Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety

scientific article published on 01 October 1995

Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1378/CHEST.108.4_SUPPLEMENT.258S
P698PubMed publication ID7555181

P2093author name stringJ Hirsh
T E Warkentin
L Poller
D Deykin
R Raschke
J E Dalen
P433issue4 Suppl
P407language of work or nameEnglishQ1860
P921main subjectheparinQ190016
pharmacokineticsQ323936
P304page(s)258S-275S
P577publication date1995-10-01
P1433published inChestQ5093377
P1476titleHeparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety
P478volume108

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cites work (P2860)
Q47280059A model for collaboration in quality improvement projects: implementing a weight-based heparin dosing nomogram across an integrated health care delivery system
Q31939613A randomized, multicenter trial of weight-adjusted intravenous heparin dose titration and point-of-care coagulation monitoring in hospitalized patients with active thromboembolic disease. Antithrombotic Therapy Consortium Investigators.
Q27339266A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
Q71724580ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction)
Q74600262Activated clotting time as a screening test prior to catheter-based cardiovascular procedures
Q38524632Anti-Inflammatory Effects of Heparin and Its Derivatives: A Systematic Review
Q37368145Anticoagulant synergism of heparin and activated protein C in vitro. Role of a novel anticoagulant mechanism of heparin, enhancement of inactivation of factor V by activated protein C
Q33671937Anticoagulant therapy in unstable angina.
Q43990299Anticoagulation therapy in children.
Q34751947Anticoagulation therapy in patients with venous thromboembolic disease
Q37013823Antitcoagulant and antiplatelet activities of scolymoside
Q33740235Antithrombin agents as adjuncts to thrombolytic therapy
Q36611360Antithrombotic and antiplatelet activities of small-molecule alkaloids from Scolopendra subspinipes mutilans.
Q77747914Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat
Q44632467Antithrombotic properties of JJ1, a potent and novel thrombin inhibitor
Q87036708Approach to acute ischemic stroke in childhood
Q78058370Argatroban
Q73832105Bivalirudin compared with heparin during coronary angioplasty for thrombus-containing lesions
Q30479354Blood flow velocity effects and role of activation delay time on growth and form of platelet thrombi
Q40899580Brain attack. Acute therapeutic intervention. Antithrombotic and antiplatelet-aggregating drugs.
Q37231751Citrate pharmacokinetics and calcium levels during high-flux dialysis with regional citrate anticoagulation
Q73511216Clinical and analytic diagnostic evaluation of deep venous thrombosis of the lower limbs
Q73299942Clinical and economic effectiveness of an inpatient anticoagulation service
Q35566175Clinician update: direct thrombin inhibitors in acute coronary syndromes
Q44635344Comparison of effectiveness and safety of three different antithrombotic regimens (bivalirudin, eptifibatide, and heparin) in preventing myocardial ischemia during percutaneous coronary intervention
Q52206720Correlation of activated clotting time and activated partial thromboplastin time to plasma heparin concentration.
Q44777970Cost-minimization analysis of low-molecular-weight heparin (dalteparin) compared to unfractionated heparin for inpatient treatment of cancer patients with deep venous thrombosis
Q35159120Current anticoagulant therapy--unmet clinical needs
Q40883424Current concepts of anticoagulant therapy in pregnancy
Q35141098Current trends in preoperative patient evaluation and management for podiatric surgeons
Q34144439Deep vein thrombosis: a clinical review
Q51801551Deep venous thrombosis prophylaxis in trauma: improved compliance with a novel miniaturized pneumatic compression device.
Q73587258Design of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)
Q34027292Direct thrombin inhibitors as adjuncts to thrombolytic therapy
Q90749273Direct-Acting Oral Anticoagulants and Their Reversal Agents-An Update
Q33332127Drug-Induced Thrombocytopenia: Is it a Serious Concern for Glycoprotein IIb/IIIa Receptor Inhibitors?
Q34571023Drugs, their targets and the nature and number of drug targets
Q34007527Emerging concepts in the diagnosis and management of venous thromboembolism during pregnancy
Q38124690Evaluation of initial heparin infusion rates for a high-dose protocol
Q42057735Factor V Leiden and Cardiopulmonary Bypass
Q41945608Hemocompatibility of silicon-based substrates for biomedical implant applications
Q73635489Hemostasis Laboratory: Assays for Platelet Function and Von Willebrand Disease
Q64059120Heparin Differentially Impacts Gene Expression of Stromal Cells from Various Tissues
Q33328818Heparin and low-molecular-weight heparin in the treatment of venous thromboembolism
Q33346855Heparin-induced thrombocytopenia, paradoxical thromboembolism, and other adverse effects of heparin-type therapy
Q33502912Heparin-induced thrombocytopenia, paradoxical thromboembolism, and other side effects of heparin therapy
Q38926114How We Manage Pediatric Deep Venous Thrombosis
Q40344129Improvement in long-term ECMO by detailed monitoring of anticoagulation: a case report
Q30710756In vitro and in vivo characterization of a reversible synthetic heparin analog
Q35043999Low molecular weight heparin-induced skin necrosis: a case report
Q33340903Low molecular weight heparins: a guide to their optimum use in pregnancy
Q47316212Low-Molecular-Weight Heparin in the Initial Treatment of Proximal Deep Vein Thrombosis
Q47278479Low-molecular-weight heparin for the treatment of venous thrombosis in patients with adenocarcinoma
Q77919968Low-molecular-weight heparins
Q41707230Low-molecular-weight heparins for acute coronary syndromes
Q41635572Manipulation of coagulation factors in acute stroke
Q33781946New-generation anticoagulants: the low molecular weight heparins
Q41238308Optical sensing of anticoagulation status: Towards point-of-care coagulation testing
Q33892529Outpatient Therapy of Deep Vein Thrombosis
Q41738328Pathophysiologic bases for adjunctive therapies in the treatment and secondary prevention of acute myocardial infarction.
Q34448244Pharmacologic preservation of the hemostatic system during cardiac surgery
Q24336588Phosphatidylserine-positive erythrocytes bind to immobilized and soluble thrombospondin-1 via its heparin-binding domain
Q74244637Platelet inhibitors and bleeding in cardiac surgical patients
Q74244632Platelet inhibitors and cardiac surgery
Q92570086Polyelectrolyte Complexes between Polycarboxylates and BMP-2 for Enhancing Osteogenic Differentiation: Effect of Chemical Structure of Polycarboxylates
Q73236504Prevention and management of venous thromboembolism in pregnancy
Q33496843Prevention and treatment of venous thromboembolism
Q77900564Problems with monitoring heparin anticoagulation
Q34190401Regional anesthesia and anticoagulation
Q44169606Regional anticoagulation with acid citrate dextrose-A for extracorporeal photoimmunochemotherapy.
Q77742224Risk reduction in the intensive care unit
Q58776756Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway
Q33405311Systemic infusion and local irrigation with argatroban effective in preventing clot formation during carotid endarterectomy in a patient with heparin-induced thrombocytopenia
Q27349460The Extrinsic Coagulation Pathway: a Biomarker for Suicidal Behavior in Major Depressive Disorder
Q33685763The influence of developmental haemostasis on the laboratory diagnosis and management of haemostatic disorders during infancy and childhood.
Q37794277The investigation of a prolonged APTT with specific clotting factor assays is unnecessary if an APTT with Actin FS is normal
Q73681259Thrombin Generation in Patients with Acute Myocardial Infarction Treated with Front-Loaded rt-PA and Recombinant Hirudin (HBW 023)
Q73081804Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary syndromes: potential mechanisms for heightened prothrombotic potential
Q88586250Tissue Engineering at the Blood-Contacting Surface: A Review of Challenges and Strategies in Vascular Graft Development
Q40853404Treatment of deep venous thrombosis and pulmonary embolism. Current recommendations
Q36795731Treatment of high-risk venous thrombosis patients using low-dose intraclot injections of recombinant tissue plasminogen activator and regional anticoagulation
Q34474126Treatment options for deep venous thrombosis
Q40853392Unfractionated and low-molecular-weight heparin. Comparisons and current recommendations
Q33333960Use of direct thrombin inhibitors in acute coronary syndrome
Q28212381Use of unfractionated heparin and a low-molecular-weight heparin following thrombolytic therapy for acute ST-segment elevation myocardial infarction
Q38807947Veno-venous extracorporeal membrane oxygenation support during lung volume reduction surgery for a severe respiratory failure patient with emphysema
Q77919973Venous thromboembolic events in pediatric patients. Diagnosis and management
Q47281474Weight-based heparin dosing: clinical response and resource utilization
Q77478352[Epidural lumbar hematoma, epidural anesthesia and low-molecular-weight heparins]

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