| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0091-6749(95)70128-1 |
| P698 | PubMed publication ID | 7722165 |
| P2093 | author name string | J Liu | |
| K W Kim | |||
| J V Fahy | |||
| H A Boushey | |||
| P2860 | cites work | Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum | Q24556580 |
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| Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells | Q34244537 | ||
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| Pus, deoxyribonucleic acid, and sputum viscosity | Q36451388 | ||
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| Kinins are generated during experimental rhinovirus colds | Q44639969 | ||
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| Death in Asthmatics. | Q55457012 | ||
| Recombinant human DNase inhalation in normal subjects and patients with cystic fibrosis. A phase 1 study | Q61850148 | ||
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| A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis | Q68062090 | ||
| Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma | Q68121516 | ||
| Interleukin-6 is released in the cutaneous response to allergen challenge in atopic individuals | Q68121519 | ||
| Nasal-secretion leukocyte populations determined by flow cytometry during acute rhinovirus infection | Q69838997 | ||
| Sputum and blood eosinophils during corticosteroid treatment of acute exacerbations of asthma | Q71123814 | ||
| Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? | Q72918047 | ||
| P433 | issue | 4 | |
| P921 | main subject | asthma | Q35869 |
| sputum | Q259346 | ||
| P1104 | number of pages | 10 | |
| P304 | page(s) | 843-852 | |
| P577 | publication date | 1995-04-01 | |
| P1433 | published in | The Journal of Allergy and Clinical Immunology | Q7743550 |
| P1476 | title | Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation | |
| P478 | volume | 95 |
| Q35888771 | A large subgroup of mild-to-moderate asthma is persistently noneosinophilic |
| Q37466238 | A rat model of picornavirus-induced airway infection and inflammation |
| Q40812281 | AT-RvD1 modulates CCL-2 and CXCL-8 production and NF-κB, STAT-6, SOCS1, and SOCS3 expression on bronchial epithelial cells stimulated with IL-4. |
| Q49389846 | ATP12A promotes mucus dysfunction during Type 2 airway inflammation |
| Q37315359 | Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype |
| Q37115894 | Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: current and future perspectives. |
| Q35088224 | Airway hyperresponsiveness: a story of mice and men and cytokines |
| Q30438572 | Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma |
| Q33723578 | Airway mucus function and dysfunction |
| Q28390215 | Allergic Responses Induced by a Fungal Biopesticide Metarhizium anisopliae and House Dust Mite Are Compared in a Mouse Model |
| Q51663541 | An adult model of exclusive viral wheeze: inflammation in the upper and lower respiratory tracts. |
| Q60409294 | An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness. |
| Q35534841 | Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids |
| Q43887850 | Analysis of sputum taken from wheezy and asthmatic infants and children, with special reference to respiratory infections |
| Q42538134 | Anti-oxidative effects of theophylline on human neutrophils involve cyclic nucleotides and protein kinase A. |
| Q36176942 | Apolipoprotein A-I attenuates ovalbumin-induced neutrophilic airway inflammation via a granulocyte colony-stimulating factor-dependent mechanism |
| Q44534202 | Are rhinovirus-induced airway responses in asthma aggravated by chronic allergen exposure? |
| Q43962892 | Association of forced expiratory volume with disease duration and sputum neutrophils in chronic asthma |
| Q39468965 | Association of rhinovirus infections with asthma |
| Q57416135 | Asthma |
| Q39423972 | Asthma Exacerbations: Pathogenesis, Prevention, and Treatment |
| Q47169950 | Asthma biomarkers in the age of biologics |
| Q36606687 | Asthma exacerbations . 3: Pathogenesis. |
| Q60155032 | Asthma in the elderly |
| Q30425168 | Asthma outcomes: biomarkers |
| Q34833093 | Basic mechanisms of asthma |
| Q34594817 | Blood neutrophil activation markers in severe asthma: lack of inhibition by prednisolone therapy |
| Q36140977 | Bromodomain and Extra Terminal (BET) Inhibitor Suppresses Macrophage-Driven Steroid-Resistant Exacerbations of Airway Hyper-Responsiveness and Inflammation. |
| Q46576806 | Bronchial exudate of serum proteins during asthma attack |
| Q36225732 | Bronchial mucosal inflammation and upregulation of CXC chemoattractants and receptors in severe exacerbations of asthma |
| Q35563589 | CCL7 and IRF-7 Mediate Hallmark Inflammatory and IFN Responses following Rhinovirus 1B Infection |
| Q47096199 | Caspase-1 deficiency reduces eosinophilia and interleukin-33 in an asthma exacerbation model |
| Q56501445 | Characterization of a population of small macrophages in induced sputum of patients with chronic obstructive pulmonary disease and healthy volunteers |
| Q36807456 | Chemokines and their receptors as potential targets for the treatment of asthma |
| Q34073570 | Chronic inflammation and asthma |
| Q33838131 | Clinical effectiveness and safety of montelukast in asthma. What are the conclusions from clinical trials and meta-analyses? |
| Q92340526 | Co-exposure to lipopolysaccharide and desert dust causes exacerbation of ovalbumin-induced allergic lung inflammation in mice via TLR4/MyD88-dependent and -independent pathways |
| Q38782680 | Comparing clinical efficacy of Symbicort versus Pulmicort in reducing asthma symptom and improving its control |
| Q42423633 | Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma |
| Q73229849 | Conditions in blood sampling procedures that extend the ex vivo stability of eosinophil activity markers in peripheral blood from allergic patients and healthy controls |
| Q35857943 | Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways. |
| Q37707616 | Detection and monitoring of localized matrix metalloproteinase upregulation in a murine model of asthma |
| Q35878506 | Differences in airway remodeling between asthma and chronic obstructive pulmonary disease |
| Q34197997 | Difficult-to-control asthma management through the use of a specific protocol |
| Q46611279 | Dimethylfumarate Impairs Neutrophil Functions |
| Q24557477 | Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells |
| Q28588484 | Dual oxidase regulates neutrophil recruitment in allergic airways |
| Q34988445 | EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma |
| Q35535357 | Effects of inhaled tumour necrosis factor alpha in subjects with mild asthma |
| Q36413148 | Effects of obesity and weight loss on airway physiology and inflammation in asthma |
| Q51463806 | Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial. |
| Q41955516 | Endothelial cell prostaglandin I(2) and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A(2)beta knockout mouse |
| Q78179414 | Eosinophilic inflammation assessed by induced sputum in corticosteroid-dependent asthma |
| Q36570169 | Exacerbations of asthma without sputum eosinophilia |
| Q35537039 | Exhaled breath condensate pH and exhaled nitric oxide in allergic asthma and in cystic fibrosis |
| Q64981659 | Group 2 Innate Lymphoid Cells in Respiratory Allergic Inflammation. |
| Q60949714 | HRV16 Impairs Macrophages Cytokine Response to a Secondary Bacterial Trigger |
| Q34048095 | Haemophilus influenzae infection drives IL-17-mediated neutrophilic allergic airways disease |
| Q35218066 | Host defense function of the airway epithelium in health and disease: clinical background |
| Q37327666 | Host immune responses to rhinovirus: mechanisms in asthma |
| Q44399977 | House Dust Mite Der p 1 Downregulates Defenses of the Lung by Inactivating Elastase Inhibitors |
| Q37711402 | Human airway smooth muscle cells from asthmatic individuals have CXCL8 hypersecretion due to increased NF-kappa B p65, C/EBP beta, and RNA polymerase II binding to the CXCL8 promoter |
| Q36079964 | Human asthma phenotypes: from the clinic, to cytokines, and back again |
| Q35221784 | Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism |
| Q36837862 | Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice |
| Q44633512 | Hyaluronan blocks human neutrophil elastase (HNE)-induced airway responses in sheep |
| Q37265367 | Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model |
| Q36992643 | IL-17-producing peripheral blood CD177+ neutrophils increase in allergic asthmatic subjects |
| Q47549656 | IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation. |
| Q47098828 | Immunotherapeutic efficacy of liposome-encapsulated refined allergen vaccines against Dermatophagoides pteronyssinus allergy |
| Q36201579 | Impact of smoking on asthma therapy: a critical review of clinical evidence |
| Q42780443 | Important role of neutrophils in the late asthmatic response in mice |
| Q42264569 | Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways. |
| Q37505259 | Increases in airway eosinophilia and a th1 cytokine during the chronic asymptomatic phase of asthma |
| Q33243274 | Induction of release and up-regulated gene expression of interleukin (IL)-8 in A549 cells by serine proteinases |
| Q28350179 | Inflammatory cell distribution in guinea pig airways and its relationship to airway reactivity |
| Q36203075 | Inflammatory cells in the airways in COPD. |
| Q35609170 | Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients |
| Q46957510 | Inhibition of allergen-induced pulmonary responses by the selective tryptase inhibitor 1,5-bis-[4-[(3-carbamimidoyl-benzenesulfonylamino)-methyl]-phenoxy]-pen tane (AMG-126737). |
| Q44741233 | Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness |
| Q34029144 | Inhibitory effects of inhaled complex traditional Chinese medicine on early and late asthmatic responses induced by ovalbumin in sensitized guinea pigs |
| Q45847690 | Interleukin (IL)-4 induces production of cytokine-induced neutrophil chemoattractants (CINCs) and intercellular adhesion molecule (ICAM)-1 in lungs of asthmatic rats |
| Q82123821 | Interleukin-18-deficient mice exhibit diminished chronic inflammation and airway remodelling in ovalbumin-induced asthma model |
| Q47736413 | Leukocyte counts in hypertonic saline-induced sputum in subjects with occupational asthma |
| Q28587885 | Leukotriene B4 levels in sputum from asthma patients |
| Q35528312 | Lower airway rhinovirus burden and the seasonal risk of asthma exacerbation |
| Q34166534 | Lower respiratory tract infection induced by a genetically modified picornavirus in its natural murine host |
| Q51030656 | MUC18 regulates IL-13-mediated airway inflammatory response. |
| Q37160335 | Mast cell tryptase and asthma |
| Q35804444 | Mast cell-derived TNF can promote Th17 cell-dependent neutrophil recruitment in ovalbumin-challenged OTII mice |
| Q33808131 | Mechanisms of occupational asthma |
| Q41510155 | Mechanisms of virus induced exacerbations of asthma |
| Q36745737 | Mechanisms of virus-induced asthma exacerbations: state-of-the-art. A GA2LEN and InterAirways document. |
| Q90124399 | Meeting the Challenge of Identifying New Treatments for Type 2-Low Neutrophilic Asthma |
| Q73815986 | Mixed effects of TGF-beta on human airway epithelial-cell chemokine responses |
| Q64072479 | Modeling the pasture-associated severe equine asthma bronchoalveolar lavage fluid proteome identifies molecular events mediating neutrophilic airway inflammation |
| Q34483166 | Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines |
| Q34773489 | Monitoring inflammation in CF. Cytokines |
| Q64235864 | NETopathic Inflammation in Chronic Obstructive Pulmonary Disease and Severe Asthma |
| Q34584541 | Nasal lavage VEGF and TNF-α levels during a natural cold predict asthma exacerbations |
| Q57463855 | Nebulised -Acetylcysteine for Unresponsive Bronchial Obstruction in Allergic Brochopulmonary Aspergillosis: A Case Series and Review of the Literature |
| Q49154648 | Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation |
| Q42764456 | Neutrophil airway inflammation in childhood asthma |
| Q38511107 | Neutrophil elastase causes MUC5AC mucin synthesis via EGF receptor, ERK and NF-kB pathways in A549 cells |
| Q36228230 | Neutrophil histamine contributes to inflammation in mycoplasma pneumonia |
| Q38645834 | Neutrophilic Inflammation in Asthma and Association with Disease Severity |
| Q34778056 | Neutrophilic airway inflammation and IL-17. |
| Q88229803 | Neutrophilic asthma: a distinct target for treatment? |
| Q36994670 | Neutrophils in asthma |
| Q46921876 | Nitric oxide production by polymorphonuclear leucocytes in infected cystic fibrosis sputum consumes oxygen |
| Q42764623 | Non-eosinophilic asthma and the innate immune response |
| Q28394141 | Non-eosinophilic asthma: importance and possible mechanisms |
| Q38756064 | Novel approaches to the management of noneosinophilic asthma |
| Q78700475 | Of mice and men |
| Q34502282 | Onset and outcome of asthma in older adults. A clinician's perspective |
| Q34159886 | Overlap Between Asthma and COPD: Where the Two Diseases Converge |
| Q41813669 | Oxidative stress augments toll-like receptor 8 mediated neutrophilic responses in healthy subjects. |
| Q83558732 | PI3-kinase regulates eosinophil and neutrophil degranulation in patients with allergic rhinitis and allergic asthma irrespective of allergen challenge model |
| Q36169188 | Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. |
| Q34541136 | Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge |
| Q35599667 | Peripheral muscle strength and functional capacity in patients with moderate to severe asthma |
| Q45011744 | Physiopathology of inflammatory events in asthma |
| Q34423365 | Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness |
| Q38734006 | Protective role of Th17 cells in pulmonary infection |
| Q73569485 | Quantitative, rather than qualitative, differences in CD69 upregulation in human blood eosinophils upon activation with selected stimuli |
| Q90351920 | Question 3: Can we diagnose asthma in children under the age of 5 years? |
| Q37857701 | Reconstruction is not renovation - the role of remodeling in asthma |
| Q45338276 | Redox Regulation of Inflammatory Processes Is Enzymatically Controlled. |
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| Q52647351 | Reproducibility of a novel model of murine asthma-like pulmonary inflammation. |
| Q34448487 | Resolvins: natural agonists for resolution of pulmonary inflammation. |
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| Q37292433 | T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia. |
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