Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA.

scientific article

Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.MOLCEL.2015.10.022
P932PMC publication ID4680849
P698PubMed publication ID26656162

P50authorJulien GrosQ56462573
Dirk RemusQ57018964
Iestyn WhitehouseQ57339074
Tejas YadavQ57514795
P2093author name stringGerard Lynch
Charanya Kumar
P2860cites workModel-based analysis of ChIP-Seq (MACS)Q21183902
Conserved nucleosome positioning defines replication originsQ24595251
Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication originsQ24600305
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replicationQ24647097
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensingQ24647856
Efficient termination of transcription by RNA polymerase I requires the 5' exonuclease Rat1 in yeastQ24657729
An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexesQ24676407
Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2Q24683693
The requirement of yeast replication origins for pre-replication complex proteins is modulated by transcriptionQ24793913
Mechanisms for initiating cellular DNA replicationQ26827264
Peaks cloaked in the mist: the landscape of mammalian replication originsQ26829115
Disengaging polymerase: terminating RNA polymerase II transcription in budding yeastQ26851212
Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phaseQ27930849
An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeastQ27931174
Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional terminationQ27933929
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.Q27934493
Bidirectional promoters generate pervasive transcription in yeastQ29614766
Two steps in the assembly of complexes at yeast replication origins in vivoQ29618323
The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundariesQ30312133
Specific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replicationQ30436775
Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cellsQ30446544
Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionQ30593837
Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiaeQ33257091
Specification of regions of DNA replication initiation during embryogenesis in the 65-kilobase DNApolalpha-dE2F locus of Drosophila melanogasterQ33957180
In search of the holy replicatorQ34081692
Separation of DNA replication from the assembly of break-competent meiotic chromosomesQ34277075
The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo modelQ34511126
DNA replication timingQ34654036
Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loadingQ34714083
Transcription through the yeast origin of replication ARS1 ends at the ABFI binding site and affects extrachromosomal maintenance of minichromosomesQ34877520
Initiation of DNA replication from non-canonical sites on an origin-depleted chromosomeQ35500170
A genomic view of eukaryotic DNA replication.Q36114739
Quantitative, genome-wide analysis of eukaryotic replication initiation and terminationQ36771862
Transcription interferes with elements important for chromosome maintenance in Saccharomyces cerevisiaeQ36789051
Extensive transcriptional heterogeneity revealed by isoform profilingQ36993727
DNA replication as a target of the DNA damage checkpointQ37511322
How dormant origins promote complete genome replicationQ37884997
Preventing replication stress to maintain genome stability: resolving conflicts between replication and transcriptionQ37998652
Regulating DNA replication in eukaryaQ38120365
Causes of genome instabilityQ38126068
Dealing with pervasive transcription.Q38165377
Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins.Q38293922
Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replicationQ38798047
Origin plasticity during budding yeast DNA replication in vitro.Q38798065
Single-molecule imaging of FtsK translocation reveals mechanistic features of protein-protein collisions on DNA.Q40412605
Replication initiates at multiple locations on an autonomously replicating plasmid in human cellsQ40677658
Isolation and characterisation of a yeast chromosomal replicatorQ41121934
Relicensing of transcriptionally inactivated replication origins in budding yeastQ41130510
Intrinsic coupling of lagging-strand synthesis to chromatin assembly.Q41457868
Cohesin relocation from sites of chromosomal loading to places of convergent transcriptionQ41809530
Linear derivatives of Saccharomyces cerevisiae chromosome III can be maintained in the absence of autonomously replicating sequence elementsQ42412817
Reversion of autonomously replicating sequence mutations in Saccharomyces cerevisiae: creation of a eucaryotic replication origin within procaryotic vector DNA.Q43183612
The units of DNA replication in Drosophila melanogaster chromosomes.Q52471119
Termination by torpedoQ56602188
Prereplication-complex formation: a molecular double take?Q57756157
Transition in specification of embryonic metazoan DNA replication originsQ71542161
Regulated replication of DNA microinjected into eggs of Xenopus laevisQ72871670
Perturbation of the activity of replication origin by meiosis-specific transcriptionQ79434292
P433issue5
P304page(s)797-807
P577publication date2015-11-19
P1433published inMolecular CellQ3319468
P1476titlePost-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA.
P478volume60

Reverse relations

cites work (P2860)
Q58553479A journey with common fragile sites: from S-phase to telophase
Q64255297Bayesian inference of origin firing time distributions, origin interference and licencing probabilities from Next Generation Sequencing data
Q51434143Both DNA Polymerases δ and ε Contact Active and Stalled Replication Forks Differently.
Q51003935Chromatin Constrains the Initiation and Elongation of DNA Replication.
Q60935156Common Chromosomal Fragile Sites-Conserved Failure Stories
Q39027290Conflict Resolution in the Genome: How Transcription and Replication Make It Work
Q64250001Control of Eukaryotic DNA Replication Initiation-Mechanisms to Ensure Smooth Transitions
Q46428907Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.
Q37212976DNA replication origins-where do we begin?
Q39392236Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development
Q64889763Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse.
Q64268272Dynamics of DNA replication in a eukaryotic cell
Q37189674Eukaryotic replication origins: Strength in flexibility
Q100558661Evolution of DNA replication origin specification and gene silencing mechanisms
Q47574262FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells
Q39440326From structure to mechanism-understanding initiation of DNA replication.
Q28066336How MCM loading and spreading specify eukaryotic DNA replication initiation sites
Q38833501How and why multiple MCMs are loaded at origins of DNA replication
Q89830480Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes
Q61446988Mechanism of Bidirectional Leading-Strand Synthesis Establishment at Eukaryotic DNA Replication Origins
Q91362804Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM
Q39017132Mechanisms and regulation of DNA replication initiation in eukaryotes
Q47172875Noise in the Machine: Alternative Pathway Sampling is the Rule During DNA Replication
Q58606936Noncoding transcription influences the replication initiation program through chromatin regulation
Q42290808Nucleosomes influence multiple steps during replication initiation
Q37199965ORChestrating the human DNA replication program
Q86320168Origins of DNA replication
Q60950826Pervasive transcription fine-tunes replication origin activity
Q64103307Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes
Q58694617Recent advances in understanding DNA replication: cell type-specific adaptation of the DNA replication program
Q28068574Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability
Q36969038Replicating Large Genomes: Divide and Conquer
Q34550677Rescue from replication stress during mitosis
Q91982957Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats
Q64086139The Emerging Roles of TERRA in Telomere Maintenance and Genome Stability
Q52390983The Temporal Regulation of S Phase Proteins During G1.
Q55505048The eukaryotic bell-shaped temporal rate of DNA replication origin firing emanates from a balance between origin activation and passivation.
Q39438600The impact of replication stress on replication dynamics and DNA damage in vertebrate cells.
Q90833332Transcription shapes DNA replication initiation and termination in human cells
Q90833348Transcription-dependent regulation of replication dynamics modulates genome stability
Q91972654Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
Q92254240Transcription-mediated replication hindrance: a major driver of genome instability
Q38994629Transcription-replication conflicts at chromosomal fragile sites-consequences in M phase and beyond
Q52712164[How genomic approaches help the understanding of the initiation of DNA replication].

Search more.