Comparative study on human pharmacokinetics of activated ifosfamide and cyclophosphamide by a modified fluorometric test

scientific article published on 01 January 1981

Comparative study on human pharmacokinetics of activated ifosfamide and cyclophosphamide by a modified fluorometric test is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00405906
P953full work available at URLhttp://link.springer.com/content/pdf/10.1007/BF00405906.pdf
http://link.springer.com/article/10.1007/BF00405906/fulltext.html
http://link.springer.com/content/pdf/10.1007/BF00405906
P698PubMed publication ID7240346

P2093author name stringG. Voelcker
H. J. Hohorst
T. Wagner
D. Heydrich
T. Jork
P2860cites workpharmacologistQ2114605
[Studies on the spontaneous decomposition of 4-hydroxyphosphamide and 4-hydroperoxyphosphamide by means of thin-layer chromatography]Q68941328
Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivoQ69551574
[Blood level and urinary excretion of activated cyclophosphamide and its deactivation products in man (author's transl)]Q71143704
Fluorometric determination of acrolein and related compounds with m-aminophenolQ72290253
Fluorometric determination of "activated" cyclophosphamide and ifosfamide in blood (author's transl)Q28327626
Cyclophosphamide cystitis—Identification of acrolein as the causative agentQ28327805
Mass spectrometric characterization of activated N-(2-chloroethyl)amino oxazaphosphorine derivativeQ28333075
Synthesis of 4-hydroperoxy derivatives of ifosfamide and trofosfamide by direct ozonation and preliminary antitumor evaluation in vivoQ28333815
Studies on the human pharmacokinetics of isophosphamide (NSC-109724)Q28342614
Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamideQ39687321
Permeation of cyclophosphamide (NSC-26271) metabolites into tumor cellsQ43535151
Deactivation of cyclophosphamide (NSC-26271) metabolites by sulfhydryl compoundsQ44523073
Isolation and mass spectral identification of blood metabolities of cyclophosphamide: Evidence for phosphoramide mustard as the biologically active metaboliteQ66931110
Identification of aldophosphamide as a metabolite of cyclophosphamide in vitro and in vivo in humansQ67585033
Characterization and quantitative estimation of activated cyclophosphamide in blood and urineQ67585038
Comparative pharmacologic study in vitro and in vivo with cyclophosphamide (NSC-26271), cyclophosphamide metabolites, and plain nitrogen mustard compoundsQ67796446
The problem of oncostatic specificity of cyclophosphamide (NSC-26271): Studies on reactions that control the alkylating and cytotoxic activityQ67796451
Studies on 4-hydroperoxycyclophosphamide (NSC-181815): a simple preparation method and its application for the synthesis of a new class of "activated" sulfur-containing cyclophosphamide (NSC-26271) derivativesQ67796489
Studies on the metabolism of isopnosphamide (NSC-109724) in manQ67796495
Studies on the clinical pharmacology and toxicology of isophosphamide (NSC-109724)Q67796499
Isolation and characterisation of two main metabolites of ifosfamide from human urine (author's transl)Q68298984
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
cancer researchQ3421914
ifosfamideQ418560
oncologyQ162555
P304page(s)95-104
P577publication date1981-01-01
P1433published inJournal of Cancer Research and Clinical OncologyQ2081599
P1476titleComparative study on human pharmacokinetics of activated ifosfamide and cyclophosphamide by a modified fluorometric test
P478volume100

Reverse relations

cites work (P2860)
Q67864961Ambulatory high-dose 5-day continuous-infusion ifosfamide combination chemotherapy in advanced solid tumors: a feasibility study
Q69428484Analysis of 4-hydroxycyclophosphamide by gas chromatography-mass spectrometry in plasma
Q39533747Clinical pharmacokinetics of drugs used in the treatment of breast cancer
Q39757762Comparative activity of ifosfamide and cyclophosphamide
Q70589461Comparative effects of ASTA Z 7557 (INN mafosfamide) and cyclophosphamide on hematopoiesis in mice
Q72678270Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde, and 2- and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy
Q55478651Determination of 4-hydroxyifosfamide in biological matrices by high-performance liquid chromatography.
Q42537311Determination of acrolein in human urine by headspace gas chromatography and mass spectrometry.
Q34584039Dosing and side-effects of ifosfamide plus mesna
Q72822733Effect of ASTA Z 7557 (INN mafosfamide) a precursor of 4-hydroxy-cyclophosphamide on human T-lymphocytes' Fc-receptors and immunoregulatory functions
Q34726639Ifosfamide clinical pharmacokinetics
Q28324157Ifosfamide/mesna. A review of its antineoplastic activity, pharmacokinetic properties and therapeutic efficacy in cancer
Q36419989In vivo detection of ifosfamide by 31P-MRS in rat tumours: increased uptake and cytotoxicity induced by carbogen breathing in GH3 prolactinomas
Q44054408Influence of mesna and cysteine on the systemic toxicity and therapeutic efficacy of activated cyclophosphamide
Q67864968Metabolism and pharmacokinetics of oral and intravenous ifosfamide
Q44455488Non-myeloablative hematopoietic stem cell transplantation for the treatment of adult T-cell lymphoma in a patient with advanced hepatic impairment
Q55242390Pharmacokinetic approach to rational therapeutic doses for human tumor-bearing nude mice.
Q45000857Pharmacokinetics and metabolism of cyclophosphamide administered after total body irradiation of bone marrow transplant recipients
Q46467130Preclinical pharmacokinetics and stability of isophosphoramide mustard
Q72032372Quantitation of 4-hydroxycyclophosphamide/aldophosphamide in whole blood
Q68202674Repeated high-dose cyclophosphamide administration in bone marrow transplantation: exposure to activated metabolites
Q34630267The effect of age on the pharmacokinetics of ifosfamide
Q68801422The effect of route of administration and fractionation of dose on the metabolism of ifosfamide
Q41478818Toxicity of ifosfamide, cyclophosphamide and their metabolites in renal tubular cells in culture

Search more.