What is the role of SNARE proteins in membrane fusion?

scientific article

What is the role of SNARE proteins in membrane fusion? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00091.2003
P698PubMed publication ID12842832
P5875ResearchGate publication ID6663795

P2093author name stringJoseph G Duman
John G Forte
P2860cites workSyntaphilin: a syntaxin-1 clamp that controls SNARE assemblyQ22253305
Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagminQ24291404
Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assemblyQ24302367
Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMPQ24313250
A conformational switch in syntaxin during exocytosis: role of munc18.Q24534308
The membrane-tethering protein p115 interacts with GBF1, an ARF guanine-nucleotide-exchange factorQ24534602
CFTR chloride channels are regulated by a SNAP-23/syntaxin 1A complexQ24535872
A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and functionQ24595623
Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREsQ24656954
Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREsQ27637268
High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complexQ27640208
Structure of influenza haemagglutinin at the pH of membrane fusionQ27730888
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolutionQ27765619
Phosphorylation of Munc18 by protein kinase C regulates the kinetics of exocytosisQ27863317
Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosisQ27929829
Characterization of a novel yeast SNARE protein implicated in Golgi retrograde trafficQ27930083
Influence of lipid composition on physical properties and peg-mediated fusion of curved and uncurved model membrane vesicles: "nature's own" fusogenic lipid bilayer.Q43563695
Syntaxin 3 is required for cAMP-induced acid secretion: streptolysin O-permeabilized gastric gland modelQ43829120
SNARE assembly and disassembly exhibit a pronounced hysteresisQ43851628
Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells.Q44054040
Localization and function of soluble N-ethylmaleimide-sensitive factor attachment protein-25 and vesicle-associated membrane protein-2 in functioning gastric parietal cellsQ44184075
Coiled coils in both intracellular vesicle and viral membrane fusionQ44268531
Functional impact of syntaxin on gating of N-type and Q-type calcium channelsQ44695195
The synaptic SNARE complex is a parallel four-stranded helical bundleQ46079288
Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociationQ46887153
Homotypic vacuolar fusion mediated by t- and v-SNAREsQ48049888
Hrs-2 is an ATPase implicated in calcium-regulated secretionQ48053660
Divalent cation-induced lipid mixing between phosphatidylserine liposomes studied by stopped-flow fluorescence measurements: effects of temperature, comparison of barium and calcium, and perturbation by DPX.Q48304343
Mechanism of calcium-independent synaptotagmin binding to target SNAREsQ48421153
Syntaxin 1A regulates ENaC via domain-specific interactions.Q48836093
The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiencyQ55951827
SynipQ56700520
The riddle of the Sec1/Munc-18 proteins – new twists added to their interactions with SNAREsQ57978966
Inhibition of SNARE Complex Assembly Differentially Affects Kinetic Components of ExocytosisQ57978998
Control of the Terminal Step of Intracellular Membrane Fusion by Protein Phosphatase 1Q58197789
Trans-complex formation by proteolipid channels in the terminal phase of membrane fusionQ59067778
Defining the functions of trans-SNARE pairsQ59079276
Ypt1p implicated in v-SNARE activationQ59095937
Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosomeQ27931703
The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation.Q27932292
Golgi-to-endoplasmic reticulum (ER) retrograde traffic in yeast requires Dsl1p, a component of the ER target site that interacts with a COPI coat subunitQ27932312
Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexesQ27932523
Topological restriction of SNARE-dependent membrane fusionQ27934715
The yeast SLY gene products, suppressors of defects in the essential GTP-binding Ypt1 protein, may act in endoplasmic reticulum-to-Golgi transportQ27935252
Ca2+/calmodulin signals the completion of docking and triggers a late step of vacuole fusion.Q27935567
Compartmental specificity of cellular membrane fusion encoded in SNARE proteinsQ27935841
Vps51p links the VFT complex to the SNARE Tlg1pQ27935910
t-SNARE activation through transient interaction with a rab-like guanosine triphosphataseQ27937533
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuoleQ27937915
Vacuole fusion at a ring of vertex docking sites leaves membrane fragments within the organelleQ27938160
The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12pQ27938749
Sec1p binds to SNARE complexes and concentrates at sites of secretionQ27939711
SNAP receptors implicated in vesicle targeting and fusionQ28131653
SNAREpins: minimal machinery for membrane fusionQ28131697
Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical propertiesQ28144385
SNARE function analyzed in synaptobrevin/VAMP knockout miceQ28203549
Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosisQ28204182
Taxilin; a novel syntaxin-binding protein that is involved in Ca2+-dependent exocytosis in neuroendocrine cellsQ28206148
Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cellsQ28208262
Synaptotagmin: a Ca(2+) sensor that triggers exocytosis?Q28208303
Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosisQ28212791
The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assemblyQ28214428
Spring, a novel RING finger protein that regulates synaptic vesicle exocytosisQ28214515
Snares and Munc18 in synaptic vesicle fusionQ28216761
Action of complexin on SNARE complexQ28219311
A post-docking role for synaptobrevin in synaptic vesicle fusionQ28243803
Protein-protein interactions contributing to the specificity of intracellular vesicular traffickingQ28249692
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusionQ28255534
Protease resistance of syntaxin.SNAP-25.VAMP complexes. Implications for assembly and structureQ28268641
A VAMP-binding protein from Aplysia required for neurotransmitter releaseQ28297054
SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosisQ28364095
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs.Q36546123
The Saccharomyces cerevisiae v-SNARE Vti1p is required for multiple membrane transport pathways to the vacuoleQ36875646
Vesicle-associated membrane protein-2/synaptobrevin binding to synaptotagmin I promotes O-glycosylation of synaptotagmin I.Q38288598
SNARE complex formation is triggered by Ca2+ and drives membrane fusionQ38325384
Mimicry and mechanism in phospholipid models of membrane fusionQ39733207
Fluorescence-based evaluation of the partitioning of lipids and lipidated peptides into liquid-ordered lipid microdomains: a model for molecular partitioning into "lipid rafts".Q40168616
Exocytosis requires asymmetry in the central layer of the SNARE complexQ40388114
Molecular mechanisms of clostridial neurotoxinsQ40642444
Ca2+-dependent interaction of the growth-associated protein GAP-43 with the synaptic core complexQ41099490
Enveloped viruses: a common mode of membrane fusion?.Q41585925
SNARE interactions are not selective. Implications for membrane fusion specificityQ41608272
nSec1 binds a closed conformation of syntaxin1A.Q41716307
Intracellular Ca requirements for stimulus-secretion coupling in parietal cellQ42489820
The neuronal t-SNARE complex is a parallel four-helix bundle.Q43558118
Reconstituted syntaxin1a/SNAP25 interacts with negatively charged lipids as measured by lateral diffusion in planar supported bilayersQ28367662
Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosisQ28509919
Identification of a novel SNAP25 interacting protein (SIP30)Q28580586
Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopyQ28581498
Molecular determinants of regulated exocytosisQ28609688
Membrane fusion and exocytosisQ29614426
Structure and function of membrane fusion peptidesQ30310337
Ocsyn, a novel syntaxin-interacting protein enriched in the subapical region of inner hair cells.Q31091111
Globular tail of myosin-V is bound to vamp/synaptobrevinQ31856369
Complexins regulate a late step in Ca2+-dependent neurotransmitter releaseQ31859100
Membrane fusion: structure snared at lastQ33533780
High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanismQ33880066
Genetic and morphological analyses reveal a critical interaction between the C-termini of two SNARE proteins and a parallel four helical arrangement for the exocytic SNARE complex.Q33889805
"Kiss and run" exocytosis at hippocampal synapsesQ33922918
The ionic layer is required for efficient dissociation of the SNARE complex by alpha-SNAP and NSF.Q33951771
Mechanisms of synaptic vesicle exocytosisQ34059661
Yeast vacuoles and membrane fusion pathwaysQ34086175
VAP-A binds promiscuously to both v- and tSNAREsQ34087281
Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viabilityQ34161948
Structure and composition of the fusion poreQ34180520
Viral fusion peptides: a tool set to disrupt and connect biological membranesQ34293668
Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmissionQ34317092
The molecular mechanism of targeted vesicle transport in cytokinesisQ34593516
Putative fusogenic activity of NSF is restricted to a lipid mixture whose coalescence is also triggered by other factorsQ34667916
Testing the 3Q:1R "rule": mutational analysis of the ionic "zero" layer in the yeast exocytic SNARE complex reveals no requirement for arginineQ34776890
Molecular analysis of SNAP-25 function in exocytosisQ35001438
SNARE proteins contribute to calcium cooperativity of synaptic transmissionQ35582307
The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells.Q36256141
The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis.Q36294041
Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpinsQ36323855
A cycle of Vam7p release from and PtdIns 3-P-dependent rebinding to the yeast vacuole is required for homotypic vacuole fusionQ36324115
Biochemical and functional studies of cortical vesicle fusion: the SNARE complex and Ca2+ sensitivityQ36328525
Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchorsQ36342484
Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domainQ36545881
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)C237-49
P577publication date2003-08-01
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleWhat is the role of SNARE proteins in membrane fusion?
P478volume285

Reverse relations

cites work (P2860)
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