Modulation of cGMP in heart failure: a new therapeutic paradigm

scientific article published on January 2009

Modulation of cGMP in heart failure: a new therapeutic paradigm is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/978-3-540-68964-5_21
P932PMC publication ID3835600
P698PubMed publication ID19089342

P50authorHarald LappQ87662882
P2093author name stringJohn C Burnett
Guido Boerrigter
P2860cites workHeart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics SubcommitteeQ22306347
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Natriuretic peptides and nitric oxide stimulate cGMP synthesis in different cellular compartments.Q36295757
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Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinasesQ44248152
Cardiorenal and humoral properties of a novel direct soluble guanylate cyclase stimulator BAY 41-2272 in experimental congestive heart failureQ44310085
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Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclaseQ44626758
Brain natriuretic peptide enhances renal actions of furosemide and suppresses furosemide-induced aldosterone activation in experimental heart failureQ44801369
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Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in miceQ44935527
Nesiritide does not improve renal function in patients with chronic heart failure and worsening serum creatinineQ45037057
Effects of the sGC stimulator BAY 41-2272 are not mediated by phosphodiesterase 5 inhibitionQ45069627
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophyQ45235067
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Oral human brain natriuretic peptide activates cyclic guanosine 3',5'-monophosphate and decreases mean arterial pressureQ46630199
Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro formQ46778176
Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclaseQ46839590
Long-term use of sildenafil in the therapeutic management of heart failureQ46883859
Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trialsQ46928598
Bioactivity and metabolism of C-type natriuretic peptide in normal manQ48108551
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Clinical trials update from the American College of Cardiology 2007: ALPHA, EVEREST, FUSION II, VALIDD, PARR-2, REMODEL, SPICE, COURAGE, COACH, REMADHE, pro-BNP for the evaluation of dyspnoea and THIS-dietQ48178091
Targeting heme-oxidized soluble guanylate cyclase in experimental heart failureQ48260348
Effects of perioperative nesiritide in patients with left ventricular dysfunction undergoing cardiac surgery:the NAPA TrialQ48276995
Different effects of atrial and C-type natriuretic peptide on the urinary excretion of endothelin-1 in man.Q48365608
Des-serine-proline brain natriuretic peptide 3-32 in cardiorenal regulation.Q48386405
BNP-induced activation of cGMP in human cardiac fibroblasts: interactions with fibronectin and natriuretic peptide receptors.Q48417679
Low dose nesiritide and the preservation of renal function in patients with renal dysfunction undergoing cardiopulmonary-bypass surgery: a double-blind placebo-controlled pilot study.Q48564630
Hemodynamic, renal, and hormonal responses to brain natriuretic peptide infusion in patients with congestive heart failure.Q48643573
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.Q48649829
Successive action of meprin A and neprilysin catabolizes B-type natriuretic peptide.Q52923660
Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension.Q53178301
Lack of efficacy of neutral endopeptidase inhibitor ecadotril in heart failure. The International Ecadotril Multi-centre Dose-ranging Study Investigators.Q53353952
Effects of intravenous atrial natriuretic peptide on cardiac sympathetic nerve activity and left ventricular remodeling in patients with first anterior acute myocardial infarction.Q53499842
Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.Q53560448
Subcutaneous administration of brain natriuretic peptide in experimental heart failure.Q54029914
Cardiovascular and renal actions of C-type natriuretic peptideQ54277308
Placebo-controlled comparison of candoxatril, an orally active neutral endopeptidase inhibitor, and captopril in patients with chronic heart failureQ57396392
Haemodynamic and clinical effects of ularitide in decompensated heart failureQ66829320
Action of C-type natriuretic peptide in isolated canine arteries and veinsQ70555577
Blunted cGMP response to agonists and enhanced glomerular cyclic 3',5'-nucleotide phosphodiesterase activities in experimental congestive heart failureQ71769824
C-type natriuretic peptide: a selective cardiovascular peptideQ72955879
Effects of natriuretic peptides on load and myocardial function in normal and heart failure dogsQ73377155
Therapy with nitroglycerin increases coronary vasoconstriction in response to acetylcholineQ77700106
Renal hyporesponsiveness to atrial natriuretic peptide in congestive heart failure results from reduced atrial natriuretic peptide receptor concentrationsQ79691736
Targeting heme-oxidized soluble guanylate cyclase: solution for all cardiorenal problems in heart failure?Q79837496
Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: evidence of a free-radical-mediated mechanismQ80063618
Differential regulation of membrane guanylyl cyclases in congestive heart failure: natriuretic peptide receptor (NPR)-B, Not NPR-A, is the predominant natriuretic peptide receptor in the failing heartQ80107937
Dendroaspis natriuretic peptide binds to the natriuretic peptide clearance receptorQ80255770
Distinct roles for renal particulate and soluble guanylyl cyclases in preserving renal function in experimental acute heart failureQ80725402
C-type natriuretic peptide, a novel antifibrotic and antihypertrophic agent, prevents cardiac remodeling after myocardial infarctionQ81397064
Multicenter prospective investigation on efficacy and safety of carperitide for acute heart failure in the 'real world' of therapyQ81441501
P433issue191
P921main subjectheart failureQ181754
P304page(s)485-506
P577publication date2009-01-01
P1433published inHandbook of experimental pharmacologyQ26841924
P1476titleModulation of cGMP in heart failure: a new therapeutic paradigm

Reverse relations

cites work (P2860)
Q34141284A nanoparticle delivery vehicle for S-nitroso-N-acetyl cysteine: sustained vascular response
Q35994136Adenoviral short hairpin RNA therapy targeting phosphodiesterase 5a relieves cardiac remodeling and dysfunction following myocardial infarction
Q38155422Changes in renal function in congestive heart failure
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Q37416187The role of exercise on L-arginine nitric oxide pathway in chronic heart failure
Q57152438Upregulation of Myocardial and Vascular Phosphodiesterase 9A in A Model of Atherosclerotic Cardiovascular Disease

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