Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins

scientific article published on January 1996

Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0065-3233(08)60487-8
P698PubMed publication ID8908296

P2093author name stringEisen HN
Tsomides TJ
Sykulev Y
P2860cites workZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chainQ24294340
Structure of the human class I histocompatibility antigen, HLA-A2Q24297966
A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chainsQ24301420
The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptidesQ24339477
Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejectionQ24561706
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytesQ24653345
A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomasQ24679739
The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibodyQ24683570
Crystal structures of two viral peptides in complex with murine MHC class I H-2KbQ27642080
Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognitionQ27642083
Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middleQ27642184
Specificity pockets for the side chains of peptide antigens in HLA-Aw68Q27700642
The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selectionQ27729346
The antigenic identity of peptide-MHC complexes: A comparison of the conformations of five viral peptides presented by HLA-A2Q27729917
Crystal structure of the beta chain of a T cell antigen receptorQ27729924
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptideQ27731272
Bound water molecules and conformational stabilization help mediate an antigen-antibody associationQ27731557
Affinity maturation leads to differential expression of multiple copies of a κ light-chain transgeneQ60065187
Expression of two T cell receptor alpha chains: dual receptor T cellsQ61268447
Emerging principles for the recognition of peptide antigens by MHC class I moleculesQ67494475
Exact prediction of a natural T cell epitopeQ67702861
Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligandQ67903498
Antibody framework residues affecting the conformation of the hypervariable loopsQ68092016
Heterodimeric, disulfide-linked alpha/beta T cell receptors in solutionQ68291793
Why affinity progression of antibodies during immune responses is probably not accompanied by parallel changes in the immunoglobulin-like antigen-specific receptors on T cellsQ68810655
Three-dimensional structure of an antigen-antibody complex at 2.8 A resolutionQ68969863
Enhanced recognition of a modified peptide antigen by cytotoxic T cells specific for influenza nucleoproteinQ69018238
Molecular mimicry and autoimmune diseaseQ69205630
Selective induction of growth factor production and growth factor receptor expression by different signals to a single T cellQ69377330
Antigen stimulation of cytolytic T lymphocyte precursors: minimal requirements for growth and acquisition of cytolytic activityQ69872017
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell responseQ71169443
Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergyQ71988127
An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance inductionQ72105874
T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificityQ72112177
Allelic exclusion of alpha chains in TCRsQ72189651
Antigenic peptide binding by class I and class II histocompatibility proteinsQ72192298
Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexesQ72628246
TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selectiveQ72873502
Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytesQ37580704
An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I proteinQ37644137
Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytesQ37680808
Phospholipids enhance the binding of peptides to class II major histocompatibility moleculesQ37707645
Genetic and mutational analysis of the T-cell antigen receptorQ37925514
Antibody-antigen complexesQ37943232
T cell receptor gene diversity and selectionQ37943233
The basis for the immunoregulatory role of macrophages and other accessory cellsQ38174608
Antigen recognition by class I-restricted T lymphocytesQ38201551
Acquisition of immunologic self-toleranceQ38254157
Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenicsQ38330987
Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancyQ38624477
Implications of a Fab-like structure for the T-cell receptorQ38666499
The role of the CD28 receptor during T cell responses to antigenQ28263234
Presentation of viral antigen controlled by a gene in the major histocompatibility complexQ28285937
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolutionQ28287140
Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinaseQ28298958
Sequence analysis of peptides bound to MHC class II moleculesQ28303686
Structure of the gene of tum- transplantation antigen P91A: the mutated exon encodes a peptide recognized with Ld by cytolytic T cellsQ28512984
T cell receptor antagonist peptides induce positive selectionQ29618820
T-cell antigen receptor genes and T-cell recognitionQ29619721
Signal transduction by lymphocyte antigen receptorsQ29619894
Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domainsQ30195771
Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-AdQ30311282
Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometryQ30434686
HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentationQ30434689
Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.Q30463850
Association of the fyn protein-tyrosine kinase with the T-cell antigen receptorQ33620349
The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytesQ33637736
Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target moleculeQ33676045
Structure of the T-cell antigen receptor: evidence for two CD3 epsilon subunits in the T-cell receptor-CD3 complexQ33800570
Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic proteinQ34293468
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.Q34350288
HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptidesQ34372218
Kinetic and affinity limits on antibodies produced during immune responsesQ34598643
Crystal structure of an HIV-binding recombinant fragment of human CD4.Q34637157
Cell interactions between histoincompatible T and B lymphocytes. The H-2 gene complex determines successful physiologic lymphocyte interactionsQ34733830
T cells with two functional antigen-specific receptorsQ34756338
Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopesQ35093159
Proteolysis, proteasomes and antigen presentationQ35228583
Regulation of TCR alpha and beta gene allelic exclusion during T-cell developmentQ35232298
A molecular model of MHC class-I-restricted antigen processingQ35347353
Cell biology of antigen processing and presentation to major histocompatibility complex class I molecule-restricted T lymphocytesQ35533657
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chainsQ35588811
CD8+ T lymphocytes of African green monkeys secrete an immunodeficiency virus-suppressing lymphokineQ35621878
High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteinsQ35918289
Short-lived complexes between myelin basic protein peptides and IAkQ35985828
Affinity and the immune responseQ47781047
Locus-specific somatic hypermutation in germinal centre T cellsQ48077130
Correlations between T-cell specificity and the structure of the antigen receptorQ48365072
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences.Q48389926
Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytesQ48533870
Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic miceQ50800754
Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificityQ51133242
Another view of the selective model of thymocyte selectionQ51142565
Positive and negative selection of an antigen receptor on T cells in transgenic miceQ52249517
Identification of a CD4 binding site on the beta 2 domain of HLA-DR moleculesQ52443678
A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytesQ52538972
Cellular peptide composition governed by major histocompatibility complex class I moleculesQ53885926
Particle counting by flow cytometry can determine intrinsic equilibrium constants for antibody-ligand interactions in solutionQ54015447
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC moleculesQ55042699
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.Q55061347
The mouse T cell receptor: structural heterogeneity of molecules of normal T cells defined by xenoantiserumQ56872851
The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptidesQ56889076
Real-time measurement of antigenic peptide binding to empty and preloaded single-chain major histocompatibility complex class I moleculesQ56941840
Isolation and characterization of antigen-la complexes involved in T cell recognitionQ57000170
CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytesQ57040021
Molecular basis of antigen mimicry by an anti-idiotopeQ58670679
Specific antigen—la activation of transfected human T cells expressing murine Ti αβ —human T3 receptor complexesQ58967140
Isolation of cDNA clones encoding T cell-specific membrane-associated proteinsQ59067678
Identification of self peptides bound to purified HLA-B27Q59068162
CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinomaQ59069991
Binding of immunogenic peptides to Ia histocompatibility moleculesQ59070314
Association of class I major histocompatibility heavy and light chains induced by viral peptidesQ59072754
A role for peptide in determining MHC class II structureQ59077345
Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cellQ59077649
Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cellsQ59078526
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigensQ59092174
Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in sizeQ39229154
Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c.Q39288171
Alpha beta lineage-specific expression of the alpha T cell receptor gene by nearby silencersQ39521572
A hypothetical model of the foreign antigen binding site of class II histocompatibility moleculesQ39623507
Role of hydrophobicity in the binding of coenzymes. Appendix. Translational and rotational contribution to the free energy of dissociationQ40176970
The human T-cell receptorQ40216296
The B7 and CD28 receptor familiesQ40392461
The ups and downs of T cell costimulationQ40398747
Generation, translocation, and presentation of MHC class I-restricted peptidesQ40422033
Tumor antigens recognized by T lymphocytesQ40661131
T-cell inhibition of humoral responsiveness. II. Theory on the role of restrictive recognition in immune regulationQ40690063
Positive selection of lymphocytesQ40807424
The biochemistry and cell biology of antigen processing and presentationQ40898211
T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinasesQ40898871
Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses.Q41030813
The outline structure of the T-cell alpha beta receptor.Q41094902
T-cell-receptor affinity and thymocyte positive selectionQ41192128
Serial triggering of many T-cell receptors by a few peptide-MHC complexesQ41346263
Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonistsQ41379043
Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activityQ41440548
A cytotoxic T lymphocyte clone can recognize the same naturally occurring self peptide in association with a self and nonself class I MHC proteinQ41443366
MHC class II function preserved by low-affinity peptide interactions preceding stable bindingQ41447819
Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assaysQ41450491
Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cellsQ41461980
Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variantsQ41462011
Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytesQ41483867
A quantitative assay to measure the interaction between immunogenic peptides and purified class I major histocompatibility complex moleculesQ41489222
Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cellsQ41532466
Antigen processing mutant T2 cells present viral antigen restricted through H-2KbQ41535379
Transporter-independent processing of HIV-1 envelope protein for recognition by CD8+ T cellsQ41542329
Stoichiometric labeling of peptides by iodination on tyrosyl or histidyl residuesQ41561181
Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptorQ41628039
The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptideQ41640226
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.Q41643996
Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.Q41644187
Low Affinity Interaction of Peptide-MHC Complexes with T Cell ReceptorsQ41652382
On the nature of peptides involved in T cell alloreactivityQ41657428
Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysisQ41675478
Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporterQ41683715
Peptide selection by MHC class I moleculesQ41687117
The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathwaysQ41691499
The role of beta 2-microglobulin in peptide binding by class I moleculesQ41710947
Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb moleculeQ41714857
The minimal number of class II MHC-antigen complexes needed for T cell activationQ41724410
Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.Q41725161
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulationQ41725217
Empty MHC class I molecules come out in the coldQ41725383
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic routeQ41737562
Limit of T cell tolerance to self proteins by peptide presentationQ41739980
The kinetics of antibody binding to membrane antigens in solution and at the cell surfaceQ41982863
Kinetic maturation of an immune responseQ42018143
Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecastQ42087769
Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complexQ42936415
A kinetic intermediate in the reaction of an antigenic peptide and I-EkQ43440073
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytesQ44462817
Characterization of Naturally Occurring Minor Histocompatibility Peptides Including H-4 and H-YQ44514515
The binding affinity and dissociation rates of peptides for class I major histocompatibility complex moleculesQ44625079
Transfer of specificity by murine alpha and beta T-cell receptor genesQ44774041
Autologous peptides constitutively occupy the antigen binding site on Ia.Q44907850
Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cellsQ45007765
Evidence for a differential avidity model of T cell selection in the thymusQ45155438
Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptorQ45986774
A locus control region in the T cell receptor alpha/delta locusQ46057798
A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonistsQ46121537
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytesQ46197161
Effects of peptide length and composition on binding to an empty class I MHC heterodimerQ46340241
Direct binding of influenza peptides to class I HLA moleculesQ46490144
Characterization of a naturally processed MHC class II-restricted T-cell determinant of hen egg lysozymeQ46739108
Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.Q46778527
Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsivenessQ36009049
Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysisQ36230273
Allelic exclusion at DNA rearrangement level is required to prevent coexpression of two distinct T cell receptor beta genesQ36230452
Endogenous peptides of a soluble major histocompatibility complex class I molecule, H-2Lds: sequence motif, quantitative binding, and molecular modeling of the complexQ36232156
Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antiseraQ36247967
Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytesQ36272607
The strange cross-reaction of menadione (vitamin K3) and 2,4-dinitrophenyl ligands with a myeloma protein and some conventional antibodiesQ36273220
Histocompatibility antigen-activated cytotoxic T lymphocytes. II. Estimates of the frequency and specificity of precursorsQ36335542
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognitionQ36344766
A clone-specific monoclonal antibody that inhibits cytolysis of a cytolytic T cell cloneQ36347595
In vitro cell-mediated immune responses to the male specific(H-Y) antigen in miceQ36358603
The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigensQ36358831
High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte responseQ36361251
Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signalingQ36361605
Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cellsQ36361774
Expression of two alpha chains on the surface of T cells in T cell receptor transgenic miceQ36362577
Peptide length and sequence specificity of the mouse TAP1/TAP2 translocatorQ36362717
Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptorQ36363264
Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytesQ36363449
Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chainsQ36363495
Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1Q36363763
Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytesQ36364266
A third type of murine T-cell receptor geneQ36613724
A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell cloneQ36699072
Solution binding of an antigenic peptide to a major histocompatibility complex class I molecule and the role of beta 2-microglobulinQ36890441
Kinetics of protein-protein association explained by Brownian dynamics computer simulationQ36949476
Quantitation of reversible binding by particle counting: hapten-antibody interaction as a model systemQ37024416
Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-AkQ37147375
Crawling movements of lymphocytes on and beneath fibroblasts in cultureQ37334000
Interactions between immunogenic peptides and MHC proteinsQ37357891
Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenesQ37436836
Kinetics of antigenic peptide binding to the class II major histocompatibility molecule I-AdQ37519795
Alloreactive T cells discriminate among a diverse set of endogenous peptidesQ37530676
P304page(s)1-56
P577publication date1996-01-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inAdvances in Protein ChemistryQ15756442
P1476titleAntigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins
P478volume49

Reverse relations

cites work (P2860)
Q35101815A model T-cell receptor system for studying memory T-cell development
Q47733735A mutant human β2-microglobulin can be used to generate diverse multimeric class I peptide complexes as specific probes for T cell receptors
Q74545050Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition
Q33731073Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization
Q33720544Binding energetics of T-cell receptors: correlation with immunological consequences
Q40628580Broadly Increased Sensitivity to Cytotoxic T Lymphocytes Resulting from Nef Epitope Escape Mutations
Q41574270Characteristics of the intrahepatic cytotoxic T lymphocyte response in chronic hepatitis C virus infection
Q40663321Chimeric immune receptor T cells bypass class I requirements and recognize multiple cell types relevant in HIV-1 infection
Q40151758Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells
Q27639247Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design
Q27639768Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL
Q37308343Cutting edge: TLR ligands increase TCR triggering by slowing peptide-MHC class I decay rates
Q36370382Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes
Q34478717Development of CD4+ T cells expressing a nominally MHC class I-restricted T cell receptor by two different mechanisms.
Q34099738Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor
Q39654323Early T-cell activation biophysics.
Q36367702Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing
Q44255903Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex
Q74286685Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR
Q34056465Immunopathogenesis of HIV-1 infection
Q30861962In vitro evolution of a T cell receptor with high affinity for peptide/MHC.
Q36380627Initiation Codon Scanthrough versus Termination Codon Readthrough Demonstrates Strong Potential for Major Histocompatibility Complex Class I–restricted Cryptic Epitope Expression
Q38093572Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.
Q39682548Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes
Q40996486Peptide antagonism and T cell receptor interactions with peptide-MHC complexes
Q47817942Quantitative aspects of T-cell recognition: from within the antigen-presenting cell to within the T cell
Q36368381Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes
Q35691052Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes
Q33655849Strategies to genetically engineer T cells for cancer immunotherapy
Q27758459Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes
Q77158682Structural principles that govern the peptide-binding motifs of class I MHC molecules
Q37823023T Cell Receptor Signaling Kinetics Takes the Stage
Q33935247T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.
Q30873107TCRs with high affinity for foreign pMHC show self-reactivity
Q34956078The T-cell response in patients with cancer
Q33351448The effect of mutations on the alloreactive T cell receptor/peptide-MHC interface structure: a molecular dynamics study
Q33737674The impact of TCR-binding properties and antigen presentation format on T cell responsiveness
Q35941639The regulation and maturation of antiviral immune responses
Q40895891The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules

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