The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.

scientific article published on January 1992

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0092-8674(92)90208-T
P8608Fatcat IDrelease_sdyjivtbzbd5vicuv5gfs7rtyu
P698PubMed publication ID1531041

P50authorFrancois LetourneurQ67277623
Bernard MalissenQ2898273
P2093author name stringF Luton
T Brocker
A Hoeveler
A M Wegener
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)83-95
P577publication date1992-01-01
P1433published inCellQ655814
P1476titleThe T cell receptor/CD3 complex is composed of at least two autonomous transduction modules
P478volume68

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cites work (P2860)
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Q36363567Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation
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Q28144872Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31
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Q39564545Dipeptidyl‐peptidase IV/CD26 on T cells: analysis of an alternative T‐cell activation pathway
Q34137693Direct evidence to support the immunosurveillance concept in a human regressive melanoma
Q41361558Distinct domains of the CD3-gamma chain are involved in surface expression and function of the T cell antigen receptor
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Q57275587Double-negative thymocyte subsets in CD3′ chain-deficient mice: Absence of HSA+CD44−CD25− cells
Q40485228Dual antigen recognition by B cells
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Q33889480Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
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Q30493782Evidence for a functional sidedness to the alphabetaTCR.
Q41315792Evidence for multivalent structure of T-cell antigen receptor complex
Q77357578Evolution of T cell receptor (TCR) α β heterodimer assembly with the CD3 complex
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Q41102972Functions of TCR and pre-TCR subunits: lessons from gene ablation
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Q24658051T cell activation
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Q41529750T cell receptor (TCR) beta chain homodimers on the surface of immature but not mature alpha, gamma, delta chain deficient T cell lines
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Q24319819T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane
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Q24680262T cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T)
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Q68202781T lymphocyte anergy during acute infectious mononucleosis is restricted to the clonotypic receptor activation pathway
Q52200529T lymphocyte development in the absence of Fc epsilon receptor I gamma subunit: analysis of thymic-dependent and independent alpha beta and gamma delta pathways
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Q35557286T-cell receptor signal transmission: who gives an ITAM?
Q54023030T-cell regulation. Tails of phosphorylation and T-cell activation
Q41126119T-lymphocyte development and function in gene-targeted mutant mice
Q41514626TCR zeta chain in T cell development and selection
Q36364437TCR/CD3 coupling to Fas-based cytotoxicity
Q28513949Targeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct-1 transcription on the opposite strand
Q37258802Targeting of the T-cell receptor zeta-chain gene in embryonic stem cells: strategies for generating multiple mutations in a single gene
Q34064895The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events
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Q30010025The Adaptor Protein SAP Directly Associates with CD3ζ Chain and Regulates T Cell Receptor Signaling
Q40402665The B cell antigen receptor complex: mechanisms and implications of tyrosine kinase activation
Q40833882The B-cell antigen receptor: structure and function of primary, secondary, tertiary and quaternary components
Q42941998The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation
Q40356478The CD3 gamma epsilon/delta epsilon signaling module provides normal T cell functions in the absence of the TCR zeta immunoreceptor tyrosine-based activation motifs
Q30500933The CD3 ζ Subunit Contains a Phosphoinositide-Binding Motif That Is Required for the Stable Accumulation of TCR–CD3 Complex at the Immunological Synapse
Q40942972The CD3-gamma delta epsilon transducing module mediates CD38-induced protein-tyrosine kinase and mitogen-activated protein kinase activation in Jurkat T cells.
Q35076682The Ras/MAPK cascade and the control of positive selection
Q72086491The T cell receptor associated CD3-epsilon protein is phosphorylated upon T cell activation in the two tyrosine residues of a conserved signal transduction motif
Q39564552The T-cell receptor associated zeta-chain is required but not sufficient for CD26 (dipeptidylpeptidase IV) mediated signaling
Q41475945The V beta complementarity determining region 1 of a major histocompatibility complex (MHC) class I-restricted T cell receptor is involved in the recognition of peptide/MHC I and superantigen/MHC II complex
Q36365409The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion
Q41168173The cytoplasmic tail of FcgammaRIIIAalpha is involved in signaling by the low affinity receptor for immunoglobulin G.
Q41531903The cytoplasmic tail of the T cell receptor zeta chain is dispensable for antigen-mediated T cell activation
Q39255555The cytoplasmic tail of the T cell receptor zeta chain is required for signaling via CD26.
Q70764565The effect of detergent selection on retinal outer segment A280/A500 ratios
Q35076675The formation and functions of the 21- and 23-kDa tyrosine-phosphorylated TCR zeta subunits
Q36731606The gamma chain of the high-affinity receptor for IgE is a major functional subunit of the T-cell antigen receptor complex in gamma delta T lymphocytes
Q58659242The glycosylphosphatidylinositol-anchored CD59 protein stimulates both T cell receptor ζ/ZAP-70-dependent and -independent signaling pathways in T cells
Q53477973The influence of LFA 1 on human T cells stimulated by solid-phase immobilized HLA class II-peptide complexes
Q36365496The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit
Q37677539The right team at the right time to go for a home run: tyrosine kinase activation by the TCR.
Q41682334The role of CD45 and CD45‐associated molecules in T cell activation
Q40801710The role of p56lck and p59fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection
Q36376819The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex
Q24291295The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain
Q39564539The transmembrane region of CD2‐associated signal‐transducing proteins is crucial for the outcome of CD2‐mediated T‐cell activation
Q40913094Thy-1/CD3 coengagement promotes TCR signaling and enhances particularly tyrosine phosphorylation of the raft molecule LAT.
Q38578530Thymocyte selection in Vav and IRF-1 gene-deficient mice
Q40553796Transgenic TCR expression: comparison of single chain with full-length receptor constructs for T-cell function.
Q28277768Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association
Q38342816Tyrosine Phosphorylation of the CD3-ε Subunit of the T Cell Antigen Receptor Mediates Enhanced Association with Phosphatidylinositol 3-Kinase in Jurkat T Cells
Q40791215Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways
Q41613221Tyrosine-containing motif that transduces cell activation signals also determines internalization and antigen presentation via type III receptors for IgG
Q24306545ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity
Q24294340ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
Q38355898Zinc-binding sites in the N terminus of Mycoplasma arthritidis-derived mitogen permit the dimer formation required for high affinity binding to HLA-DR and for T cell activation
Q36706391p59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain

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