| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.8456312 |
| P698 | PubMed publication ID | 8456312 |
| P2093 | author name string | C J Marshall | |
| P2860 | cites work | Retinal degeneration in choroideremia: deficiency of rab geranylgeranyl transferase | Q24313609 |
| P433 | issue | 5103 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | protein-protein interaction | Q896177 |
| P304 | page(s) | 1865-1866 | |
| P577 | publication date | 1993-03-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Protein prenylation: a mediator of protein-protein interactions | |
| P478 | volume | 259 |
| Q71999589 | 11 Effects of prenyl modifications on interactions of small G proteins with regulators |
| Q52509128 | 18 Prenylcysteine analogs to study function of carboxylmethylation in signal transduction |
| Q37624332 | A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium |
| Q41910073 | A large pheromone and receptor gene complex determines multiple B mating type specificities in Coprinus cinereus. |
| Q34282925 | A mechanism for posttranslational modifications of proteins by yeast protein farnesyltransferase |
| Q73171126 | Activation of the cholesterol pathway and Ras maturation in response to stress |
| Q39523324 | Acylation of Escherichia coli hemolysin: a unique protein lipidation mechanism underlying toxin function. |
| Q36774645 | Acylation stabilizes a protease-resistant conformation of protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides |
| Q35126517 | Alendronate (ALN) combined with osteoprotegerin (OPG) significantly improves mechanical properties of long bone than the single use of ALN or OPG in the ovariectomized rats |
| Q63345653 | Analogs of farnesylcysteine induce apoptosis in HL-60 cells |
| Q42837129 | Assembly and intracellular targeting of the betagamma subunits of heterotrimeric G proteins |
| Q36139997 | Atorvastatin inhibits pancreatic carcinogenesis and increases survival in LSL-KrasG12D-LSL-Trp53R172H-Pdx1-Cre mice |
| Q35851202 | Biological activity of human immunodeficiency virus type 1 Vif requires membrane targeting by C-terminal basic domains |
| Q33697467 | Bisphosphonates: from the laboratory to the clinic and back again |
| Q36864487 | Calcium causes a conformational change in lamin A tail domain that promotes farnesyl-mediated membrane association |
| Q28290534 | Characterization of HDJ-2, a human 40 kD heat shock protein |
| Q42828257 | Characterization of Rheb functions using yeast and mammalian systems |
| Q28564158 | Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope |
| Q22010883 | Cloning, expression, and cellular localization of a human prenylcysteine lyase |
| Q28585843 | Cloning, expression, and characterization of a novel guanylate-binding protein, GBP3 in murine erythroid progenitor cells |
| Q24522454 | Clostridium difficile toxins: mechanism of action and role in disease |
| Q37395840 | Context-dependent substrate recognition by protein farnesyltransferase. |
| Q27622014 | Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution |
| Q28271260 | Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras |
| Q41418106 | Determinants for intracellular sorting of cytoplasmic and nuclear intermediate filaments |
| Q71823618 | Efficient Interaction with a Receptor Requires a Specific Type of Prenyl Group on the G Protein γ Subunit |
| Q47251070 | Efficient farnesylation of an extended C-terminal C(x)3X sequence motif expands the scope of the prenylated proteome. |
| Q42832101 | Evidence for a high affinity, saturable, prenylation-dependent p21Ha-ras binding site in plasma membranes |
| Q77863815 | Evidence for covalent attachment of diphytanylglyceryl phosphate to the cell-surface glycoprotein of Halobacterium halobium |
| Q38288609 | Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity |
| Q30421452 | Expansion of protein farnesyltransferase specificity using "tunable" active site interactions: development of bioengineered prenylation pathways. |
| Q37355259 | Farnesyl analogues inhibit vasoconstriction in animal and human arteries |
| Q36008675 | Flexibility of ras lipid modifications studied by 2H solid-state NMR and molecular dynamics simulations |
| Q28344059 | Function of the farnesyl moiety in visual signalling |
| Q36669959 | Fungal lipopeptide mating pheromones: a model system for the study of protein prenylation |
| Q48541892 | G protein beta1gamma2 subunits promote microtubule assembly |
| Q30468687 | G protein gamma subunits with altered prenylation sequences are properly modified when expressed in Sf9 cells |
| Q41083765 | Generation of self-clusters of galectin-1 in the farnesyl-bound form |
| Q36234981 | Genetics, prevention and screening for melanoma. |
| Q42666048 | Geranylgeranyl pyrophosphate synthase encoded by the newly isolated gene GGPS6 from Arabidopsis thaliana is localized in mitochondria |
| Q51762739 | Getting a handle on protein prenylation. |
| Q24550941 | Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences |
| Q33335624 | Identification and functional expression in yeast of a prenylcysteine alpha-carboxyl methyltransferase gene from Arabidopsis thaliana |
| Q31036394 | Identification of a novel class of farnesylation targets by structure-based modeling of binding specificity |
| Q33514156 | Identification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivities |
| Q73067677 | In vitro assay and characterization of the farnesylation-dependent prelamin A endoprotease |
| Q38056497 | Inhibition of GTRAP3-18 may increase neuroprotective glutathione (GSH) synthesis |
| Q35944601 | Inhibition of Ras for cancer treatment: the search continues |
| Q40837781 | Inhibition of farnesyltransferase increases TGFbeta type II receptor expression and enhances the responsiveness of human cancer cells to TGFbeta. |
| Q71701948 | Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets |
| Q24806404 | Interaction Between Mevalonate Pathway and Retinoic Acid-Induced Differentiation |
| Q42395667 | Interaction of the C-terminal region of the Ggamma protein with model membranes. |
| Q64241016 | Intracellular Vesicle Trafficking Genes, -GTP, Are Highly Expressed Under Salinity and Rapid Dehydration but Down-Regulated by Drought in Leaves of Chickpea ( L.) |
| Q38291153 | Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor |
| Q24310310 | Isolation and characterization of a prenylcysteine lyase from bovine brain |
| Q36633321 | Isoprenylation masks a conformational epitope and enhances trans-dominant inhibitory function of the large hepatitis delta antigen |
| Q40048765 | Isoprenylation mediates direct protein-protein interactions between hepatitis large delta antigen and hepatitis B virus surface antigen. |
| Q24310039 | KSR, a novel protein kinase required for RAS signal transduction |
| Q93108340 | Lipid Modifications in Cilia Biology |
| Q24309425 | Lipid modifications of trimeric G proteins |
| Q36234532 | Localization of a heterotrimeric G protein gamma subunit to focal adhesions and associated stress fibers |
| Q44062588 | Lovastatin potentiates antitumor activity of doxorubicin in murine melanoma via an apoptosis-dependent mechanism |
| Q38274079 | Manumycin inhibits ras signal transduction pathway and induces apoptosis in COLO320-DM human colon tumour cells. |
| Q33895715 | Mechanobiology and the microcirculation: cellular, nuclear and fluid mechanics |
| Q40857389 | Membrane association and targeting of prenylated Ras-like GTPases |
| Q37476804 | Microarray analysis of retinal gene expression in Egr-1 knockout mice. |
| Q46101450 | Molecular and biochemical characterization of tomato farnesyl-protein transferase |
| Q33632255 | Molecular mechanisms of action of bisphosphonates. |
| Q37415239 | Multifunctional prenylated peptides for live cell analysis |
| Q36137487 | Multiple post-translational modifications affect heterologous protein synthesis |
| Q27937744 | Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins |
| Q39091745 | N-Acetylglutaminoyl-S-farnesyl-L-cysteine (SIG-1191): an anti-inflammatory molecule that increases the expression of the aquaglyceroporin, aquaporin-3, in human keratinocytes |
| Q24297481 | Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1 |
| Q39416839 | Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma |
| Q35875247 | Phosphorylation of the hepatitis delta virus antigens |
| Q74700006 | Potentiated antitumour effects of cisplatin and lovastatin against MmB16 melanoma in mice |
| Q22010630 | Prenylated prelamin A interacts with Narf, a novel nuclear protein |
| Q27935638 | Prenylation of Saccharomyces cerevisiae Chs4p Affects Chitin Synthase III activity and chitin chain length |
| Q42833741 | Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking |
| Q28140543 | Prenylation-dependent association of protein-tyrosine phosphatases PRL-1, -2, and -3 with the plasma membrane and the early endosome |
| Q95437844 | Prenylcysteine alpha-carboxyl methyltransferase in suspension-cultured tobacco cells |
| Q36278104 | Primary structure of a photoactive yellow protein from the phototrophic bacterium Ectothiorhodospira halophila, with evidence for the mass and the binding site of the chromophore |
| Q89996102 | Protein Farnesyltransferase Catalyzes Unanticipated Farnesylation and Geranylgeranylation of Shortened Target Sequences |
| Q33745380 | Protein farnesylation in plants: a greasy tale |
| Q58842619 | Protein farnesyltransferase from Trypanosoma brucei. A heterodimer of 61- and 65-kda subunits as a new target for antiparasite therapeutics |
| Q48057194 | Protein farnesyltransferase in plants: molecular characterization and involvement in cell cycle control |
| Q89577058 | Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action |
| Q24320032 | RIC, a calmodulin-binding Ras-like GTPase |
| Q24564075 | Ras membrane targeting is essential for glucose signaling but not for viability in yeast |
| Q36786557 | Ras-Raf interaction: two-hybrid analysis |
| Q41260833 | Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins |
| Q90664456 | Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1 |
| Q40403027 | Rho as a regulator of the cytoskeleton. |
| Q24309268 | Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins |
| Q30305912 | Role of C-terminal domains of the G protein beta subunit in the activation of effectors. |
| Q42819416 | Role of GTP Binding, Isoprenylation, and the C-Terminal α-Helices in the Inhibition of Cell Spreading by the Interferon-Induced GTPase, Mouse Guanylate-Binding Protein-2 |
| Q43648841 | Selection and identification of Singapore grouper iridovirus vaccine candidate antigens using bioinformatics and DNA vaccination |
| Q41294243 | Selective Inhibition of Ras-dependent Cell Growth by Farnesylthiosalisylic Acid |
| Q48042496 | Sequence analysis of a 24-kb contiguous genomic region at the Arabidopsis thaliana PFL locus on chromosome 1. |
| Q47837052 | Sequence analysis of a 40-kb Arabidopsis thaliana genomic region located at the top of chromosome 1. |
| Q48223316 | Serum cholesterol in cerebral malignancies |
| Q40872114 | Signal transduction pathways and their relevance in human astrocytomas |
| Q57098883 | Solid-state NMR characterization of the putative membrane anchor of TWD1 from Arabidopsis thaliana |
| Q83324479 | Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch |
| Q35224159 | Spreading of differentiating human monocytes is associated with a major increase in membrane-bound CDC42. |
| Q78123021 | Stimulation of neutrophils by prenylcysteine analogs: Ca(2+) release and influx |
| Q41291044 | Structure and function of proteins in G-protein-coupled signal transfer |
| Q36626506 | Subcellular localization of the Vif protein of human immunodeficiency virus type 1. |
| Q73106204 | Synthesis and evaluation of homofarnesoyl-substituted CAAX-peptidomimetics as farnesyltransferase inhibitors and antiproliferative agents |
| Q37795722 | Synthesis, Modification and Turnover of Proteins during Aging |
| Q41239231 | Targeting signal transduction in the discovery of antiproliferative drugs |
| Q49032663 | The Farnesyl Group of H-Ras Facilitates the Activation of a Soluble Upstream Activator of Mitogen-activated Protein Kinase |
| Q92572483 | The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood-testis barrier and results in hypospermatogenesis |
| Q24805139 | The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution |
| Q37818303 | The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase |
| Q77343239 | The p21-Ras signal transduction pathway and growth regulation in human high-grade gliomas |
| Q41645806 | The prenylation status of a novel plant calmodulin directs plasma membrane or nuclear localization of the protein |
| Q39550784 | Unique properties of the large antigen of hepatitis delta virus. |
| Q39582249 | Use of a prenylation inhibitor as a novel antiviral agent. |
| Q36300246 | Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 and -7-dependent. |
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