alpha beta heterodimer assembly with the CD3 complex |
| Q36690134 | Expression of T cell receptor βlocus in central nervous system neurons |
| Q77391549 | Expression of signal transducing T-cell receptor zeta molecules after adoptive immunotherapy in patients with gastric and colon cancer |
| Q37415170 | Expression of v-src in a murine T-cell hybridoma results in constitutive T-cell receptor phosphorylation and interleukin 2 production |
| Q35750844 | Facilitating matched pairing and expression of TCR chains introduced into human T cells |
| Q36954763 | Fc-gamma receptors: mediators, targets and markers of disease |
| Q41621169 | Functional reconstitution of an immunoglobulin antigen receptor in T cells |
| Q36853435 | Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection |
| Q41698128 | Genetic reconstitution of the T cell receptor (TcR) alpha/beta heterodimer restores the association of CD3 zeta 2 with the TcR/CD3 complex |
| Q55195444 | High frequency of cancer patients with abnormal assembly of the T cell receptor-CD3 complex in peripheral blood T lymphocytes. |
| Q37045978 | How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: the early history of ERAD. |
| Q68428818 | Human natural killer cells and mature T lymphocytes express identical CD3 zeta subunits as defined by cDNA cloning and sequence analysis |
| Q71118293 | Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity |
| Q68305955 | Immunodeficiency with low expression of the T cell receptor/CD3 complex. Effect on T lymphocyte activation |
| Q41114975 | Immunologic dysfunction in cancer |
| Q36380431 | In vitro translation and assembly of a complete T cell receptor-CD3 complex |
| Q36354126 | Induction of specific nonresponsiveness in unprimed human T cells by anti-CD3 antibody and alloantigen |
| Q26822514 | Infiltrating immune cells in the kidney in salt-sensitive hypertension and renal injury |
| Q43968748 | Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse |
| Q33791335 | Intimate association of Thy-1 and the T-cell antigen receptor with the CD45 tyrosine phosphatase |
| Q73316769 | Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells |
| Q42223573 | LAPTM5 promotes lysosomal degradation of intracellular CD3ζ but not of cell surface CD3ζ. |
| Q34318888 | Lack of Association of the CD247 SNP rs2056626 with Systemic Sclerosis in Han Chinese |
| Q27633054 | Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer |
| Q36578210 | Molecular Events Mediating T Cell Activation |
| Q35818930 | Molecular basis for the aberrant expression of T cell antigens in postthymic T cell malignancies |
| Q24299317 | Molecular biology and function of CD4 and CD8 |
| Q24642381 | Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex |
| Q33556260 | Molecular cloning of the CD3 eta subunit identifies a CD3 zeta-related product in thymus-derived cells |
| Q50335807 | Molecular components of the B-cell antigen receptor complex of the IgM class |
| Q35741512 | Molecular mechanisms for the assembly of the T cell receptor-CD3 complex. |
| Q44403491 | Mutational analysis of conserved amino acids in the T cell receptor alpha-chain transmembrane region: a critical role of leucine 112 and phenylalanine 127 for assembly and surface expression. |
| Q36400505 | Novel aspects of degradation of T cell receptor subunits from the endoplasmic reticulum (ER) in T cells: importance of oligosaccharide processing, ubiquitination, and proteasome-dependent removal from ER membranes |
| Q54289799 | Novel post-translational regulation of TCR expression in CD4+CD8+ thymocytes influenced by CD4. |
| Q36400745 | One of the CD3epsilon subunits within a T cell receptor complex lies in close proximity to the Cbeta FG loop |
| Q35867037 | OsHrd3 is necessary for maintaining the quality of endoplasmic reticulum-derived protein bodies in rice endosperm |
| Q36688308 | Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses |
| Q37635242 | Persistence of glucose residues on core oligosaccharides prevents association of TCR alpha and TCR beta proteins with calnexin and results specifically in accelerated degradation of nascent TCR alpha proteins within the endoplasmic reticulum |
| Q36220205 | Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly |
| Q41788651 | Preferential usage of the Fc receptor gamma chain in the T cell antigen receptor complex by gamma/delta T cells localized in epithelia |
| Q36366675 | Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis |
| Q35564863 | Quality Control and Protein Folding in the Secretory Pathway |
| Q57794693 | Rapid degradation of progressive ankylosis protein (ANKH) in craniometaphyseal dysplasia |
| Q40042916 | Rapid degradation of the heavy chain of class I major histocompatibility complex antigens in the endoplasmic reticulum of human cytomegalovirus-infected cells. |
| Q29615171 | Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER |
| Q38353770 | Redirected cytotoxic effector function. Requirements for expression of chimeric single chain high affinity immunoglobulin e receptors. |
| Q36230059 | Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3. |
| Q42831149 | Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro. |
| Q33784061 | Regulation of integrin function by T cell activation: points of convergence and divergence |
| Q33608649 | Role of the zeta chain in the expression of the T cell antigen receptor: genetic reconstitution studies |
| Q33899285 | Searching for significance in TCR-cytoskeleton interactions |
| Q36221069 | Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment |
| Q37420448 | Signals for retention of transmembrane proteins in the endoplasmic reticulum studied with CD4 truncation mutants |
| Q36757921 | Specific requirement for CD3epsilon in T cell development. |
| Q40646055 | Specificity and promiscuity in membrane helix interactions |
| Q40917234 | Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum |
| Q37961459 | Structure and function of the T cell antigen receptor |
| Q42767821 | Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex |
| Q36175254 | Subcellular localization of T-cell receptor complexes containing tyrosine-phosphorylated zeta proteins in immature CD4+CD8+ thymocytes |
| Q33648952 | Subunit interactions within the T-cell antigen receptor: clues from the study of partial complexes |
| Q35583489 | Surface T‐cell antigen receptor expression and availability for long‐term antigenic signaling |
| Q41760418 | Surface expression of CD3 in the absence of T cell receptor (TcR): evidence for sorting of partial TcR/CD3 complexes in a post-endoplasmic reticulum compartment |
| Q37631971 | Surface expression of alternative forms of the TCR/CD3 complex |
| Q44591651 | Sustained exposure to bacterial antigen induces interferon-γ-dependent T cell receptor ζ down-regulation and impaired T cell function |
| Q40995210 | Synthesis, assembly, and intracellular transport of the platelet glycoprotein Ib-IX-V complex |
| Q41826432 | Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory Genes |
| Q36377445 | Systemic T cell-independent tumor immunity after transplantation of universal receptor-modified bone marrow into SCID mice |
| Q72090378 | T Cell Development in Mice that Lack the ζ Chain of the T Cell Antigen Receptor Complex |
| Q56112105 | T Cell Receptor ζ Allows Stable Expression of Receptors Containing the CD3γ Leucine-based Receptor-sorting Motif |
| Q48073864 | T cell receptor iota an alternatively spliced product of the T cell receptor zeta gene. |
| Q36161506 | T cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha |
| Q42043122 | T cells from late tumor-bearing mice express normal levels of p56lck, p59fyn, ZAP-70, and CD3 zeta despite suppressed cytolytic activity |
| Q35751012 | T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex. |
| Q37603731 | T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins. |
| Q37092026 | T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor |
| Q40944084 | TCR kappa, a new splicing of the murine TCR zeta gene locus, is modulated by glucocorticoid treatment |
| Q35924790 | TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues |
| Q37628748 | Targeted disruption within the CD3 zeta/eta/phi/Oct-1 locus in mouse |
| Q37258802 | Targeting of the T-cell receptor zeta-chain gene in embryonic stem cells: strategies for generating multiple mutations in a single gene |
| Q42941998 | The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation |
| Q46633340 | The CD3 delta gene encodes multiple transcripts regulated by transcriptional and post-transcriptional mechanisms |
| Q24561517 | The CD3-gamma and CD3-delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes |
| Q33888549 | The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages |
| Q36231744 | The CD45 tyrosine phosphatase regulates phosphotyrosine homeostasis and its loss reveals a novel pattern of late T cell receptor-induced Ca2+ oscillations |
| Q28214721 | The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor |
| Q40501505 | The Stalk Domain of NKp30 Contributes to Ligand Binding and Signaling of a Preassembled NKp30-CD3ζ Complex. |
| Q38314688 | The T-cell receptor zeta chain contains two homologous domains with which simian immunodeficiency virus Nef interacts and mediates down-modulation |
| Q30813588 | The assembly of diverse immune receptors is focused on a polar membrane-embedded interaction site |
| Q24567493 | The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species |
| Q41168173 | The cytoplasmic tail of FcgammaRIIIAalpha is involved in signaling by the low affinity receptor for immunoglobulin G. |
| Q41531903 | The cytoplasmic tail of the T cell receptor zeta chain is dispensable for antigen-mediated T cell activation |
| Q37215710 | The discovery of a reciprocal relationship between tyrosine-kinase signaling and cullin neddylation |
| Q33842336 | The gamma and epsilon subunits of the CD3 complex inhibit pre-Golgi degradation of newly synthesized T cell antigen receptors |
| Q44777598 | The high affinity Fc epsilon receptor gamma subunit (Fc epsilon RI gamma) facilitates T cell receptor expression and antigen/major histocompatibility complex-driven signaling in the absence of CD3 zeta and CD3 eta |
| Q36355748 | The lysine residue in the membrane-spanning domain of the beta chain is necessary for cell surface expression of the T cell antigen receptor |
| Q28507085 | The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line |
| Q46185462 | The mouse CD3-gamma, -delta, and -epsilon genes reside within 50 kilobases on chromosome 9, whereas CD3-zeta maps to chromosome 1, band H. |
| Q34167740 | The organizing principle in the formation of the T cell receptor-CD3 complex. |
| Q24307955 | The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor |
| Q24291295 | The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain |
| Q70055686 | The transmembrane orientation of the epsilon chain of the TcR/CD3 complex |
| Q42079880 | The uptake of 3H-labelled monodeoxyfluoro-myo-inositols into thymocytes and their incorporation into phospholipid in permeabilized cells |
| Q67862538 | Thymocyte Activation and Death: a Mechanism for Molding the T Cell Repertoire |
| Q33938341 | Transmembrane helical interactions: zeta chain dimerization and functional association with the T cell antigen receptor |
| Q45271549 | Unique ζ-chain motifs mediate a direct TCR-actin linkage critical for immunological synapse formation and T-cell activation |
| Q24294340 | ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain |
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