Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation

scientific article published on 01 June 1990

Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/CLPT.1990.94
P698PubMed publication ID2357863

P2093author name stringD M Roden
A J Wood
H H Zhou
L B Anthony
P433issue6
P304page(s)686-693
P577publication date1990-06-01
P1433published inClinical Pharmacology & TherapeuticsQ1101529
P1476titleQuinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation
P478volume47

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cites work (P2860)
Q34122414Antiarrhythmic agents: drug interactions of clinical significance
Q35570981Antihypertensive therapy: special focus on drug interactions
Q41619585Clinical pharmacokinetic considerations in the elderly. An update
Q40712419Clinical significance of genetic influences on cardiovascular drug metabolism
Q28071256Drug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trials
Q37268522Ethnic differences in drug disposition and responsiveness
Q43554154Food increases the bioavailability of tolterodine but not effective exposure
Q40832404Genetically determined adverse drug reactions involving metabolism
Q38773640Incorporation of the Time-Varying Postprandial Increase in Splanchnic Blood Flow into a PBPK Model to Predict the Effect of Food on the Pharmacokinetics of Orally Administered High-Extraction Drugs.
Q90700101Influence of Cytochrome P450 2D6 Polymorphisms on the Efficacy of Oral Propranolol in Treating Infantile Hemangioma
Q73511084Inhibition of CYP2D6 by quinidine and its effects on the metabolism of cilostazol
Q36923318Metabolites of antihypertensive drugs. An updated review of their clinical pharmacokinetic and therapeutic implications
Q51579932Pharmacokinetic and pharmacodynamic interactions between diltiazem and quinidine.
Q47404372Pharmacokinetics of CYP2C9, CYP2C19, and CYP2D6 substrates in healthy Chinese and European subjects.
Q41598967Pharmacological importance of stereochemical resolution of enantiomeric drugs
Q37611786Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.
Q70493631Similar effect of oxidation deficiency (debrisoquine polymorphism) and quinidine on the apparent volume of distribution of (+/-)-metoprolol
Q40858967Stereoselective and isozyme-selective drug interactions
Q41940518Stereoselective genetically-determined interaction between chronic flecainide and quinidine in patients with arrhythmias
Q71455359Stereoselective pharmacokinetics of [14C]-labeled KE-298, a new anti-rheumatic drug, in rats
Q77647233The contribution of the enzymes CYP2D6 and CYP2C19 in the demethylation of artemether in healthy subjects
Q72113275The effect of zileuton on antipyrine and indocyanine green disposition*
Q41959654Topical timolol for treatment of epistaxis in hereditary haemorrhagic telangiectasia associated with bradycardia: a look at CYP2D6 metabolising variants
Q36851934Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
Q40999769beta-blockers. Drug interactions of clinical significance

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