Cardiomyocyte DNA synthesis and binucleation during murine development

scientific article published on 01 November 1996

Cardiomyocyte DNA synthesis and binucleation during murine development is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.1996.271.5.H2183
P698PubMed publication ID8945939

P2093author name stringK K Kim
L J Field
M Franklin
M H Soonpaa
L Pajak
P433issue5 Pt 2
P407language of work or nameEnglishQ1860
P304page(s)H2183-9
P577publication date1996-11-01
P1433published inAmerican Journal of PhysiologyQ2160146
P1476titleCardiomyocyte DNA synthesis and binucleation during murine development
P478volume271

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cites work (P2860)
Q90117962A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation
Q26827943A neonatal blueprint for cardiac regeneration
Q33835461A proliferative burst during preadolescence establishes the final cardiomyocyte number.
Q41026763A tail of translational regulation
Q36709796APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart
Q35789287Adaptive mechanisms to compensate for overnutrition-induced cardiovascular abnormalities
Q37375494Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo
Q33684123Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis.
Q34276940Akt/protein kinase B promotes organ growth in transgenic mice
Q94554709Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy
Q34807247Alpha-catenins control cardiomyocyte proliferation by regulating Yap activity
Q33600984Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development
Q37136956An extensive genetic program occurring during postnatal growth in multiple tissues
Q44355553Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes.
Q64091759Bioengineering adult human heart tissue: How close are we?
Q34995850Blockade of EMAP II protects cardiac function after chronic myocardial infarction by inducing angiogenesis
Q27321854Bmi1 (+) cardiac progenitor cells contribute to myocardial repair following acute injury
Q26765120Building and re-building the heart by cardiomyocyte proliferation
Q39990000CMF1-Rb interaction promotes myogenesis in avian skeletal myoblasts
Q41488348CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Q38835689Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility
Q36146340Cardiac Regeneration and Stem Cells.
Q38743894Cardiac Regeneration: Lessons From Development
Q43152071Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling
Q34162142Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.
Q38615286Cardiac injury of the newborn mammalian heart accelerates cardiomyocyte terminal differentiation.
Q34571536Cardiac molecular-acclimation mechanisms in response to swimming-induced exercise in Atlantic salmon
Q36788885Cardiac myocyte cell cycle control in development, disease, and regeneration
Q35895661Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.
Q36349782Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
Q35619146Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation
Q39360699Cardiac regeneration strategies: Staying young at heart.
Q37866145Cardiac regeneration: different cells same goal
Q38673647Cardiac stem cells for myocardial regeneration: promising but not ready for prime time
Q36051051Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy
Q64376951Cardiomyocyte Proliferation for Therapeutic Regeneration
Q50455506Cardiomyocyte Proliferation: Teaching an Old Dogma New Tricks
Q41470022Cardiomyocyte cell cycle activation ameliorates fibrosis in the atrium
Q90671484Cardiomyocyte cell cycle dynamics and proliferation revealed through cardiac-specific transgenesis of fluorescent ubiquitinated cell cycle indicator (FUCCI)
Q89519147Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine
Q36567874Cardiomyocyte proliferation contributes to heart growth in young humans
Q38998289Cardiomyocyte proliferation in zebrafish and mammals: lessons for human disease
Q36802647Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis.
Q37056105Cardiomyocyte-specific endothelin A receptor knockout mice have normal cardiac function and an unaltered hypertrophic response to angiotensin II and isoproterenol.
Q35700881Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development
Q35184063Cell cycle regulation to repair the infarcted myocardium.
Q38809842Cell migration during heart regeneration in zebrafish
Q37429909Cell-cycle-based strategies to drive myocardial repair
Q38059068Challenges measuring cardiomyocyte renewal
Q98881867Characterization of iCell cardiomyocytes using single-cell RNA-sequencing methods
Q52562672Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach.
Q27303582Ciona as a Simple Chordate Model for Heart Development and Regeneration
Q36836276Classic "broken cell" techniques and newer live cell methods for cell cycle assessment
Q27302374Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling
Q37368118Cyclin D1 overexpression promotes cardiomyocyte DNA synthesis and multinucleation in transgenic mice
Q33762022DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint
Q91891412Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes
Q50278171Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development
Q89180458Development, Proliferation, and Growth of the Mammalian Heart
Q35970462Developmental alterations in centrosome integrity contribute to the post-mitotic state of mammalian cardiomyocytes
Q44237521Developmental toxicity of terbutaline: critical periods for sex-selective effects on macromolecules and DNA synthesis in rat brain, heart, and liver
Q42407025Dexamethasone Induces Cardiomyocyte Terminal Differentiation via Epigenetic Repression of Cyclin D2 Gene
Q64062683Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period
Q35118442Differential regenerative capacity of neonatal mouse hearts after cryoinjury.
Q37259559Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart
Q90044677Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies
Q36854692Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo
Q59133041Does cardiac development provide heart research with novel therapeutic approaches?
Q92447818Down-regulation of MEIS1 promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes
Q35900967Downregulation of doxorubicin-induced myocardial apoptosis accompanies postnatal heart maturation
Q27304839Dynamic Alterations to α-Actinin Accompanying Sarcomere Disassembly and Reassembly during Cardiomyocyte Mitosis
Q33701814EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration
Q36846737Early fetal hypoxia leads to growth restriction and myocardial thinning
Q73400458Effect of maternal chronic hypoxic exposure during gestation on apoptosis in fetal rat heart
Q51102078Effects of β-adrenergic receptor drugs on embryonic ventricular cell proliferation and differentiation and their impact on donor cell transplantation
Q26782516Endocrine and other physiologic modulators of perinatal cardiomyocyte endowment
Q38189970Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth.
Q36867184Endothelial Nogo-B regulates sphingolipid biosynthesis to promote pathological cardiac hypertrophy during chronic pressure overload
Q30574106Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes
Q33391392Enhanced proliferation of monolayer cultures of embryonic stem (ES) cell-derived cardiomyocytes following acute loss of retinoblastoma
Q39016129Evolving approaches to heart regeneration by therapeutic stimulation of resident cardiomyocyte cell cycle.
Q33790139Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice
Q64060687Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate but Does Not Change Cardiomyocyte Number in Infant Mice
Q33321972Forced expression of the cell cycle inhibitor p57Kip2 in cardiomyocytes attenuates ischemia-reperfusion injury in the mouse heart
Q28576534Forced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytes
Q46345451Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration
Q93241553From pediatrics to geriatrics: Mechanisms of heart failure across the life-course
Q34504097Functional screening identifies miRNAs inducing cardiac regeneration.
Q35543454GATA6 reporter gene reveals myocardial phenotypic heterogeneity that is related to variations in gap junction coupling.
Q48641170Gender differences in the expression of genes involved during cardiac development in offspring from dams on high fat diet.
Q37369799Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.
Q88876248Genetic insights into mammalian heart regeneration
Q64944906Genetics of and pathogenic mechanisms in arrhythmogenic right ventricular cardiomyopathy.
Q42787685Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest
Q36540656Getting to the heart of myocardial stem cells and cell therapy
Q38201071Harnessing the power of dividing cardiomyocytes
Q48136151Heart regeneration and the cardiomyocyte cell cycle.
Q89870117Heart regeneration in mouse and human: A bioengineering perspective
Q38640560Hypoxia Induced Myocardial Regeneration
Q47570037Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart
Q49572546Impact of preterm birth on the developing myocardium of the neonate.
Q37713958In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease
Q28591790Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice
Q88664220Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo
Q91963816Inhibition of Senescence-Associated Genes Rb1 and Meis2 in Adult Cardiomyocytes Results in Cell Cycle Reentry and Cardiac Repair Post-Myocardial Infarction
Q28393594Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling
Q37376097Insights into the characteristics of mammalian cardiomyocyte terminal differentiation shown through the study of mice with a dysfunctional c-kit
Q38402231Isolation of cardiomyocyte nuclei from post-mortem tissue
Q46707882Isolation, Culture and Transduction of Adult Mouse Cardiomyocytes
Q89936490Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration
Q33985918Limitations of conventional approaches to identify myocyte nuclei in histologic sections of the heart
Q91586255Limited Regeneration Potential with Minimal Epicardial Progenitor Conversions in the Neonatal Mouse Heart after Injury
Q36621873Mechanisms of Cardiac Regeneration
Q39129349Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration
Q33509740Mechanobiology of cardiomyocyte development
Q38161836MicroRNAs in myocardial ischemia: identifying new targets and tools for treating heart disease. New frontiers for miR-medicine.
Q36124189Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction.
Q36225991Mid-gestation ovine cardiomyocytes are vulnerable to mitotic suppression by thyroid hormone
Q42778087Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation
Q36933190Model systems for cardiovascular regenerative biology
Q90527191Molecular mechanisms of heart regeneration
Q64907860Molecular switch model for cardiomyocyte proliferation.
Q92535720Mono- and multi-nucleated ventricular cardiomyocytes constitute a transcriptionally homogenous cell population
Q90296263Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling
Q93075062Mouse HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury
Q38667300Multi-Cellular Transcriptional Analysis of Mammalian Heart Regeneration
Q91975933Multicellular In vitro Models of Cardiac Arrhythmias: Focus on Atrial Fibrillation
Q42943390Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth
Q38840384Mutations in Alström protein impair terminal differentiation of cardiomyocytes
Q54857362Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration.
Q52730089Myocardial Polyploidization Creates a Barrier to Heart Regeneration in Zebrafish.
Q64084759Myocardial lipofuscin accumulation in ageing and sudden cardiac death
Q55547891Near to One's Heart: The Intimate Relationship Between the Placenta and Fetal Heart.
Q55022347Neonatal Apex Resection Triggers Cardiomyocyte Proliferation, Neovascularization and Functional Recovery Despite Local Fibrosis.
Q88576118Neonatal Growth Restriction Slows Cardiomyocyte Development and Reduces Adult Heart Size
Q90667654Neonatal Heart Regeneration: Comprehensive Literature Review
Q30842578Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window
Q57176905New Myocyte Formation in the Adult Heart: Endogenous Sources and Therapeutic Implications
Q37581016New Trends in Heart Regeneration: A Review
Q28395671New functions for alpha-catenins in health and disease: from cancer to heart regeneration
Q90215796Non-sarcomeric causes of heart failure
Q52105907Novel 3D culture system for study of cardiac myocyte development
Q46392627Novel large-particle FACS purification of adult ventricular myocytes reveals accumulation of myosin and actin disproportionate to cell size and proteome in normal post-weaning development
Q34399422Onset and organ specificity of Tk2 deficiency depends on Tk1 down-regulation and transcriptional compensation
Q37628341Origin of cardiac fibroblasts and the role of periostin
Q33496782Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro
Q28589677Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth
Q64969028Overexpression of miR-221 in sudden death with cardiac hypertrophy patients.
Q41967457Overlapping roles of pocket proteins in the myocardium are unmasked by germ line deletion of p130 plus heart-specific deletion of Rb.
Q47128640Pathophysiology and therapeutic potential of cardiac fibrosis
Q41807478Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart
Q61851592Placental insufficiency decreases cell cycle activity and terminal maturation in fetal sheep cardiomyocytes
Q37171669Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system
Q30515858Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation
Q35146605Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins.
Q42045721Postnatal telomere dysfunction induces cardiomyocyte cell-cycle arrest through p21 activation
Q39750341Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A.
Q48161324REST regulates the cell cycle for cardiac development and regeneration.
Q92249257Rat Left Ventricular Cardiomyocytes Characterization in the Process of Postinfarction Myocardial Remodeling
Q38987181Redirecting cardiac growth mechanisms for therapeutic regeneration
Q28587025Redox Regulation of Heart Regeneration: An Evolutionary Tradeoff
Q38226891Redox signaling in cardiac renewal
Q43068017Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion
Q43088039Regulation of RNA polymerase III transcription during hypertrophic growth
Q35704292Regulation of microRNA during cardiomyocyte maturation in sheep.
Q35032442Regulation of the cardiomyocyte population in the developing heart
Q34073977Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes
Q50204070Resident fibroblast expansion during cardiac growth and remodeling.
Q89682690Reviewing the Limitations of Adult Mammalian Cardiac Regeneration: Noncoding RNAs as Regulators of Cardiomyogenesis
Q36552350Revisiting Cardiac Cellular Composition
Q38220004Sca-1+ cardiac progenitor cells and heart-making: a critical synopsis.
Q37344589Sca1-derived cells are a source of myocardial renewal in the murine adult heart.
Q92153120Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine
Q37000868Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt
Q51767161Short telomeres - A hallmark of heritable cardiomyopathies.
Q92198062Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart
Q37291483Sirolimus affects cardiomyocytes to reduce left ventricular mass in heart transplant recipients
Q38857890Striated muscle function, regeneration, and repair
Q36899914Substrate stiffness affects the functional maturation of neonatal rat ventricular myocytes
Q37466162T-type Ca²⁺ channels regulate the exit of cardiac myocytes from the cell cycle after birth.
Q38194552TWEAK-Fn14 Cytokine-Receptor Axis: A New Player of Myocardial Remodeling and Cardiac Failure
Q35105683Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.
Q27318593Targeted inactivation of Cerberus like-2 leads to left ventricular cardiac hyperplasia and systolic dysfunction in the mouse
Q28315028Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy
Q89880036Telomeres and Telomerase in Heart Ontogenesis, Aging and Regeneration
Q50333784The Biological Role of Nestin(+)-Cells in Physiological and Pathological Cardiovascular Remodeling
Q40496170The EAPC EXPERT tool.
Q36246110The conserved phosphoinositide 3-kinase pathway determines heart size in mice
Q26830787The dynamic role of cardiac fibroblasts in development and disease
Q50852735The extracellular matrix protein agrin promotes heart regeneration in mice
Q55279807The local microenvironment limits the regenerative potential of the mouse neonatal heart.
Q33924341The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response
Q35227826The periconceptional environment and cardiovascular disease: does in vitro embryo culture and transfer influence cardiovascular development and health?
Q62890059The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults
Q36042588The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation
Q37617998The transcription factor GATA4 promotes myocardial regeneration in neonatal mice
Q59128840Therapeutic approaches for cardiac regeneration and repair
Q64084317Three in a Box: Understanding Cardiomyocyte, Fibroblast, and Innate Immune Cell Interactions to Orchestrate Cardiac Repair Processes
Q43151809Thyroid hormone does not induce maturation of embryonic chicken cardiomyocytes in vitro
Q35648029Thyroid hormone drives fetal cardiomyocyte maturation
Q36051497Timing of cardiomyocyte growth, maturation, and attrition in perinatal sheep.
Q40425477Tissue-Specific Cell Cycle Indicator Reveals Unexpected Findings for Cardiac Myocyte Proliferation
Q90561720Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency
Q35132619Transcriptional reversion of cardiac myocyte fate during mammalian cardiac regeneration.
Q40099424Transgenic systems for unequivocal identification of cardiac myocyte nuclei and analysis of cardiomyocyte cell cycle status
Q27320040Trpm4 gene invalidation leads to cardiac hypertrophy and electrophysiological alterations
Q34356150Unexpected maturation of PI3K and MAPK-ERK signaling in fetal ovine cardiomyocytes
Q61796190Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition
Q38110436Vitamin D deficiency in early life and the potential programming of cardiovascular disease in adulthood.
Q104070077What we know about cardiomyocyte dedifferentiation
Q37341418Young developmental age cardiac extracellular matrix promotes the expansion of neonatal cardiomyocytes in vitro
Q90345265Zebrafish heart regeneration: Factors that stimulate cardiomyocyte proliferation
Q28595050c-kit is required for cardiomyocyte terminal differentiation
Q37682360p53 regulates the cardiac transcriptome.
Q52375225α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart.
Q38294845β-myosin heavy chain is induced by pressure overload in a minor subpopulation of smaller mouse cardiac myocytes

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