Thrombin Generation in Patients with Acute Myocardial Infarction Treated with Front-Loaded rt-PA and Recombinant Hirudin (HBW 023)

scientific article published on 01 July 1998

Thrombin Generation in Patients with Acute Myocardial Infarction Treated with Front-Loaded rt-PA and Recombinant Hirudin (HBW 023) is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1009005267
P356DOI10.1023/A:1008839824942
P698PubMed publication ID10767116

P2093author name stringNeuhaus KL
Zeymer U
Mateblowski M
P2860cites workComparison of hirudin and heparin as adjuncts to streptokinase thrombolysis in a canine model of coronary thrombosisQ70669330
Hirudin in acute myocardial infarction. Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9B trialQ71493537
Recombinant hirudin as a periprocedural antithrombotic in coronary angioplasty for unstable angina pectorisQ71683207
Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safetyQ71732646
Distinct effects of recombinant desulfatohirudin (Revasc) and heparin on plasma levels of fibrinopeptide A and prothrombin fragment F1.2 in unstable angina. A multicenter trialQ71785107
Recombinant hirudin (HBW 023) produces stable anticoagulation unaffected by circadian variation in patients with thrombolysis for acute myocardial infarctionQ71875422
Thrombin generation during infusion of tissue-type plasminogen activatorQ72215676
A pilot trial of recombinant desulfatohirudin compared with heparin in conjunction with tissue-type plasminogen activator and aspirin for acute myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI) 5 trialQ72332452
Thrombin generation and activity during thrombolysis and concomitant heparin therapy in patients with acute myocardial infarctionQ72352876
Failure of fixed dose intravenous heparin to suppress increases in thrombin activity after coronary thrombolysis with streptokinaseQ72726606
Persistent thrombin generation in humans during specific thrombin inhibition with hirudinQ72893501
Hirudin: Its Biology and Clinical UseQ73286001
Determination of r DNA hirudin and A-human thrombin- hirudin complex in plasma samples: enzyme linked immunosorbent assays for hirudin and complex vs. chromogenic thrombin substrate assayQ33191811
Increased thrombin levels during thrombolytic therapy in acute myocardial infarction. Relevance for the success of therapyQ33383834
Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injuryQ34576143
The pathogenesis of coronary artery disease and the acute coronary syndromes (1).Q36728740
Development of hirudin as an antithrombotic agentQ38735170
Coronary Plaque DisruptionQ40459835
Plasma fibrinopeptide A levels in patients with acute myocardial infarction treated with alteplase. Correlation with concomitant heparin, coronary artery patency, and recurrent ischemia. The European Cooperative Study GroupQ41112658
Effect of thrombin inhibition on the dynamics of thrombolysis and on platelet function during thrombolytic therapyQ44519440
A Comparison of Recombinant Hirudin with Heparin for the Treatment of Acute Coronary SyndromesQ56945341
Usefulness of fibrinogenolytic and procoagulant markers during thrombolytic therapy in predicting clinical outcomes in acute myocardial infarctionQ57798992
Increased thrombin activity during thrombolysisQ67963629
Relative efficacy of antithrombin compared with antiplatelet agents in accelerating coronary thrombolysis and preventing early reocclusionQ67984272
Determination of human thrombin-antithrombin III complex in plasma with an enzyme-linked immunosorbent assayQ68337253
Paradoxic elevation of fibrinopeptide A after streptokinase: evidence for continued thrombosis despite intense fibrinolysisQ69224498
P433issue3
P921main subjecthirudinQ386715
acute myocardial infarctionQ18558122
P304page(s)203-207
P577publication date1998-07-01
P1433published inJournal of Thrombosis and ThrombolysisQ15766541
P1476titleThrombin Generation in Patients with Acute Myocardial Infarction Treated with Front-Loaded rt-PA and Recombinant Hirudin (HBW 023)
P478volume5