| scholarly article | Q13442814 |
| P2093 | author name string | L. Sottrup-Jensen | |
| S. Magnusson | |||
| T. E. Petersen | |||
| P2860 | cites work | Bulletin of the Johns Hopkins Hospital | Q27718094 |
| Characterization of alkylamine-sensitive site in alpha 2-macroglobulin | Q33972588 | ||
| Metal chelate affinity chromatography, a new approach to protein fractionation | Q33996883 | ||
| alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions | Q36200944 | ||
| Physical and chemical properties of human plasma β2-macroglobulin | Q39505132 | ||
| The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule | Q39571590 | ||
| Purification of human plasma α2 macroglobulin and α1 proteinase inhibitor using zinc chelate chromatography | Q39580663 | ||
| The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism | Q41510402 | ||
| The interaction of alpha2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases | Q41934670 | ||
| Thiol reduction of human α2-macroglobulin. The subunit structure | Q42127672 | ||
| Studies on human plasma alpha 2-macroglobulin-enzyme interactions. Evidence for proteolytic modification of the subunit chain structure | Q42836510 | ||
| Binding of anhydrotrypsin to α2-macroglobulin | Q42881054 | ||
| Covalent binding of proteinases in their reaction with α2-macroglobulin | Q42882255 | ||
| [37] Reaction of protein sulfhydryl groups with Ellman's reagent | Q47740296 | ||
| Uptake of proteinase-α-macroglobulin complexes by macrophages☆ | Q67348895 | ||
| Molecular alteration of alpha-2-macroglobulin by aliphatic amines | Q68407922 | ||
| Affinity chromatography of plasminogen | Q68872782 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | biochemistry | Q7094 |
| biophysics | Q7100 | ||
| cell biology | Q7141 | ||
| genetics | Q7162 | ||
| structural biology | Q908902 | ||
| P304 | page(s) | 275-279 | |
| P577 | publication date | 1980-12-01 | |
| P1433 | published in | FEBS Letters | Q1388051 |
| P1476 | title | A thiol-ester in alpha 2-macroglobulin cleaved during proteinase complex formation | |
| A thiol-ester in α2-macroglobulin cleaved during proteinase complex formation | |||
| P478 | volume | 121 |
| Q67655423 | 30 Affinity chromatography: Specialized techniques |
| Q24296312 | A novel protease inhibitor of the alpha2-macroglobulin family expressed in the human epidermis |
| Q73681856 | Aberrant forms of alpha(2)-macroglobulin purified from patients with multiple sclerosis |
| Q41666046 | Alpha 2-macroglobulin bait region variants. A role for the bait region in tetramer formation |
| Q72732179 | Alpha 2-macroglobulin: an introduction |
| Q24656054 | Alpha-2-macroglobulin functions as an inhibitor of fibrinolytic, clotting, and neutrophilic proteinases in sepsis: studies using a baboon model |
| Q72719058 | Alpha-macroglobulins: Enzyme-binding proteins modulating lymphocyte function |
| Q42119474 | Amino acid sequence around the thiol and reactive acyl groups of human complement component C4. |
| Q69099148 | Amino acid sequence around the thiolester of alpha 2-macroglobulin from plasma of the crayfish, Pacifastacus leniusculus |
| Q72691655 | Arming α2-macroglobulin with ricin A chain forms a cytotoxic conjugate that inhibits protein synthesis and kills human fibroblasts |
| Q72732226 | Autolytic fragmentation of complement components C3 and C4 and its relationship to covalent binding activity |
| Q38355345 | Binding of C3b proceeds by a transesterification reaction at the thiolester site |
| Q41961333 | Binding of lipoprotein lipase to alpha 2-macroglobulin |
| Q30464694 | Binding of platelet-derived growth factor-BB and transforming growth factor-β 1 to α2-macroglobulin in vitro and in vivo: comparison of receptor-recognized and non-recognized α2-macroglobulin conformations |
| Q42866748 | Binding of proteinases to human alpha 2-macroglobulin with its thioester bonds cleaved by methylamine in the presence of a thiol-group-cyanylating reagent |
| Q30311393 | Binding of transforming growth factor-beta 1 to methylamine-modified alpha 2-macroglobulin and to binary and ternary alpha 2-macroglobulin-proteinase complexes |
| Q67538604 | Characterization of carbohydrates in the alpha 2-macroglobulin receptor |
| Q72732284 | Chemical and structural modifications of alpha 2-macroglobulin: effects on receptor binding and endocytosis studied in an in vivo model |
| Q30470789 | Chemical modification of alpha2-macroglobulin to generate derivatives that bind transforming growth factor-beta with increased affinity |
| Q37672059 | Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. |
| Q72087159 | Comparison of conformational changes of pregnancy zone protein and human α2-macroglobulin, a study using hydrophobic affinity partitioning |
| Q41543681 | Conformation and protease binding activity of binary and ternary human alpha 2-macroglobulin-protease complexes |
| Q73636382 | Control of the classical and the MBL pathway of complement activation |
| Q68996415 | Covalent and non-covalent interaction of chymotrypsin with alpha 2-macroglobulin |
| Q43628758 | Covalent disulfide binding of human IL-1β to α2-macroglobulin: Inhibition by d-penicillamine |
| Q27759036 | Crystal structure of the receptor-binding domain of alpha 2-macroglobulin |
| Q30467886 | Differences in the binding of transforming growth factor beta 1 to the acute-phase reactant and constitutively synthesized alpha-macroglobulins of rat. |
| Q72694474 | Dissociability of enzyme-α2-macroglobulin complexes |
| Q30308620 | Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors |
| Q34534665 | Effect of methylamine and plasmin on the conformation of human alpha 2-macroglobulin as revealed by differential scanning calorimetric analysis |
| Q67658098 | Effect of methylamine on the reaction of .alpha.2-macroglobulin with enzymes |
| Q72712219 | Effect of modified alpha 2macroglobulin on leucocyte locomotion and chemotaxis |
| Q72752684 | Effects of pimozide and penfluridol on the binding and endocytosis of α2-macroglobulin-CH3NH2 by mouse peritoneal macrophages |
| Q67466531 | Electron microscopy of α2-macroglobulin with a thiol ester bound ligand |
| Q41542489 | Evidence for similar conformational changes in α2-macroglobulin on reaction with primary amines or proteolytic enzymes |
| Q67233030 | Evidence that lithium and ammonium ions enhance lipopolysaccharide stimulation of lymphoid cells by different mechanisms |
| Q40173671 | Evolution of Proteolytic Enzymes |
| Q41052254 | Functional expression of the chicken low density lipoprotein receptor-related protein in a mutant chinese hamster ovary cell line restores toxicity of Pseudomonas exotoxin A and degradation of alpha2-macroglobulin. |
| Q42120643 | Functional modifications of α2-macroglobulin by primary amines. Kinetics of inactivation of α2-macroglobulin by methylamine, and formation of anomalous complexes with trypsin |
| Q42854377 | Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site |
| Q72732218 | Generation and reactivity of "nascent" alpha 2-macroglobulin: localization of cross-links in alpha 2-macroglobulin-trypsin complex |
| Q72728809 | Human α2macroglobulin |
| Q41838678 | Identification of monomeric alpha-macroglobulin proteinase inhibitors in birds, reptiles, amphibians and mammals, and purification and characterization of a monomeric alpha-macroglobulin proteinase inhibitor from the American bullfrog Rana catesbeia |
| Q72728091 | Identification of “embryonin” as bovine alpha 2-macroglobulin |
| Q35208694 | Inactivation of factor XII active fragment in normal plasma. Predominant role of C-1-inhibitor |
| Q71642309 | Ineffectiveness of the inhibition of the main haemorrhagic metalloproteinase from Bothrops jararaca venom by its only plasma inhibitor, α2-macroglobulin |
| Q47740289 | Inhibition of a snake venom hemorrhagic metalloproteinase by human and rat alpha-macroglobulins |
| Q42138316 | Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered alpha 2-macroglobulin containing a furin recognition sequence in the bait region |
| Q72110337 | Interaction between human serum alpha 1-antichymotrypsin and human leukocyte cathepsin G. complex formation and production of a modified inhibitor |
| Q30441381 | Interaction of hemorrhagic metalloproteinases with human .alpha.2-macroglobulin |
| Q67703110 | Interaction of transforming growth factor-beta 1 with alpha 2-macroglobulin. Role in transforming growth factor-beta 1 clearance |
| Q72691443 | Interaction of α2-macroglobulin with trypsin, chymotrypsin, plasmin, and papain |
| Q72732186 | Intrinsic fluorescence analyses of structure-function relationships during alpha 2-macroglobulin-protease reactions |
| Q43600487 | Isolation and characterization of an alpha-macroglobulin from the gastropod mollusc Helix pomatia with tetrameric structure and preserved activity after methylamine treatment |
| Q41902557 | Isolation of active subforms of alpha 2-macroglobulin |
| Q28263949 | Isolation of rat serum alpha 1-microglobulin. Identification of a complex with alpha 1-inhibitor-3, a rat alpha 2-macroglobulin homologue |
| Q72739175 | Kinetics of association of human proteinases with human alpha 2-macroglobulin |
| Q74404454 | Kinetics of nonproteolytic incorporation of a protein ligand into thermally activated alpha 2-macroglobulin: evidence for a novel nascent state |
| Q41909264 | Kinetics of the reaction of thrombin and alpha 2-macroglobulin |
| Q42869224 | Ligand binding, conformational change and plasma elimination of human, mouse and rat α-macroglobulin proteinase inhibitors |
| Q46207609 | Limited mutations in full-length tetrameric human alpha2-macroglobulin abrogate binding of platelet-derived growth factor-BB and transforming growth factor-beta1. |
| Q42857321 | Limulus alpha 2-macroglobulin. First evidence in an invertebrate for a protein containing an internal thiol ester bond |
| Q53900850 | Localisation of the major reactive lysine residue involved in the self-crosslinking of proteinase-activated Limulus alpha 2-macroglobulin. |
| Q47440675 | Localization of epsilon-lysyl-gamma-glutamyl cross-links in five human alpha 2-macroglobulin-proteinase complexes. Nature of the high molecular weight cross-linked products |
| Q72694608 | Localization of the proteinase-induced thiol groups in α2-macroglobulin |
| Q36741529 | Lysosomal degradation of receptor-bound urokinase-type plasminogen activator is enhanced by its inhibitors in human trophoblastic choriocarcinoma cells |
| Q72644079 | Mechanism of proteinase complex formation with alpha 2-macroglobulin. Three modes of trypsin binding |
| Q42665049 | Methylamine-induced conformational change of alpha2-macroglobulin and its zinc(II) binding capacity. An X-ray scattering study |
| Q37529803 | Model of alpha 2-macroglobulin structure and function |
| Q42857357 | Mouse alpha-macroglobulin. Structure, function and a molecular model |
| Q37409910 | Multiple forms of complement C3 in trout that differ in binding to complement activators |
| Q42681475 | New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor. |
| Q72727158 | Non-productive activation of the proteinase binding sites of α2-macroglobulin on reaction of the inhibitor with matrix-linked trypsin |
| Q35587843 | Nucleotide sequence of cDNA encoding human alpha 2-macroglobulin and assignment of the chromosomal locus |
| Q70149147 | Ovostatin: a novel proteinase inhibitor from chicken egg white. II. Mechanism of inhibition studied with collagenase and thermolysin |
| Q24606288 | Partial primary structure of human pregnancy zone protein: extensive sequence homology with human alpha 2-macroglobulin |
| Q44303946 | Pregnancy zone protein: a re-evaluation of serum levels in healthy women and in women suffering from breast cancer or trophoblastic disease |
| Q72654071 | Primary and secondary cleavage sites in the bait region of α2 -macroglobulin |
| Q42243813 | Primary structure of human alpha 2-macroglobulin. I. Isolation of the 26 CNBr fragments, amino acid sequence of 13 small CNBr fragments, amino acid sequence of methionine-containing peptides, and alignment of all CNBr fragments |
| Q28630950 | Primary structure of human alpha 2-macroglobulin. V. The complete structure |
| Q72636452 | Primary structure of the 'bait' region for proteinases in alpha 2-macroglobulin. Nature of the complex |
| Q30469838 | Proteinases are isoform-specific regulators of the binding of transforming growth factor beta to alpha 2-macroglobulin |
| Q72640737 | Proteolytic cleavage sites on α2-macroglobulin resulting in proteinase binding are different for trypsin and staphylococcus aureus V-8 proteinase |
| Q36803610 | Purification and characterization of a tetrameric alpha-macroglobulin proteinase inhibitor from the gastropod mollusc Biomphalaria glabrata |
| Q41093399 | Purification and characterization of an alpha-macroglobulin proteinase inhibitor from the mollusc Octopus vulgaris |
| Q42210233 | Purification and characterization of human alpha 2-macroglobulin conformational variants by non-ideal high performance size-exclusion chromatography |
| Q60405787 | Purification of the human placental α2 -macroglobulin receptor |
| Q42862745 | Recognition of chylomicron remnants and β-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver α2-macroglobulin-recognition site |
| Q41540313 | Recognition of nucleophile-treated alpha 2-macroglobulin by the alveolar macrophage alpha-macroglobulin . protease complex receptor |
| Q93000136 | Recombinant production of human α2-macroglobulin variants and interaction studies with recombinant G-related α2-macroglobulin binding protein and latent transforming growth factor-β2 |
| Q70336586 | Regulation of Protease Activity |
| Q42874697 | Relation of internal thioesters to conformational change and receptor-recognition site in α2-macroglobulin complexes |
| Q71653705 | Role of Internal Thiol Esters in the α‐Macroglobulin‐Proteinase Binding Mechanisma |
| Q42114213 | Role of the scavenger receptor in the uptake of methylamine-activated α2-macroglobulin by rat liver |
| Q70090201 | Separation of serum proteins on a Fe3+-monohydroxamate adsorbent |
| Q36382084 | Sequence determination of the thiolester site of the fourth component of human complement. |
| Q72646939 | Sequence location of a putative transglutaminase crosslinking site in human α2-macroglobulin |
| Q72628978 | Sequence location of the reactive thiol ester in human alpha 2-macroglobulin |
| Q44758430 | Sequence similarity between α2-macroglobulin from the horseshoe crab, Limulus polyphemus, and proteins of the α2-macroglobulin family from mammals |
| Q67659134 | Sertoli cell synthesizes and secretes a protease inhibitor, .alpha.2-macroglobulin |
| Q68978102 | Specific fluorescent labeling of alpha 2-macroglobulin-bound proteases: accessibility and localization of their active site within the complex |
| Q42828955 | Specificity of the thioester-containing reactive site of human C3 and its significance to complement activation |
| Q67541502 | Spontaneous thioester bond formation in alpha 2-macroglobulin, C3 and C4 |
| Q38306515 | Stabilization of homogeneous preparations of pregnancy zone protein lyophilized in the presence of saccharose. Structural and functional studies |
| Q42143755 | Stoichiometry of reactions of alpha 2-macroglobulin with trypsin and chymotrypsin |
| Q72708993 | Structural arrangement in the α2 -macroglobulin-thrombin complex |
| Q72732296 | Structural arrangement of the proteinase binding sites in human alpha 2-macroglobulin |
| Q70336656 | Structure and Function of Natural Inhibitors as Antagonists of Proteinase Activities |
| Q27695619 | Structure of a bacterial α2-macroglobulin reveals mimicry of eukaryotic innate immunity |
| Q47323239 | Structure of alpha 2-macroglobulin from the arthropod Limulus polyphemus |
| Q41544456 | Structure of alpha 2-macroglobulin in solution and its interaction with proteases: an X-ray scattering study using the contrast variation method |
| Q30657443 | Structure of protease-cleaved Escherichia coli α-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment |
| Q50933705 | Subunit and primary structure of a mouse alpha-macroglobulin, a human α2-macroglobulin homologue |
| Q72732215 | Synthetic lactam and thiolactone models of protein metastable binding sites |
| Q40393742 | The Proteinase‐Binding Reaction of α2M |
| Q43830771 | The binding of human complement proteins C5, factor B, beta 1H and properdin to complement fragment C3b on zymosan |
| Q42855710 | The conformational changes of alpha 2-macroglobulin induced by methylamine or trypsin. Characterization by extrinsic and intrinsic spectroscopic probes |
| Q41824910 | The conversion of human complement component C5 into fragment C5b by the alternative-pathway C5 convertase |
| Q72752742 | The effect of zinc and other divalent cations on the structure and function of human α2-macroglobulin |
| Q38160849 | The fibrinolytic system in man. |
| Q72647412 | The reaction of alpha 2-macroglobulin-bound trypsin with soybean trypsin inhibitor |
| Q41544447 | The role of enzyme lysyl amino groups in the reaction with alpha 2-macroglobulin |
| Q41845988 | The structure around the thioester bond in bovine alpha 2-macroglobulin. Possible implications for the conformational stability of the inhibitor on thioester cleavage |
| Q72721323 | The α2 macroglobulin/thrombin interaction in the presence of hydroxylamine |
| Q40109132 | Theβ-Cys-γ-Glu thiolester bond in human C3, C4, andα 2-macroglobulin |
| Q36281685 | Third component of human complement: Localization of the internal thiolester bond |
| Q44567334 | Three-dimensional reconstruction of a complex of human α2-macroglobulin with monomaleimido nanogold (Au1.4nm) embedded in ice |
| Q52371314 | Three‐Dimensional Reconstruction of Human α2‐Macroglobulin and Refinement of the Localization of Thiol Ester Bonds with Monomaleimido Nanogolda |
| Q73483388 | Transforming growth factor-β-induced collagen synthesis by human liver myofibroblasts is inhibited by α2-macroglobulin |
| Q72644076 | Trypsin-induced activation of the thiol esters in α2-macroglobulin generates a short-lived intermediate (‘nascent’ α2M) that can react rapidly to incorporate not only methylamine or putrescine but also proteins lacking proteinase activity |
| Q41301968 | Very Low Density Lipoprotein Receptor Binds and Mediates Endocytosis of Urokinase-type Plasminogen Activator-Type-1 Plasminogen Activator Inhibitor Complex |
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