Blunted cGMP response to agonists and enhanced glomerular cyclic 3',5'-nucleotide phosphodiesterase activities in experimental congestive heart failure

scientific article published on 01 November 1996

Blunted cGMP response to agonists and enhanced glomerular cyclic 3',5'-nucleotide phosphodiesterase activities in experimental congestive heart failure is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/KI.1996.491
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/ki.1996.491
P698PubMed publication ID8914042

P2093author name stringA Luchner
J C Burnett
T P Dousa
T Supaporn
D M Heublein
S M Sandberg
C M Wei
D D Borgeson
P2860cites workA rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Natriuretic peptide system in human heart failureQ28261612
Concentrating defect in the adrenalectomized rat. Abnormal vasopressin-sensitive cyclic adenosine monophosphate metabolism in the papillary collecting ductQ33822324
Role of endogenous atrial natriuretic factor in acute congestive heart failureQ34581546
A functional role for endogenous atrial natriuretic peptide in a canine model of early left ventricular dysfunctionQ35552979
Cellular action of vasopressin in medullary tubules of mice with hereditary nephrogenic diabetes insipidusQ37023926
Modulation of cyclic nucleotides in islated rat glomeruli: role of histamine, carbamylcholine, parathyroid hormone, and angiotensin-II.Q37034302
Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP.Q37690399
The biochemical pharmacology of atrial peptidesQ38253632
Action of serotonin (5-hydroxytryptamine) on cyclic nucleotides in glomeruli of rat renal cortexQ40254672
Atrial natriuretic factor in normal subjects and heart failure patients. Plasma levels and renal, hormonal, and hemodynamic responses to peptide infusionQ40919655
ADH resistance of LLC-pk1 cells caused by overexpression of cAMP-phosphodiesterase type-IV.Q41549700
Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMPQ41555372
Isozymes of cyclic-3',5'-nucleotide phosphodiesterases in renal epithelial LLC-PK1 cellsQ41650216
High activity of low-Michaelis-Menten constant 3', 5'-cyclic adenosine monophosphate-phosphodiesterase isozymes in renal inner medulla of mice with hereditary nephrogenic diabetes insipidusQ44578831
Different effects of ANP and nitroprusside on cyclic GMP extrusion of isolated aortaQ45177577
Pathophysiological role of changing atrial size and pressure in modulation of atrial natriuretic factor during evolving experimental heart failureQ47445197
Second messenger changes of atrial natriuretic factor and brain natriuretic peptide in kidneys of cardiomyopathic hamstersQ48221167
Natriuretic peptides as cardiac hormones in normotensive and spontaneously hypertensive rats. The ventricle is a major site of synthesis and secretion of brain natriuretic peptideQ48682176
Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure.Q53790656
Decreased atrial natriuretic factor receptors and impaired cGMP generation in glomeruli from the cardiomyopathic hamster.Q54357501
Renal and adrenal resistance against atrial natriuretic peptide in congestive heart failure: effect of angiotensin I-converting-enzyme inhibition.Q54367434
Dual mechanism of angiotensin II inhibits ANP-induced mesangial cGMP accumulationQ67703444
Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD)Q68430599
Application of a radioimmunoassay for angiotensin I to the physiologic measurements of plasma renin activity in normal human subjectsQ68602093
Assay of cyclic nucleotide phosphodiesterase using radiolabeled and fluorescent substratesQ69836010
Atrial natriuretic peptide elevation in congestive heart failure in the humanQ69987259
Rapid ventricular pacing in the dog: pathophysiologic studies of heart failureQ70014821
Stimulation of cyclic GMP synthesis in human cultured glomerular cells by atrial natriuretic peptideQ70144109
The renin-angiotensin-aldosterone system, antidiuretic hormone and sympathetic nerve activity in an experimental model of congestive heart failure in the dogQ70334836
Cardiorenal and neurohumoral function in a canine model of early left ventricular dysfunctionQ70743359
Endothelin in human congestive heart failureQ72344120
Increased nitric oxide production in heart failureQ72687252
Formation of reactive oxygen metabolites in glomeruli is suppressed by inhibition of cAMP phosphodiesterase isozyme type IVQ72735569
Presence of C-type natriuretic peptide in human kidney and urineQ72898091
Inhibition of cyclic GMP phosphodiesterases augments renal responses to atrial natriuretic factor in congestive heart failureQ74011048
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectheart failureQ181754
congestive heart failureQ19000661
P304page(s)1718-1725
P577publication date1996-11-01
P1433published inKidney InternationalQ6404823
P1476titleBlunted cGMP response to agonists and enhanced glomerular cyclic 3',5'-nucleotide phosphodiesterase activities in experimental congestive heart failure
P478volume50

Reverse relations

cites work (P2860)
Q74315515Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure
Q26745608Altered Nitric Oxide System in Cardiovascular and Renal Diseases
Q37108057Amino-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide in the general community: determinants and detection of left ventricular dysfunction
Q37257355B-type natriuretic peptide: beyond a diagnostic
Q37256856Biodesign of a renal-protective peptide based on alternative splicing of B-type natriuretic peptide
Q33573360Brain natriuretic peptide in pulmonary arterial hypertension: biomarker and potential therapeutic agent
Q36860608Cenderitide: structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions
Q43777080Effects of therapeutic doses of human atrial natriuretic peptide on load and myocardial performance in patients with congestive heart failure
Q28564609Endogenous or overexpressed cGMP-dependent protein kinases inhibit cAMP-dependent renin release from rat isolated perfused kidney, microdissected glomeruli, and isolated juxtaglomerular cells
Q37209666Endothelial permeability in vitro and in vivo: protective actions of ANP and omapatrilat in experimental atherosclerosis
Q39258545Evolving treatment strategies for management of cardiorenal syndrome
Q33792340Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte
Q28567704Increased activity of cGMP-specific phosphodiesterase (PDE5) contributes to resistance to atrial natriuretic peptide natriuresis in the pregnant rat
Q61576278Increased activity of guanosine 3′-5′-cyclic monophosphate phosphodiesterase in the renal tissue of cirrhotic rats with ascites
Q42077578Increased peripheral resistance in heart failure: new evidence suggests an alteration in vascular smooth muscle function
Q37395026Increased renal phosphodiesterase-5 activity mediates the blunted natriuretic response to ANP in the pregnant rat.
Q37108093Maximizing the renal cyclic 3'-5'-guanosine monophosphate system with type V phosphodiesterase inhibition and exogenous natriuretic peptide: a novel strategy to improve renal function in experimental overt heart failure
Q37329891Modulation of cGMP in heart failure: a new therapeutic paradigm
Q34027488Natriuretic peptides in the pathophysiology of congestive heart failure
Q38594785New medical therapies for heart failure
Q34622165Peripheral limitations of maximal aerobic capacity in patients with chronic heart failure
Q92009329Rosiglitazone treatment restores renal responsiveness to atrial natriuretic peptide in rats with congestive heart failure
Q37091016The cyclic guanosine monophosphate/B-type natriuretic peptide ratio and mortality in advanced heart failure
Q38973055The enigma of continual plasma volume expansion in pregnancy: critical role of the renin-angiotensin-aldosterone system

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