T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice

scientific article published on July 1997

T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.186.2.299
P932PMC publication ID2198973
P698PubMed publication ID9221759
P5875ResearchGate publication ID13997359

P2093author name stringJ D Katz
M O Kurrer
S V Pakala
P2860cites workDevelopment of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophagesQ29618421
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Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destructionQ34134530
In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD miceQ34224719
Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi miceQ34238473
Pancreatic islet-specific T-cell clones from nonobese diabetic miceQ34313103
Anti-α/β T cell receptor monoclonal antibody provides an efficient therapy for autoimmune diabetes in nonobese diabetic (NOD) miceQ34750997
Beta cell apoptosis in T cell-mediated autoimmune diabetesQ35905815
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic miceQ36361909
Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic miceQ36363008
Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetesQ36366434
Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the diseaseQ36380402
Divergent effects of interleukin-10 on cytokine production by mononuclear phagocytes and endothelial cellsQ36773372
Insulin-dependent diabetes mellitusQ36970581
Identification of dying cells--in situ stainingQ40402397
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.Q40606547
Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation?Q40745649
Microcirculation of the islets of Langerhans. Long Beach Veterans Administration Regional Medical Education Center SymposiumQ40971495
Postnatal anti-interferon-gamma treatment prevents pancreatic inflammation in transgenic mice with beta-cell expression of interferon-gammaQ41032597
Induction of Th1 and Th2 CD4+ T cell responses: the alternative approachesQ41464299
Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibodyQ41816592
Loss of pancreatic islet tolerance induced by beta-cell expression of interferon-gammaQ43576523
Absence of insulitis and overt diabetes in athymic nude mice with NOD genetic background.Q44383562
Late complications of immune deviation therapy in a nonhuman primateQ46594595
Interleukin-10 drives human monocytes to CD16 positive macrophages.Q50335933
Immune regulation in type 1 diabetes.Q52048662
Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection.Q54214153
Predominance of T lymphocytes in pancreatic islets and spleen of pre-diabetic non-obese diabetic (NOD) mice: a longitudinal studyQ67298313
Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expressionQ68300729
Suppression of overt diabetes in NOD mice by anti-thymocyte serum or anti-Thy 1, 2 antibodyQ68812406
Following a diabetogenic T cell from genesis through pathogenesisQ70488192
Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cellsQ71829117
Complexities in the treatment of autoimmune diseaseQ71947990
Transgenic expression of IL-10 in pancreatic islet A cells accelerates autoimmune insulitis and diabetes in non-obese diabetic miceQ72109469
T helper cell subsets in insulin-dependent diabetesQ72265872
The pathogenesis of insulin-dependent diabetes mellitusQ72827807
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectacute pancreatitisQ854573
P304page(s)299-306
P577publication date1997-07-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleT helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice
P478volume186

Reverse relations

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