Two separate functions are encoded by the carboxyl-terminal domains of the yeast cyclase-associated protein and its mammalian homologs. Dimerization and actin binding

scientific article published on 01 July 1996

Two separate functions are encoded by the carboxyl-terminal domains of the yeast cyclase-associated protein and its mammalian homologs. Dimerization and actin binding is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.271.30.18243
P698PubMed publication ID8663401

P2093author name stringX Y Lin
D David
J E Gerst
V Lustgarten
V Protopopov
A Zelicof
P2860cites workIdentification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteinsQ24293740
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymeraseQ26778389
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunitQ27860669
Defining protein interactions with yeast actin in vivoQ27934111
A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localizationQ27935759
Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae.Q27936151
In yeast, RAS proteins are controlling elements of adenylate cyclase.Q27939207
Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated proteinQ27940176
A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vectorQ28131601
Identification of a ten-amino acid proline-rich SH3 binding siteQ28266446
Proline-rich sequences that bind to Src homology 3 domains with individual specificitiesQ28287774
SH3 domains direct cellular localization of signaling moleculesQ30194915
SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.Q31160553
Dynamic actin structures stabilized by profilin.Q35055080
CAP is a bifunctional component of the Saccharomyces cerevisiae adenylyl cyclase complexQ36958354
Genetic and biochemical analysis of the adenylyl cyclase-associated protein, cap, in Schizosaccharomyces pombeQ37370430
Evidence for a functional link between profilin and CAP in the yeast S. cerevisiaeQ38333948
Cytoskeleton-associated cell contactsQ38776715
Amino acid biosynthesis inhibitors as herbicidesQ39532159
Analysis of the function of the 70-kilodalton cyclase-associated protein (CAP) by using mutants of yeast adenylyl cyclase defective in CAP bindingQ43182836
The 70-kilodalton adenylyl cyclase-associated protein is not essential for interaction of Saccharomyces cerevisiae adenylyl cyclase with RAS proteinsQ43183342
SRV2, a gene required for RAS activation of adenylate cyclase in yeastQ43651965
Genetic analysis of mammalian GAP expressed in yeast.Q54722400
ASP-56, a new actin sequestering protein from pig platelets with homology to CAP, an adenylate cyclase-associated protein from yeastQ68069977
An actin monomer binding activity localizes to the carboxyl-terminal half of the Saccharomyces cerevisiae cyclase-associated proteinQ72631492
P433issue30
P407language of work or nameEnglishQ1860
P304page(s)18243-18252
P577publication date1996-07-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleTwo separate functions are encoded by the carboxyl-terminal domains of the yeast cyclase-associated protein and its mammalian homologs. Dimerization and actin binding
P478volume271

Reverse relations

cites work (P2860)
Q34159873A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding
Q47072745A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast
Q37595512A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein.
Q33560040Adenylyl cyclase-associated protein Aca1 regulates virulence and differentiation of Cryptococcus neoformans via the cyclic AMP-protein kinase A cascade
Q48320228Arabidopsis CAP regulates the actin cytoskeleton necessary for plant cell elongation and division
Q35167936CAP1 is overexpressed in human epithelial ovarian cancer and promotes cell proliferation
Q33996222CAP1, an adenylate cyclase-associated protein gene, regulates bud-hypha transitions, filamentous growth, and cyclic AMP levels and is required for virulence of Candida albicans.
Q36138850Capulet and Slingshot share overlapping functions during Drosophila eye morphogenesis
Q27930643Coiled-coil interaction of N-terminal 36 residues of cyclase-associated protein with adenylyl cyclase is sufficient for its function in Saccharomyces cerevisiae ras pathway
Q27939726Conserved alpha-helical segments on yeast homologs of the synaptobrevin/VAMP family of v-SNAREs mediate exocytic function
Q52331924Cyclase-Associated Protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase.
Q35942338Identification of Arabidopsis cyclase-associated protein 1 as the first nucleotide exchange factor for plant actin
Q27933276Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeast
Q38358993Microarray phenotyping places cyclase associated protein CAP at the crossroad of signaling pathways reorganizing the actin cytoskeleton in Dictyostelium
Q42085370Over-expression of Arabidopsis CAP causes decreased cell expansion leading to organ size reduction in transgenic tobacco plants
Q39547547P1 ParB domain structure includes two independent multimerization domains
Q34589289Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin
Q27933088Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover
Q37385566Sec3p is involved in secretion and morphogenesis in Saccharomyces cerevisiae
Q35063771Spaceflight enhances cell aggregation and random budding in Candida albicans.
Q27659030Structure and Function of a G-actin Sequestering Protein with a Vital Role in Malaria Oocyst Development inside the Mosquito Vector
Q45846114The C-terminal dimerization motif of cyclase-associated protein is essential for actin monomer regulation
Q37061517The role of cyclase-associated protein in regulating actin filament dynamics - more than a monomer-sequestration factor.
Q34120315WH2 domain: a small, versatile adapter for actin monomers.
Q27929829Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis
Q27939293Yeast exocytic v-SNAREs confer endocytosis
Q47069951act up controls actin polymerization to alter cell shape and restrict Hedgehog signaling in the Drosophila eye disc
Q39586450t-SNARE phosphorylation regulates endocytosis in yeast

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