Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates

scientific article published on 01 October 1999

Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/JM980492E
P698PubMed publication ID10543872

P50authorMichael D. B. SwedbergQ42842832
P2093author name stringJ Lau
P D Suzdak
K E Andersen
H Petersen
B F Lundt
J L Sørensen
L J Knutsen
P O Huusfeldt
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)4281-4291
P577publication date1999-10-01
P1433published inJournal of Medicinal ChemistryQ900316
P1476titleSynthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates
P478volume42

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cites work (P2860)
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Q86938754Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives by Suzuki-Miyaura Cross-Coupling Reactions
Q51167808Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives with N-Arylalkynyl Substituents.
Q88679493Development of Positron Emission Tomography Radiotracers for the GABA Transporter 1
Q35393157Generation and screening of oxime libraries addressing the neuronal GABA transporter GAT1.
Q55665570Pairwise structural comparison of tiagabine analogs gives new insights into their protein binding modes.
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Q36686930Structure-activity relationship and pharmacology of gamma-aminobutyric acid (GABA) transport inhibitors.
Q43764148Synthesis of novel GABA uptake inhibitors. Part 6: preparation and evaluation of N-Omega asymmetrically substituted nipecotic acid derivatives

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