Differential CDK-inhibitor gene expression in aging human diploid fibroblasts

scientific article published on 01 January 1996

Differential CDK-inhibitor gene expression in aging human diploid fibroblasts is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0531-5565(95)00025-9
P698PubMed publication ID8706801

P2093author name stringH Wong
K Riabowol
P2860cites workTHE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINSQ28202269
P433issue1-2
P304page(s)311-325
P577publication date1996-01-01
P1433published inExperimental GerontologyQ15766996
P1476titleDifferential CDK-inhibitor gene expression in aging human diploid fibroblasts
P478volume31

Reverse relations

cites work (P2860)
Q78608295A novel transcriptional inhibitory element differentially regulates the cyclin D1 gene in senescent cells
Q45063615Age dependence of signal transduction and cell signaling as a major factor of intervention into the aging process
Q33930330Biogerontological research in Canada
Q42815554Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
Q24302257CDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanisms
Q37836231Cell cycle arrest is not senescence
Q31096789Cloning and characterization of cellular senescence-associated genes in human fibroblasts by suppression subtractive hybridization
Q39445352Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis
Q36184207Diet and aging
Q38303169Downregulation and forced expression of EWS-Fli1 fusion gene results in changes in the expression of G(1)regulatory genes.
Q36072488Dynamic Bcl-xL (S49) and (S62) Phosphorylation/Dephosphorylation during Mitosis Prevents Chromosome Instability and Aneuploidy in Normal Human Diploid Fibroblasts
Q21245250Epigenetic regulation of caloric restriction in aging
Q38908051Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence
Q35895097From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing.
Q42827551Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres
Q30533934Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells
Q39647398INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence
Q33773096Increased expression of cyclin D2 during multiple states of growth arrest in primary and established cells
Q34166682Increased stability of the p16 mRNA with replicative senescence
Q39444837Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes
Q35185629Involvement of the INK4a/Arf gene locus in senescence
Q35927191Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
Q33969339Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence
Q39126097MEK drives cyclin D1 hyperelevation during geroconversion
Q41702987Molecular aspects of the relationship between cancer and aging: tumor suppressor activity during cellular senescence
Q36460808NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation
Q38573503Progeria, rapamycin and normal aging: recent breakthrough
Q34665706Regulation of senescence in cancer and aging
Q36132413Replicatively senescent cells are arrested in G1 and G2 phases
Q39575910Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression
Q37318496Senescence delay and repression of p16INK4a by Lsh via recruitment of histone deacetylases in human diploid fibroblasts
Q34614217The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway.
Q33889383The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
Q54317457The p16INK4a/CDKN2A tumor suppressor and its relatives.
Q54383317Transcriptional activation of p21(WAF¹/CIP¹) is mediated by increased DNA binding activity and increased interaction between p53 and Sp1 via phosphorylation during replicative senescence of human embryonic fibroblasts.
Q36285300Vitamin E Supplementation Delays Cellular Senescence In Vitro
Q40773189mRNA levels of the differentiation-associated linker histone variant H1 zero in mitotically active and postmitotic senescent human diploid fibroblast cell populations

Search more.