| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1995Sci...270..994H |
| P356 | DOI | 10.1126/SCIENCE.270.5238.994 |
| P698 | PubMed publication ID | 7481806 |
| P50 | author | Olivier Hyrien | Q57079458 |
| P2093 | author name string | M Méchali | |
| C Maric | |||
| P433 | issue | 5238 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 994-997 | |
| P577 | publication date | 1995-11-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Transition in specification of embryonic metazoan DNA replication origins | |
| P478 | volume | 270 |
| Q50421550 | A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis. |
| Q34723884 | A distinct first replication cycle of DNA introduced in mammalian cells |
| Q39446688 | A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage |
| Q34129212 | A new light on DNA replication from the inactive X chromosome |
| Q30438334 | A revisionist replicon model for higher eukaryotic genomes |
| Q35206421 | Activation of dormant origins of DNA replication in budding yeast |
| Q33959297 | Activation of silent replication origins at autonomously replicating sequence elements near the HML locus in budding yeast |
| Q36564912 | Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides |
| Q35642112 | An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene |
| Q36567576 | An origin of replication and a centromere are both needed to establish a replicative plasmid in the yeast Yarrowia lipolytica |
| Q43560219 | Aphidicolin triggers a block to replication origin firing in Xenopus egg extracts |
| Q36796433 | Back to the origin: reconsidering replication, transcription, epigenetics, and cell cycle control |
| Q38245512 | Best practices for mapping replication origins in eukaryotic chromosomes |
| Q42416230 | Broadening of DNA replication origin usage during metazoan cell differentiation |
| Q30430861 | Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription |
| Q43073374 | Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus |
| Q28087148 | Cell cycle control in the early embryonic development of aquatic animal species |
| Q41890131 | Cell cycle modulation of protein-DNA interactions at a human replication origin |
| Q40985225 | Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition. |
| Q41441706 | Chromatin proteins involved in the initiation of DNA replication. |
| Q34290280 | Chromatin remodelling and DNA replication: from nucleosomes to loop domains |
| Q33918547 | Control of DNA replication by cyclin-dependent kinases in development |
| Q93064854 | Control of DNA replication timing in the 3D genome |
| Q34080275 | Control of chromosomal DNA replication in the early Xenopus embryo |
| Q39887690 | CpG methylation of DNA restricts prereplication complex assembly in Xenopus egg extracts. |
| Q39627323 | Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells. |
| Q64087221 | DNA Replication Timing Enters the Single-Cell Era |
| Q36101749 | DNA replication and progression through S phase |
| Q33839410 | DNA replication and transcription programs respond to the same chromatin cues. |
| Q35060936 | DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase |
| Q38496732 | DNA replication origin activation in space and time |
| Q37212976 | DNA replication origins-where do we begin? |
| Q37197487 | DNA replication origins. |
| Q74307721 | DNA replication origins: from sequence specificity to epigenetics |
| Q38781891 | DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation |
| Q42950586 | DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts. |
| Q36553045 | DNA replication: the unbearable lightness of origins |
| Q36160604 | DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins in Drosophila |
| Q37259735 | DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding |
| Q34780596 | Defining the replication program through the chromatin landscape |
| Q34443550 | Developmental changes in the Sciara II/9A initiation zone for DNA replication |
| Q36573274 | Developmental regulation of DNA replication: replication fork barriers and programmed gene amplification in Tetrahymena thermophila |
| Q48039443 | Developmental regulation of MCM replication factors in Xenopus laevis |
| Q34236629 | Developmentally regulated usage of Physarum DNA replication origins |
| Q27694684 | Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns |
| Q35908824 | Differential association of HMG1 and linker histones B4 and H1 with dinucleosomal DNA: structural transitions and transcriptional repression |
| Q37087250 | Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins. |
| Q39747852 | Differential use of multiple replication origins in the ribosomal DNA episome of the protozoan parasite Entamoeba histolytica |
| Q30472999 | Distal sequences, but not ori-beta/OBR-1, are essential for initiation of DNA replication in the Chinese hamster DHFR origin |
| Q33618928 | Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading |
| Q35208336 | Drosophila ORC specifically binds to ACE3, an origin of DNA replication control element |
| Q64268272 | Dynamics of DNA replication in a eukaryotic cell |
| Q51834619 | Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing. |
| Q36290611 | Dynamics of the genome during early Xenopus laevis development: karyomeres as independent units of replication. |
| Q38171275 | Epigenetic landscape for initiation of DNA replication |
| Q36659540 | Eukaryotic DNA replication in a chromatin context |
| Q34139588 | Eukaryotic DNA replication origins: many choices for appropriate answers |
| Q37189674 | Eukaryotic replication origins: Strength in flexibility |
| Q36189305 | Evolutionary diversification of MCM3 genes in Xenopus laevis and Danio rerio |
| Q37245727 | Genome Duplication: The Heartbeat of Developing Organisms |
| Q35195952 | Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features |
| Q35493806 | Genome-wide depletion of replication initiation events in highly transcribed regions |
| Q33257091 | Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae |
| Q37473013 | Genome-wide identification and characterisation of human DNA replication origins by initiation site sequencing (ini-seq). |
| Q35930734 | Genomic specification and epigenetic regulation of eukaryotic DNA replication origins |
| Q30436435 | Genomic study of replication initiation in human chromosomes reveals the influence of transcription regulation and chromatin structure on origin selection |
| Q39808778 | HOXD13 binds DNA replication origins to promote origin licensing and is inhibited by geminin |
| Q39553791 | HUMORAL IMMUNITY. T cell help controls the speed of the cell cycle in germinal center B cells. |
| Q36871689 | Histone H1 reduces the frequency of initiation in Xenopus egg extract by limiting the assembly of prereplication complexes on sperm chromatin |
| Q28214739 | Histone H1 variants differentially inhibit DNA replication through an affinity for chromatin mediated by their carboxyl-terminal domains |
| Q28066336 | How MCM loading and spreading specify eukaryotic DNA replication initiation sites |
| Q40255140 | HoxB domain induction silences DNA replication origins in the locus and specifies a single origin at its boundary. |
| Q24680096 | Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication |
| Q35131778 | Identification of new human origins of DNA replication by an origin-trapping assay. |
| Q33773499 | Identification of primary initiation sites for DNA replication in the hamster dihydrofolate reductase gene initiation zone. |
| Q36846065 | In Xenopus egg extracts, DNA replication initiates preferentially at or near asymmetric AT sequences |
| Q34081692 | In search of the holy replicator |
| Q33665641 | Initiation of DNA replication in eukaryotes: questioning the origin. |
| Q33950632 | Initiation of eukaryotic DNA replication: conservative or liberal? |
| Q48058865 | Interaction between the origin recognition complex and the replication licensing system in Xenopus. |
| Q39723823 | Interaction of transcription factor YY1 with a replication-enhancing element, REE1, in an autonomously replicating human chromosome fragment |
| Q92092095 | Involvement of G-quadruplex regions in mammalian replication origin activity |
| Q44551574 | Isoform switching of Cdc6 contributes to developmental cell cycle remodeling |
| Q42591432 | Low rate of replication fork progression lengthens the replication timing of a locus containing an early firing origin |
| Q24535692 | Making sense of eukaryotic DNA replication origins |
| Q47806318 | Mathematical modelling of eukaryotic DNA replication. |
| Q33862958 | Mechanisms and consequences of replication fork arrest. |
| Q44594153 | Metazoan origin selection: origin recognition complex chromatin binding is regulated by CDC6 recruitment and ATP hydrolysis. |
| Q34819463 | Multiple functional elements comprise a Mammalian chromosomal replicator |
| Q28284492 | Multiple functions of the origin recognition complex |
| Q44399629 | Multiscale analysis of genome-wide replication timing profiles using a wavelet-based signal-processing algorithm. |
| Q41462929 | Non-coding stem-bulge RNAs are required for cell proliferation and embryonic development in C. elegans |
| Q28214779 | Nuclear organization of DNA replication initiation proteins in mammalian cells |
| Q52542122 | Nucleosomes positioned by ORC facilitate the initiation of DNA replication. |
| Q38350701 | ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae |
| Q64251963 | On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway |
| Q36096056 | Open sesame: activating dormant replication origins in the mouse immunoglobulin heavy chain (Igh) locus |
| Q38798065 | Origin plasticity during budding yeast DNA replication in vitro. |
| Q41589627 | POU domain transcription factors in embryonic development |
| Q26829115 | Peaks cloaked in the mist: the landscape of mammalian replication origins |
| Q36376055 | Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA. |
| Q34865206 | Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone |
| Q64899375 | Preserving Genome Integrity During the Early Embryonic DNA Replication Cycles. |
| Q30893892 | RPA is an initiation factor for human chromosomal DNA replication. |
| Q37420353 | Random replication of the inactive X chromosome |
| Q35196112 | Rearrangement of chromatin domains during development in Xenopus |
| Q33959673 | Regulated formation of extrachromosomal circular DNA molecules during development in Xenopus laevis |
| Q37628282 | Regulation of DNA Replication in Early Embryonic Cleavages. |
| Q33751493 | Regulation of eukaryotic DNA replication and nuclear structure |
| Q89171642 | Regulation of the program of DNA replication by CDK: new findings and perspectives |
| Q24679451 | Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells |
| Q36875519 | Replication in context: dynamic regulation of DNA replication patterns in metazoans |
| Q40018801 | Replication initiates at multiple dispersed sites in the ribosomal DNA plasmid of the protozoan parasite Entamoeba histolytica |
| Q34645443 | Replication initiation and elongation fork rates within a differentially expressed human multicopy locus in early S phase |
| Q34440668 | Replication initiation patterns in the beta-globin loci of totipotent and differentiated murine cells: evidence for multiple initiation regions |
| Q36511235 | Replication landscape of the human genome |
| Q35148827 | Replication of the Chicken β-Globin Locus: Early-Firing Origins at the 5′ HS4 Insulator and the ρ- and βA-Globin Genes Show Opposite Epigenetic Modifications |
| Q43744130 | Replication of the rat aldolase B locus differs between aldolase B-expressing and non-expressing cells. |
| Q36370052 | Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times |
| Q41044089 | Replication origins in eukaroytes |
| Q48018615 | Replication origins in yeast versus metazoa: separation of the haves and the have nots |
| Q36169325 | Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality |
| Q41702513 | Role of nuclear architecture in the initiation of eukaryotic DNA replication |
| Q41871129 | Role of replication and CpG methylation in fragile X syndrome CGG deletions in primate cells |
| Q42092579 | Role of the Orc6 protein in origin recognition complex-dependent DNA binding and replication in Drosophila melanogaster |
| Q90282003 | SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development |
| Q24685501 | Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals |
| Q36846885 | Short DNA fragments without sequence similarity are initiation sites for replication in the chromosome of the yeast Yarrowia lipolytica |
| Q34012854 | Site-specific DNA binding of the Schizosaccharomyces pombe origin recognition complex is determined by the Orc4 subunit |
| Q39607892 | Site-specific and temporally controlled initiation of DNA replication in a human cell-free system |
| Q47251784 | Sleeping policemen for DNA replication? |
| Q24812145 | Spatial distribution and specification of mammalian replication origins during G1 phase |
| Q30436775 | Specific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replication |
| Q54710492 | Specification of a DNA replication origin by a transcription complex. |
| Q33957180 | Specification of regions of DNA replication initiation during embryogenesis in the 65-kilobase DNApolalpha-dE2F locus of Drosophila melanogaster |
| Q35152182 | The 'ORC cycle': a novel pathway for regulating eukaryotic DNA replication |
| Q24676925 | The Croonian Lecture 2001 hunting the antisocial cancer cell: MCM proteins and their exploitation |
| Q30310418 | The dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity |
| Q35213256 | The dynamics of chromosome replication in yeast |
| Q30430707 | The effect of the intra-S-phase checkpoint on origins of replication in human cells |
| Q51033425 | The gastrula transition reorganizes replication-origin selection in Caenorhabditis elegans. |
| Q36242767 | The histone acetyltransferases CBP and Chameau integrate developmental and DNA replication programs in Drosophila ovarian follicle cells |
| Q24794185 | The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells |
| Q37276589 | The human beta-globin replication initiation region consists of two modular independent replicators |
| Q35210893 | The hunt for origins of DNA replication in multicellular eukaryotes |
| Q35192617 | The midblastula transition defines the onset of Y RNA-dependent DNA replication in Xenopus laevis |
| Q30312133 | The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries |
| Q36569595 | The replication origin decision point is a mitogen-independent, 2-aminopurine-sensitive, G1-phase event that precedes restriction point control |
| Q34573833 | The ribosomal DNA plasmids of entamoeba |
| Q30566253 | Titration of four replication factors is essential for the Xenopus laevis midblastula transition |
| Q91972654 | Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide |
| Q38095707 | Transcription-replication encounters, consequences and genomic instability |
| Q33888532 | Transformation abrogates an early G1-phase arrest point required for specification of the Chinese hamster DHFR replication origin |
| Q50453069 | Unearthing worm replication origins. |
| Q73009397 | Unpaired structures in SCA10 (ATTCT)n.(AGAAT)n repeats |
| Q39321886 | Unraveling cell type-specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs. |
| Q39092227 | Xenopus egg extract to study regulation of genome-wide and locus-specific DNA replication. |
| Q35160505 | Xenopus origin recognition complex (ORC) initiates DNA replication preferentially at sequences targeted by Schizosaccharomyces pombe ORC. |
| Q48966862 | Xenopus replication assays. |
| Q77940195 | [Is the replicon model applicable to higher eukaryotes?] |
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