T cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha

scholarly article

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T cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2004PNAS..101.1696C
P356DOI10.1073/PNAS.0308231100
P932PMC publication ID341820
P698PubMed publication ID14745016
P5875ResearchGate publication ID8901658

P50authorAndrew P CopeQ61091985
P2093author name stringYuti Chernajovsky
Joanna M Clark
Manvinder Panesar
Pia Isomäki
Alexander E Annenkov
P2860cites workDisplacement of linker for activation of T cells from the plasma membrane due to redox balance alterations results in hyporesponsiveness of synovial fluid T lymphocytes in rheumatoid arthritisQ73407127
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Loss of original antigenic specificity in T cell hybridomas transduced with a chimeric receptor containing single-chain Fv of an anti-collagen antibody and Fc epsilonRI-signaling gamma subunitQ77716012
The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chainQ24291295
T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membraneQ24319819
A new subunit of the human T-cell antigen receptor complexQ28116587
Signal transduction by lymphocyte antigen receptorsQ29619894
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Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritisQ34229344
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunityQ34334817
Effect of Redox Balance Alterations on Cellular Localization of LAT and Downstream T-Cell Receptor Signaling PathwaysQ34440097
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Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signalingQ36377176
HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progressionQ37359597
Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chainQ37380253
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T cell signaling abnormalities in systemic lupus erythematosus are associated with increased mutations/polymorphisms and splice variants of T cell receptor zeta chain messenger RNA.Q38299911
New simplified molecular design for functional T cell receptorQ38317949
Mutations in T cell Receptor ζ Chain mRNA of Peripheral T cells from Systemic Lupus Erythematosus PatientsQ38331633
Highly efficient gene transfer into antigen-specific primary mouse lymphocytes with replication-deficient retrovirus expressing the 10A1 envelope proteinQ40740227
Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.Q40806098
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On the dynamics of TCR:CD3 complex cell surface expression and downmodulationQ40837872
Rapid turnover of the CD3 zeta chain independent of the TCR-CD3 complex in normal T cellsQ41337209
Serial triggering of many T-cell receptors by a few peptide-MHC complexesQ41346263
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.Q41643996
T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 allelesQ41678690
Defective production of functional 98-kDa form of Elf-1 is responsible for the decreased expression of TCR zeta-chain in patients with systemic lupus erythematosusQ42527692
Regulation of T cell receptor CD3zeta chain expression by L-arginineQ43957769
Granzyme B-mediated degradation of T-cell receptor zeta chain.Q44123678
Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zetaQ45867388
Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritisQ46376254
Molecular cloning of the zeta chain of the T cell antigen receptorQ48328718
TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelinationQ54150165
Antigen receptor tail clue.Q55060334
Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor SignalingQ57275521
Defective TCR-mediated signaling in synovial T cells in rheumatoid arthritisQ63406972
Alterations in signal transduction molecules in T lymphocytes from tumor-bearing miceQ67966175
Failure to synthesize the T cell CD3-zeta chain: structure and function of a partial T cell receptor complexQ68128126
Identification of the receptor for antigen and major histocompatibility complex on human inducer T lymphocytesQ70998073
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1696-1701
P577publication date2004-01-26
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleT cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha
P478volume101

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cites work (P2860)
Q34027578Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus.
Q33686997ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis
Q36786805Genomic expression profiling of TNF-alpha-treated BDC2.5 diabetogenic CD4+ T cells
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Q58204959Molecular abnormalities of T-cells in systemic lupus erythematosus
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Q54438066TNFRI is a positive T-cell costimulatory molecule important for the timing of cytokine responses.
Q37696172The serum protein profile of early parity which induces protection against breast cancer.
Q36292657What does tumour necrosis factor excess do to the immune system long term?

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