PI3-kinase regulates eosinophil and neutrophil degranulation in patients with allergic rhinitis and allergic asthma irrespective of allergen challenge model

scientific article published on 01 February 2012

PI3-kinase regulates eosinophil and neutrophil degranulation in patients with allergic rhinitis and allergic asthma irrespective of allergen challenge model is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1033238227
P356DOI10.1007/S10753-011-9309-5
P698PubMed publication ID21384093

P50authorMaria LampinenQ71071159
P2093author name stringChrister Janson
Marie Carlson
Gunnemar Stålenheim
Ingrid Stolt
Mary Kämpe
P2860cites workMonitoring the allergic inflammationQ28191435
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Experimental and seasonal exposure to birch pollen in allergic rhinitis and allergic asthma with regard to the inflammatory responseQ83364508
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Serum eosinophil granule proteins predict asthma risk in allergic rhinitisQ28306331
Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme releaseQ28571156
Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory SocietyQ29616361
Degranulation patterns of eosinophil granulocytes as determinants of eosinophil driven diseaseQ33943245
The eosinophil: the cell and its weapons, the cytokines, its locationsQ34513541
Phosphoinositide 3-kinase gamma: a key modulator in inflammation and allergyQ35053093
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Systemic and local eosinophil inflammation during the birch pollen season in allergic patients with predominant rhinitis or asthmaQ36326895
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Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteinsQ36944424
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Neutrophils and asthma.Q37622862
Release of granule proteins by eosinophils from allergic and nonallergic patients with eosinophilia on immunoglobulin-dependent activation.Q41160504
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The induction of eosinophil peroxidase release: improved methods of measurement and stimulationQ45042220
Neutrophilic airway inflammation is a main feature of induced sputum in nonatopic asthmatic children.Q45977125
Evidence for the activation of blood complement in Sephadex beads-induced lung inflammation in guinea pigsQ46338043
Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammationQ46463176
The effect of cationic charge on release of eosinophil mediatorsQ46613033
Tissue- and stimulus-dependent role of phosphatidylinositol 3-kinase isoforms for neutrophil recruitment induced by chemoattractants in vivoQ46891752
Eosinophils: biological properties and role in health and diseaseQ51960619
C3b-induced eosinophil degranulation involves PI3-kinases and is inhibited by protein kinase C activity.Q54622288
Degranulation of eosinophils from pollen-atopic patients with asthma is increased during pollen season†Q67485671
Secretion of granule proteins from eosinophils and neutrophils is increased in asthmaQ67912756
Increased bronchial hypersensitivity after early and late bronchial reactions provoked by allergen inhalationQ69927722
Mechanisms for eosinophil degranulation; release of the eosinophil cationic proteinQ70180253
CD11b/CD18 (Mac-1) is required for degranulation of human eosinophils induced by human recombinant granulocyte-macrophage colony-stimulating factor and platelet-activating factorQ71624306
A crucial role for beta 2 integrin in the activation of eosinophils stimulated by IgGQ71707102
Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbationQ72168683
Piecemeal degranulation of peripheral blood eosinophils: a study of allergic subjects during and out of the pollen seasonQ73038102
P433issue1
P921main subjectallergic rhinitisQ272436
allergic asthmaQ12301086
P304page(s)230-239
P577publication date2012-02-01
P1433published inInflammationQ2560341
P1476titlePI3-kinase regulates eosinophil and neutrophil degranulation in patients with allergic rhinitis and allergic asthma irrespective of allergen challenge model
P478volume35

Reverse relations

cites work (P2860)
Q33604866Expression profiling of differentiating eosinophils in bone marrow cultures predicts functional links between microRNAs and their target mRNAs
Q34241738Identification of JAK2 as a Mediator of FIP1L1-PDGFRA-Induced Eosinophil Growth and Function in CEL
Q48019225Phosphoinositide 3-Kinase in Asthma: Novel Roles and Therapeutic Approaches
Q53546584Profound blockade of T cell activation requires concomitant inhibition of different class I PI3K isoforms.
Q94591368Roles of PI3K pan-inhibitors and PI3K-δ inhibitors in allergic lung inflammation: a systematic review and meta-analysis
Q41565956Src-dependent EGFR transactivation regulates lung inflammation via downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine asthma model
Q89941183Study of atopic multimorbidity in subjects with rhinitis using multiplex allergen component analysis
Q33953902Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils

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