The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist

scientific article published on 01 July 1988

The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID2454923

P2093author name stringImoto Y
Codina J
Hamilton SL
Birnbaumer L
Brown AM
Yatani A
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)9887-9895
P577publication date1988-07-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist
P478volume263

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cites work (P2860)
Q72104441A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of beta-adrenergic and dihydropyridine agonists
Q70674232Abundant Gs alpha mRNA in basket cells of the dentate gyrus in adult rat hippocampus
Q37044207Activation of protein kinase A-independent pathways by Gs alpha in Drosophila
Q83009924Adrenergic and cholinergic activation of calcium signals in cultured postnatal skeletal myocytes of the rat
Q71918858Alterations in inotropy, nitric oxide and cyclic GMP synthesis, protein phosphorylation and ADP-ribosylation in the endotoxin-treated rat myocardium and cardiomyocytes
Q33683081Antiserum raised against residues 159-168 of the guanine nucleotide-binding protein Gi3-alpha reacts with ependymal cells and some neurons in the rat brain containing cholecystokinin- or cholecystokinin- and tyrosine 3-hydroxylase-like immunoreactiv
Q37577537Biotechnology of beta-adrenergic receptors
Q68252404Ca2+ channel currents in rat sensory neurones: interaction between guanine nucleotides, cyclic AMP and Ca2+ channel ligands
Q36226788Calcium influx mediated by the Escherichia coli heat-stable enterotoxin B (STB)
Q41201963Cellular distribution and biochemical characterization of G proteins in skeletal muscle: comparative location with voltage-dependent calcium channels
Q68076326Charge movement and calcium currents in skeletal muscle fibers are enhanced by GTP gamma S
Q35817358Cholera toxin inhibits signal transduction by several mitogens and the in vitro growth of human small-cell lung cancer
Q42802866Cholera toxin treatment produces down-regulation of the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs).
Q34577351Decreased bioactivity of the guanine nucleotide-binding protein that stimulates adenylate cyclase in hearts from cardiomyopathic Syrian hamsters
Q34088036Dihydropyridine-sensitive skeletal muscle Ca channels in polarized planar bilayers. 2. Effects of phosphorylation by cAMP-dependent protein kinase
Q35780239Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets.
Q28585315Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse
Q46597144Effect of isoprenaline on Ca2+ channel current in single smooth muscle cells isolated from taenia of the guinea-pig caecum
Q68136345Endothelin activates voltage-dependent Ca2+ current by a G protein-dependent mechanism in rabbit cardiac myocytes
Q67715216Excitation-contraction coupling in skeletal muscle fibres of rat and toad in the presence of GTP gamma S
Q28118683G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates
Q24537396G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels
Q68238536GTP ? causes contraction of skinned frog skeletal muscle via the DHP-sensitive Ca2+ channels of sealed T-tubules
Q36434575GTP-dependent regulation of myometrial KCa channels incorporated into lipid bilayers
Q28343965Genetic analysis of the Drosophila Gs(alpha) gene
Q41993885Glucocorticoids modulate mRNA levels for G-protein beta-subunits
Q42836453Guanine-nucleotide-binding proteins Gi and Gs in fat-cells from normal, hypothyroid and obese human subjects
Q44718204Influence of beta-adrenergic stimulation on the fast sodium current in the intact rat papillary muscle
Q42148601Inhibition of mink lung epithelial cell proliferation by transforming growth factor-beta is coupled through a pertussis-toxin-sensitive substrate
Q36410389Internal and external effects of dihydropyridines in the calcium channel of skeletal muscle
Q70472222Isoproterenol and GTP gamma S inhibit L-type calcium channels of differentiating rat skeletal muscle cells
Q72832728Isoproterenol modulates the calcium channels through two different mechanisms in smooth-muscle cells from rabbit portal vein
Q41464028Kinetic properties of skeletal-muscle-like high-threshold calcium currents in a non-fusing muscle cell line
Q37864920Left ventricular dilatation and failure post-myocardial infarction: pathophysiology and possible pharmacologic interventions
Q41714534Mobilization of extracellular Ca2+ by prostaglandin F2 alpha can be modulated by fluoride in 3T3-L1 fibroblasts
Q41717271Multiple conductance levels of the dihydropyridine-sensitive calcium channel in GH3 cells
Q90478901Neurohumoral Control of Sinoatrial Node Activity and Heart Rate: Insight From Experimental Models and Findings From Humans
Q36410325Nonmodal gating of cardiac calcium channels as revealed by dihydropyridines
Q67488836Novel suppression of an L‐type calcium channel in neurones of murine dorsal root ganglia by 2,3‐butanedione monoxime
Q37205783Occurrence of the alpha subunits of G proteins in cerebral cortex synaptic membrane and postsynaptic density fractions: modulation of ADP-ribosylation by Ca2+/calmodulin
Q68330730Pharmacological characteristics of adenosine-induced inhibition of dog ventricular contractility: dependence on the pre-existing level of ?-adrenoceptor activation
Q24527341Phosphorylation of elongation factor 2 during Ca(2+)-mediated secretion from rat parotid acini
Q43027230Rapid adaptation of cardiac ryanodine receptors: modulation by Mg2+ and phosphorylation
Q68330725Regional differences of beta 1- and beta 2-adrenoceptor-mediated functions in feline heart. A beta 2-adrenoceptor-mediated positive inotropic effect possibly unrelated to cyclic AMP
Q40242883Regulation of the cardiac L-type calcium channel in L6 cells by arginine-vasopressin
Q46160854Role of the GTP-binding protein Gs in the ?-adrenergic modulation of cardiac Ca channels
Q36411629Single calcium channel behavior in native skeletal muscle
Q37306892Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteins
Q67488108Stimulatory guanine nucleotide-binding protein and adenylate cyclase activities in Bio 14.6 cardiomyopathic hamsters at the hypertrophic stage
Q36076341Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology
Q37165427The GNAS Locus: Quintessential Complex Gene Encoding Gsalpha, XLalphas, and other Imprinted Transcripts
Q36329859The effects of beta-adrenoceptor activation on contraction in isolated fast- and slow-twitch skeletal muscle fibres of the rat.
Q42836747Transforming growth factor beta 1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s).
Q28378633Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation
Q36410758Voltage-dependent inactivation of T-tubular skeletal calcium channels in planar lipid bilayers
Q24561617Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase
Q55054560Whole-cell calcium current in guinea-pig ventricular myocytes dialysed with guanine nucleotides.

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