| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0092-8674(00)80977-0 |
| P698 | PubMed publication ID | 8565068 |
| P2093 | author name string | N Kleckner | |
| S Bolland | |||
| P2860 | cites work | A general two-metal-ion mechanism for catalytic RNA | Q24562157 |
| Rapid and efficient site-specific mutagenesis without phenotypic selection | Q27860608 | ||
| Genetic evidence that Tn10 transposes by a nonreplicative mechanism | Q28287295 | ||
| Metal ion catalysis in the Tetrahymena ribozyme reaction | Q29036095 | ||
| Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism | Q29616775 | ||
| Structural domains of IS10 transposase and reconstitution of transposition activity from proteolytic fragments lacking an interdomain linker | Q33959910 | ||
| The two single-strand cleavages at each end of Tn10 occur in a specific order during transposition | Q34009809 | ||
| The mechanism of transposition of Tc3 in C. elegans. | Q34325150 | ||
| Transpositional recombination: mechanistic insights from studies of mu and other elements | Q35231355 | ||
| Identification of residues in the Mu transposase essential for catalysis | Q35589106 | ||
| Single amino acid substitutions uncouple the DNA binding and strand scission activities of Fok I endonuclease. | Q36601344 | ||
| Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases | Q36815395 | ||
| Excision of Tn10 from the donor site during transposition occurs by flush double-strand cleavages at the transposon termini | Q37021318 | ||
| Identification and characterization of a pre-cleavage synaptic complex that is an early intermediate in Tn10 transposition | Q37622400 | ||
| Initiation of V(D)J recombination in a cell-free system. | Q38294240 | ||
| Function and structure relationships in DNA polymerases | Q40394926 | ||
| DNA transposition: from a black box to a color monitor | Q40939354 | ||
| P element transposition in vitro proceeds by a cut-and-paste mechanism and uses GTP as a cofactor. | Q41629918 | ||
| Tn7 transposition in vitro proceeds through an excised transposon intermediate generated by staggered breaks in DNA. | Q41765684 | ||
| The IS4 family of insertion sequences: evidence for a conserved transposase motif | Q42694238 | ||
| Tn7 transposition: target DNA recognition is mediated by multiple Tn7-encoded proteins in a purified in vitro system | Q44919190 | ||
| Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism | Q45829846 | ||
| High-frequency P element loss in Drosophila is homolog dependent. | Q52449709 | ||
| Kinetic and structural analysis of a cleaved donor intermediate and a strand transfer intermediate in Tn10 transposition. | Q54701850 | ||
| DNA cleavage in trans by the active site tyrosine during Flp recombination: Switching protein partners before exchanging strands | Q58923847 | ||
| Transpososomes: Stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA | Q61827050 | ||
| A specific class of IS10 transposase mutants are blocked for target site interactions and promote formation of an excised transposon fragment | Q64390107 | ||
| HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer | Q67802014 | ||
| Division of labor among monomers within the Mu transposase tetramer | Q70471720 | ||
| Complete transposition requires four active monomers in the mu transposase tetramer | Q72801077 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 223-233 | |
| P577 | publication date | 1996-01-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site | |
| P478 | volume | 84 |
| Q24540071 | A highly conserved domain of the maize activator transposase is involved in dimerization |
| Q42009798 | A hyperactive transposase of the maize transposable element activator (Ac) |
| Q47114521 | A single active site in the mariner transposase cleaves DNA strands of opposite polarity. |
| Q51803328 | Amino acid residues in Rag1 crucial for DNA hairpin formation. |
| Q42501406 | Architecture of the Tn7 posttransposition complex: an elaborate nucleoprotein structure |
| Q35970972 | Control of transposase activity within a transpososome by the configuration of the flanking DNA segment of the transposon |
| Q33887759 | Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking |
| Q34124977 | DDE transposases: Structural similarity and diversity |
| Q33652023 | DNA hairpin opening mediated by the RAG1 and RAG2 proteins |
| Q33958242 | Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking |
| Q73306193 | Domain III function of Mu transposase analysed by directed placement of subunits within the transpososome |
| Q47411271 | Excision of the Drosophila mariner transposon Mos1. Comparison with bacterial transposition and V(D)J recombination |
| Q42095907 | Factors responsible for target site selection in Tn10 transposition: a role for the DDE motif in target DNA capture. |
| Q74473323 | Functional characterization of the Tn5 transposase by limited proteolysis |
| Q33968558 | Functional organization of single and paired V(D)J cleavage complexes |
| Q37569830 | Gene therapy vectors: the prospects and potentials of the cut-and-paste transposons |
| Q73279858 | Hairpin formation in Tn5 transposition |
| Q39447196 | IHF modulation of Tn10 transposition: sensory transduction of supercoiling status via a proposed protein/DNA molecular spring |
| Q39647872 | IHF-independent assembly of the Tn10 strand transfer transpososome: implications for inhibition of disintegration |
| Q41077328 | IS10/Tn10 transposition efficiently accommodates diverse transposon end configurations |
| Q77489081 | IS231A transposition: conservative versus replicative pathway |
| Q52081212 | Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex. |
| Q74293115 | Identification of two topologically independent domains in RAG1 and their role in macromolecular interactions relevant to V(D)J recombination |
| Q29617579 | Insertion sequences |
| Q40429974 | Isolation and characterization of Tn7 transposase gain-of-function mutants: a model for transposase activation |
| Q38536147 | Mechanisms of DNA Transposition |
| Q74251258 | Mechanisms of metal ion action in Tn10 transposition |
| Q71032193 | Mu transpositional recombination: donor DNA cleavage and strand transfer in trans by the Mu transposase |
| Q41065107 | Multiple roles for divalent metal ions in DNA transposition: distinct stages of Tn10 transposition have different Mg2+ requirements |
| Q35210006 | Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination |
| Q34279162 | Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinase |
| Q34641788 | Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage |
| Q37259446 | Ordered DNA release and target capture in RAG transposition |
| Q35208441 | Organization and dynamics of the Mu transpososome: recombination by communication between two active sites |
| Q33934189 | Playing second fiddle: second-strand processing and liberation of transposable elements from donor DNA. |
| Q34842642 | Presence of a characteristic D-D-E motif in IS1 transposase |
| Q39645547 | Protein-DNA contacts and conformational changes in the Tn10 transpososome during assembly and activation for cleavage |
| Q46734062 | Questions and Assays |
| Q33968434 | Rag-1 mutations associated with B-cell-negative scid dissociate the nicking and transesterification steps of V(D)J recombination |
| Q38348560 | Reorganization of the Mu Transpososome Active Sites during a Cooperative Transition between DNA Cleavage and Joining |
| Q33702230 | Resident aliens: the Tc1/mariner superfamily of transposable elements |
| Q34500837 | Retroviral DNA integration: reaction pathway and critical intermediates |
| Q42642005 | Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination |
| Q64388530 | Single active site catalysis of the successive phosphoryl transfer steps by DNA transposases: insights from phosphorothioate stereoselectivity |
| Q35805063 | Site-specific recombination and partitioning systems in the stable high copy propagation of the 2-micron yeast plasmid |
| Q58708515 | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase |
| Q33966875 | The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination |
| Q73353796 | The RAG1/RAG2 complex constitutes a 3' flap endonuclease: implications for junctional diversity in V(D)J and transpositional recombination |
| Q51104158 | The Tn10 synaptic complex can capture a target DNA only after transposon excision. |
| Q41078625 | The Tn7 transposase is a heteromeric complex in which DNA breakage and joining activities are distributed between different gene products. |
| Q33889071 | The same two monomers within a MuA tetramer provide the DDE domains for the strand cleavage and strand transfer steps of transposition |
| Q27617962 | The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9-A resolution |
| Q34079784 | Tipping the balance between replicative and simple transposition |
| Q64389039 | Tn10 transposition via a DNA hairpin intermediate |
| Q43904704 | Tn5 transposase active site mutants |
| Q35191790 | Trans catalysis in Tn5 transposition |
| Q33888644 | Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro |
| Q33968806 | Two classes of Tn10 transposase mutants that suppress mutations in the Tn10 terminal inverted repeat |
| Q36570713 | piggyBac can bypass DNA synthesis during cut and paste transposition |
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