The pathogenesis of insulin-dependent diabetes mellitus

scientific article published on 01 November 1994

The pathogenesis of insulin-dependent diabetes mellitus is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1056/NEJM199411243312107
P698PubMed publication ID7969282

P50authorNoel K. MaclarenQ124236631
P2093author name stringAtkinson MA
P2860cites workDifferences in risk of insulin-dependent diabetes in offspring of diabetic mothers and diabetic fathersQ71401820
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)1428-1436
P577publication date1994-11-01
P1433published inThe New England Journal of MedicineQ582728
P1476titleThe pathogenesis of insulin-dependent diabetes mellitus
P478volume331

Reverse relations

cites work (P2860)
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Q73679321Efficacy of different Helicobacter pylori eradication regimens in patients affected by insulin-dependent diabetes mellitus
Q45883118Efficient gene delivery to human and rodent islets with double-stranded (ds) AAV-based vectors
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Q51104874Engineering and expression of the intracellular domain of insulinoma-associated tyrosine phosphatase (IA-2ic), a type 1 diabetes autoantigen, in plants.
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Q40869063HLA-DRB1 alleles contribute to determining the prognosis of Japanese diabetes mellitus positive for antibodies to glutamate decarboxylase
Q78161086HLA-DRB1*0403 is associated with dominant protection against IDDM in the general Dutch population and subjects with high-risk DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype
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Q35544053Hepatic Insulin Gene Therapy in Insulin-Dependent Diabetes Mellitus
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Q44468596IL-1beta, IFN-gamma and TNF-alpha increase vulnerability of pancreatic beta cells to autoimmune destruction
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Q79294755Juxtaglomerular apparatus T-cell infiltration affects glomerular structure in Type 1 diabetic patients
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Q35156175Lespedeza davurica (Lax.) Schindl. extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes
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Q37527795MRI as a tool to monitor islet transplantation
Q57188448MRI of insulitis in autoimmune diabetes
Q36526326Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement
Q85039092Maternal dietary n‐6/n‐3 fatty acid ratio affects type 1 diabetes development in the offspring of non‐obese diabetic mice
Q84006142Maternal intake of vitamin D during pregnancy and risk of advanced beta cell autoimmunity and type 1 diabetes in offspring
Q43110580Measurement of IgG levels can serve as a biomarker in newly diagnosed diabetic children
Q41628489Mechanisms underlying the loss of self tolerance in NOD mice
Q34444323Medical care from childhood to adulthood in type 1 and type 2 diabetes
Q35614319Medical myths involving diabetes
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Q38983706Metabolic syndrome in sub-Saharan Africa: "smaller twin" of a region's prostatic diseases?
Q38240129Modulation of diabetes-mellitus-induced male reproductive dysfunctions in experimental animal models with medicinal plants
Q37947597Molecular imaging: a promising tool to monitor islet transplantation
Q73734443Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart
Q35166486Myeloid-derived suppressor cells prevent type 1 diabetes in murine models
Q39774757Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.
Q37374258Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.
Q36147791NeuroD1 gene and interleukin-18 gene polymorphisms in type 1 diabetes in Dalmatian population of Southern Croatia
Q52566324Neutrophilic granulocytes are the predominant cell type infiltrating pancreatic islets in contact with ABO-compatible blood.
Q36065469New therapies for type 1 diabetes mellitus
Q40934999Newborn screening for HLA markers associated with IDDM: diabetes autoimmunity study in the young (DAISY).
Q40477828Nicotinamide and Diabetes Prevention
Q37096895Non-invasive detection of transplanted pancreatic islets
Q39660840Non-viral systemic delivery of Fas siRNA suppresses cyclophosphamide-induced diabetes in NOD mice
Q34983969Noninvasive imaging of islet grafts using positron-emission tomography
Q89719095Novel Mouse miRNA Chr13_novelMiR7354-5p Improves Bone-Marrow-Derived Mesenchymal Stem Cell Differentiation into Insulin-Producing Cells
Q37088197Novel biomarkers in type 1 diabetes
Q36853493Novel detection of pancreatic and duodenal homeobox 1 autoantibodies (PAA) in human sera using luciferase immunoprecipitation systems (LIPS) assay
Q33672280Novel therapeutic effects of sesamin on diabetes-induced cardiac dysfunction
Q49189362On type 1 diabetes mellitus pathogenesis
Q29393228Opinion: Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes
Q64268733Optimal Tolerogenic Dendritic Cells in Type 1 Diabetes (T1D) Therapy: What Can We Learn From Non-obese Diabetic (NOD) Mouse Models?
Q91778233Optimising the Benefits of SGLT2 Inhibitors for Type 1 Diabetes
Q41112023Pancreas transplantation: a managed cure approach to diabetes
Q34028055Pancreatic and islet transplantation
Q52893248Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes.
Q73674800Peptide-specific cytotoxicity of T lymphocytes against glutamic acid decarboxylase and insulin in type 1 diabetes mellitus
Q51095612Peripheral neuropathies in diabetes.
Q42000560Physical fitness in children with type 1 diabetes measured with six-minute walk test
Q36269185Polymeric delivery of therapeutic RAE-1 plasmid to the pancreatic islets for the prevention of type 1 diabetes
Q43596212Polymorphism in gene for islet autoantigen, IA-2, and type 1 diabetes in Japanese subjects
Q56905165Possible association between CTLA4 DNA polymorphisms and early onset type 1 diabetes in a UK population
Q38071770Potential role of mesenchymal stromal cells in pancreatic islet transplantation
Q35093549Prediabetes in children: natural history, diagnosis, and preventive strategies
Q35101668Protection against autoimmune diabetes by silkworm-produced GFP-tagged CTB-insulin fusion protein.
Q37308802Protection of nonobese diabetic mice from autoimmune diabetes by reduction of islet mass before insulitis
Q33592891Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
Q47347761Quality of life of patients with type I diabetes mellitus
Q36645596Radioiodinated naphthylalanine derivatives targeting pancreatic beta cells in normal and nonobese diabetic mice
Q46543844Regulatory T cell-associated activity in photopheresis-induced immune tolerance in recent onset type 1 diabetes children
Q44679781Relationship between glycemic control, ethnicity and socioeconomic status in Hispanic and white non-Hispanic youths with type 1 diabetes mellitus
Q37178859Relationships of DTI findings with neurocognitive dysfunction in children with Type 1 diabetes mellitus
Q41432895Reprogramming human gallbladder cells into insulin-producing β-like cells
Q26998424Role of nutritional factors at the early life stages in the pathogenesis and clinical course of type 1 diabetes
Q26782979Roles of Commensal Microbiota in Pancreas Homeostasis and Pancreatic Pathologies
Q34079225Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes
Q34991070Schizophrenia and diabetes
Q40473381Self and non-self antigen in diabetic autoimmunity: Molecules and mechanisms
Q38755624Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines
Q39265474Sensory nerve regeneration after epithelium wounding in normal and diabetic cornea.
Q77841517Serum IFN-gamma and IL-10 levels are associated with disease progression in non-obese diabetic mice
Q24623113Shared and distinct genetic variants in type 1 diabetes and celiac disease
Q78554047Similar incidence of type 1 diabetes in two ethnically different populations (Italy and Slovenia) is sustained by similar HLA susceptible/protective haplotype frequencies
Q45873999Simultaneous stimulation of Fas-mediated apoptosis and blockade of costimulation prevent autoimmune diabetes in mice induced by multiple low-dose streptozotocin
Q37015391Specific HLA-DRB and -DQB alleles and haplotypes confer disease susceptibility or resistance in Bahraini type 1 diabetes patients
Q36181700Spontaneous complete remission of type 1 diabetes mellitus in an adult - review and case report
Q84452304Study of interleukin-10 promoter region polymorphisms (-1082A/G, -819T/C and -592A/C) in type 1 diabetes mellitus in Turkish population
Q34629092Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit.
Q42035404Suppression of diabetes in non-obese diabetic (NOD) mice by oral administration of a cholera toxin B subunit-insulin B chain fusion protein vaccine produced in silkworm
Q40621226Suppressor mechanism of serum thymic factor on tumor necrosis factor-α-induced apoptosis in the mouse pancreatic β-cell line
Q52165714Survey of mRNAs encoding zinc transporters and other metal complexing proteins in pancreatic islets of rats from birth to adulthood: similar patterns in the Sprague-Dawley and Wistar BB strains.
Q73489749T cells and autoantibodies to human HSP70 in type 1 diabetes in children
Q41911811T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice
Q38917507TNFA-TNFB haplotypes modify susceptibility to type I diabetes mellitus independently of HLA class II in a Moroccan population
Q35579471TRAIL and DcR1 expressions are differentially regulated in the pancreatic islets of STZ- versus CY-applied NOD mice
Q41603351Tactics for type I diabetes
Q89477264Targeting Glycoproteins as a therapeutic strategy for diabetes mellitus and its complications
Q28214902The HLA class I A locus affects susceptibility to type 1 diabetes
Q52945572The IL12B 3' untranslated region DNA polymorphism is not associated with early-onset type 1 diabetes.
Q91738006The Role Of Adiponectin, TNF-α And Glutathione In The Pathogenesis And Evolution Of Type 1 Diabetes
Q39233053The Role of Dendritic Cell Maturation in the Induction of Insulin-Dependent Diabetes Mellitus
Q56902043The association of CTLA-4 and HLA class II autoimmune risk genotype with regulatory T cell marker expression in 5-year-old children
Q28215658The association of specific HLA class I and II alleles with type 1 diabetes among Filipinos
Q44796616The changing presentation of children with newly diagnosed type 1 diabetes mellitus.
Q40953976The clinical significance of an autoimmune response against glutamic acid decarboxylase
Q42001469The destructive action of IL-1alpha and IL-1beta in IDDM is a multistage process: evidence and confirmation by apoptotic studies, induction of intermediates and electron microscopy.
Q33752748The diagnosis and classification of diabetes mellitus in nonpregnant adults
Q43289250The effects of resveratrol on cyclooxygenase-1 and cyclooxygenase-2 mRNA and protein levels in diabetic rat kidneys
Q94562813The emerging roles of WBP2 oncogene in human cancers
Q36586011The identification of CD4+ T cell epitopes with dedicated synthetic peptide libraries
Q50740395The incidence of type 1 diabetes mellitus in Greek-Cypriot children and adolescents in 1990-2000.
Q36265212The influence of tobacco smoking on humoral immune response in insulin dependent diabetic pregnancy
Q52196097The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.
Q87135143The new insights from DPP-4 inhibitors: their potential immune modulatory function in autoimmune diabetes
Q71420898The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus
Q24675746The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS
Q37984231Toll-like receptors, the NLRP3 inflammasome, and interleukin-1β in the development and progression of type 1 diabetes
Q36823176Toward a model of memory enhancement in schizophrenia: glucose administration and hippocampal function
Q34359584Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence.
Q53928842Transfer of dendritic cells (DC) ex vivo stimulated with interferon-gamma (IFN-gamma) down-modulates autoimmune diabetes in non-obese diabetic (NOD) mice.
Q35837580Type 1 Diabetes Prevention in NOD Mice by Targeting DPPIV/CD26 Is Associated with Changes in CD8⁺T Effector Memory Subset
Q38130263Type 1 diabetes and celiac disease: The effects of gluten free diet on metabolic control
Q35216879Type 1 diabetes mellitus in patients with chronic hepatitis C before and after interferon therapy
Q33657633Type 1 diabetes, cardiovascular complications and sesame ( zhī má).
Q39425320Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire
Q34321603Type 1 diabetes: new perspectives on disease pathogenesis and treatment
Q33606814Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease
Q40439867Type I diabetes mellitus and pregnancy
Q39413871Up-regulation of small intestinal interleukin-17 immunity in untreated coeliac disease but not in potential coeliac disease or in type 1 diabetes
Q37634057Urinary biomarkers for the early diagnosis of retinopathy and nephropathy in type 1 diabetes mellitus: a "steady stream" of information using proteomics
Q42361533Vaccination and autoimmune diseases: is prevention of adverse health effects on the horizon?
Q33975703Vaccination strategies for mucosal immune responses
Q38184961Vascular imaging in diabetes
Q41641704Vasculitis and the nervous system. Historical perspective and overview
Q33852513Virus-induced immune dysregulation as a triggering factor for the development of drug rashes and autoimmune diseases: with emphasis on EB virus, human herpesvirus 6 and hepatitis C virus
Q36065477Viruses and diabetes: is there something sweet about hepatitis C infection?
Q38773655Vitamin D and diabetes mellitus: Causal or casual association?
Q24800803Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population
Q44249584Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in the Dalmatian population.
Q81470421[Molecular diagnosis of diabetes mellitus]
Q40728434beta-cell antigen-specific CD56(+) NKT cells from type 1 diabetic patients: autoaggressive effector T cells damage human CD56(+) beta cells by HLA-restricted and non-HLA-restricted pathways
Q96431014microRNA-181c-5p promotes the formation of insulin-producing cells from human induced pluripotent stem cells by targeting smad7 and TGIF2

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