Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis

scientific article

Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis is …
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scholarly articleQ13442814

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P356DOI10.1128/MCB.19.6.4480
P3181OpenCitations bibliographic resource ID3454429
P932PMC publication ID104406
P698PubMed publication ID10330187

P2093author name stringJ E Gerst
V Lustgarten
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
n-Sec1: a neural-specific syntaxin-binding proteinQ24561445
Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brainQ24567532
rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxinQ24672828
Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assemblyQ26269962
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunitQ27860669
Coupled ER to Golgi transport reconstituted with purified cytosolic proteinsQ27929807
Targeting of chitin synthase 3 to polarized growth sites in yeast requires Chs5p and Myo2pQ27929862
Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteinsQ27930897
Identification of 23 complementation groups required for post-translational events in the yeast secretory pathwayQ27931724
The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesiclesQ27932839
Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeastQ27933276
Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosisQ27933277
Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiaeQ27933563
Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae.Q27936151
Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C terminus of the SNAP-25 homolog, Sec9.Q27936879
LMA1 binds to vacuoles at Sec18p (NSF), transfers upon ATP hydrolysis to a t-SNARE (Vam3p) complex, and is released during fusionQ27937087
t-SNARE activation through transient interaction with a rab-like guanosine triphosphataseQ27937533
A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritanceQ27937950
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolasesQ27937990
Bos1p, an integral membrane protein of the endoplasmic reticulum to Golgi transport vesicles, is required for their fusion competenceQ27939021
Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamilyQ27939653
Conserved alpha-helical segments on yeast homologs of the synaptobrevin/VAMP family of v-SNAREs mediate exocytic functionQ27939726
A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusionQ27940079
SNAP receptors implicated in vesicle targeting and fusionQ28131653
SNAREpins: minimal machinery for membrane fusionQ28131697
Inhibition of the binding of SNAP-23 to syntaxin 4 by Munc18cQ28239431
Defining the functions of trans-SNARE pairsQ59079276
The C. elegans unc-18 gene encodes a protein expressed in motor neuronsQ70478386
Two separate functions are encoded by the carboxyl-terminal domains of the yeast cyclase-associated protein and its mammalian homologs. Dimerization and actin bindingQ71144124
Yeast Snc proteins complex with Sec9. Functional interactions between putative SNARE proteinsQ72196546
Specificity and regulation of a synaptic vesicle docking complexQ28246613
Protein-protein interactions contributing to the specificity of intracellular vesicular traffickingQ28249692
The effects of vanadate on the plasma membrane ATPase of Neurospora crassaQ28289784
The V0 sector of the V-ATPase, synaptobrevin, and synaptophysin are associated on synaptic vesicles in a Triton X-100-resistant, freeze-thawing sensitive, complexQ28583592
A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cellsQ28594246
Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuolesQ28609819
Vesicle fusion from yeast to manQ29618200
76 β-d-Fructofuranoside fructohydrolase from yeastQ29618502
Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transportQ29619583
The diversity of Rab proteins in vesicle transportQ29620216
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesiclesQ29620271
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxinQ29620437
SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.Q31160553
VAMP-1: a synaptic vesicle-associated integral membrane proteinQ33583102
SNAREs and SNARE regulators in membrane fusion and exocytosisQ33667986
Yeast synaptobrevin homologs are modified posttranslationally by the addition of palmitateQ34173066
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion proteinQ34351277
A rat brain Sec1 homologue related to Rop and UNC18 interacts with syntaxinQ35087004
Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis.Q35917172
The molecular machinery for secretion is conserved from yeast to neuronsQ36184412
Purification and characterization of constitutive secretory vesicles from yeastQ36217910
The role of Myo2, a yeast class V myosin, in vesicular transportQ36235470
COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutantsQ36254565
Biochemical and functional studies of cortical vesicle fusion: the SNARE complex and Ca2+ sensitivityQ36328525
Parallel secretory pathways to the cell surface in yeastQ36382718
Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiaeQ36814551
CAP is a bifunctional component of the Saccharomyces cerevisiae adenylyl cyclase complexQ36958354
A 38,000-dalton membrane protein (p38) present in synaptic vesiclesQ37691886
Saccharomyces cerevisiae mutant defective in exo-1,3-beta-glucanase productionQ39973380
Implications of the SNARE hypothesis for intracellular membrane topology and dynamicsQ40629820
Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.Q40805470
SNAREs and NSF in targeted membrane fusionQ41566661
Vesicle-associated membrane protein-2 (synaptobrevin-2) forms a complex with synaptophysinQ42274081
Cloning and sequencing of the yeast Saccharomyces cerevisiae SEC1 gene localized on chromosome IV.Q43423308
Biosynthesis of acid phosphatase of baker's yeast. Factors influencing its production by protoplasts and characterization of the secreted enzymeQ44680695
Vesicle-associated membrane protein and synaptophysin are associated on the synaptic vesicle.Q46032554
Two vesicle-associated membrane protein genes are differentially expressed in the rat central nervous systemQ46951193
UAS(MAG1), a yeast cis-acting element that regulates the expression of MAG1, is located within the protein coding region of DDI1.Q48046357
The Drosophila Ras2 and Rop gene pair: a dual homology with a yeast Ras-like gene and a suppressor of its loss-of-function phenotype.Q48126918
Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesiclesQ48475060
rop, a Drosophila homolog of yeast Sec1 and vertebrate n-Sec1/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo.Q52541607
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectexocytosisQ323426
Ddi1p YER143WQ27547456
P304page(s)4480-4494
P577publication date1999-06-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleYeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis
P478volume19

Reverse relations

cites work (P2860)
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Q27935070Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways.
Q39855133Phosphorylation of the autoinhibitory domain of the Sso t-SNAREs promotes binding of the Vsm1 SNARE regulator in yeast
Q34672806Predicting the distribution, conservation, and functions of SNAREs and related proteins in fungi
Q35197962SNARE regulators: matchmakers and matchbreakers
Q42571521Sec1p and Mso1p C-terminal tails cooperate with the SNAREs and Sec4p in polarized exocytosis
Q37267119Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Q37774860Surprising roles for phospholipid binding proteins revealed by high throughput genetics
Q42115583The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease
Q27935783The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast
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Q38819431The Sec1/Munc18 Protein Groove Plays a Conserved Role in Interaction with Sec9p/SNAP-25.
Q57301712Transcriptional regulation of the 26S proteasome by Nrf1
Q39644724Two distinct effects on neurotransmission in a temperature-sensitive SNAP-25 mutant.
Q42196272Unique role for the UbL-UbA protein Ddi1 in turnover of SCFUfo1 complexes
Q35169800What is the role of SNARE proteins in membrane fusion?
Q34134524YOS9, the putative yeast homolog of a gene amplified in osteosarcomas, is involved in the endoplasmic reticulum (ER)-Golgi transport of GPI-anchored proteins
Q27939293Yeast exocytic v-SNAREs confer endocytosis
Q79091747p97, a protein coping with multiple identities
Q28346024t-SNARE dephosphorylation promotes SNARE assembly and exocytosis in yeast