| scholarly article | Q13442814 |
| P356 | DOI | 10.4049/JIMMUNOL.165.10.5962 |
| P698 | PubMed publication ID | 11067959 |
| P2093 | author name string | B B Aggarwal | |
| A Mukhopadhyay | |||
| S K Manna | |||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | leflunomide | Q248550 |
| NF-κB | Q411114 | ||
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 5962-5969 | |
| P577 | publication date | 2000-11-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | Leflunomide suppresses TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis | |
| P478 | volume | 165 |
| Q38344733 | 5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-κB. |
| Q45066849 | A 771726, the active metabolite of leflunomide, inhibits TNF-alpha and IL-1 from Kupffer cells |
| Q43184299 | Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver |
| Q28394186 | Acquired resistance of human T cells to sulfasalazine: stability of the resistant phenotype and sensitivity to non-related DMARDs |
| Q34639939 | Activation of nuclear factor-κB in the brain after experimental subarachnoid hemorrhage and its potential role in delayed brain injury |
| Q36906008 | An update of teriflunomide for treatment of multiple sclerosis |
| Q40354910 | Anti-inflammatory effects of leflunomide in combination with methotrexate on co-culture of T lymphocytes and synovial macrophages from rheumatoid arthritis patients. |
| Q35552561 | Anti-inflammatory effects of leflunomide on cultured synovial macrophages from patients with rheumatoid arthritis |
| Q90271594 | Combination of leflunomide and benazepril reduces renal injury of diabetic nephropathy rats and inhibits high-glucose induced cell apoptosis through regulation of NF-κB, TGF-β and TRPC6 |
| Q34731287 | Current and future management approaches for rheumatoid arthritis |
| Q34752212 | Cytomegalovirus-mediated activation of pyrimidine biosynthesis drives UDP-sugar synthesis to support viral protein glycosylation |
| Q44432122 | Differential Control of Cell Cycle, Proliferation, and Survival of Primary T Lymphocytes by Purine and Pyrimidine Nucleotides |
| Q41849103 | Differential effects of leflunomide and methotrexate on cytokine production in rheumatoid arthritis |
| Q34462745 | Differential immunomodulatory effects by Tripterygium wilfordii Hook f-derived refined extract PG27 and its purified component PG490 (triptolide) in human peripheral blood T cells: potential therapeutics for arthritis and possible mechanisms explain |
| Q42955064 | Dual mycobacterial infection in the setting of leflunomide treatment for rheumatoid arthritis |
| Q41781500 | Effect of leflunomide on immunological liver injury in mice |
| Q43175836 | Effect of leflunomide on liver regeneration after partial hepatectomy in rats |
| Q33557886 | Geniposide inhibits high glucose-induced cell adhesion through the NF-kappaB signaling pathway in human umbilical vein endothelial cells |
| Q35600013 | Glia: a novel drug discovery target for clinical pain |
| Q36662024 | Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients |
| Q37602033 | IL-22-producing CD4+T cells in the treatment response of rheumatoid arthritis to combination therapy with methotrexate and leflunomide |
| Q41167409 | In vitro evaluation of physiologically relevant concentrations of teriflunomide on activation and proliferation of primary rodent microglia. |
| Q41823791 | Leflunomide inhibits transendothelial migration of peripheral blood mononuclear cells. |
| Q28274721 | Leflunomide: friend or foe for systemic lupus erythematosus? |
| Q34310272 | Molecular mechanisms of glucocorticoid action in rheumatic autoimmune diseases |
| Q37662413 | Perioperative management of immunosuppression in rheumatic diseases--what to do? |
| Q35048399 | Plant alkaloid tetrandrine downregulates IkappaBalpha kinases-IkappaBalpha-NF-kappaB signaling pathway in human peripheral blood T cell |
| Q43591934 | Preliminary study on the immunologic background of good clinical outcome in rheumatoid arthritis patients after one month therapy with leflunomide. |
| Q46954587 | Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates |
| Q47875442 | Protective effects of leflunomide against ischemia-reperfusion injury of the rat liver |
| Q46116237 | Protective effects of leflunomide on intestinal ischemia-reperfusion injury: leflunomide against intestinal ischemia-reperfusion |
| Q51705716 | Recombinant IL-33 prolongs leflunomide-mediated graft survival by reducing IFN-γ and expanding CD4(+)Foxp3(+) T cells in concordant heart transplantation. |
| Q35287485 | SPA0355, a thiourea analogue, inhibits inflammatory responses and joint destruction in fibroblast-like synoviocytes and mice with collagen-induced arthritis |
| Q35953478 | Safety and efficacy of leflunomide in primary Sjögren's syndrome: a phase II pilot study. |
| Q38117110 | Safety, tolerability, and efficacy of oral therapies for relapsing-remitting multiple sclerosis |
| Q44489040 | Suppressive effect of combination treatment of leflunomide and methotrexate on chemokine expression in patients with rheumatoid arthritis. |
| Q34613489 | Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis |
| Q37340103 | Teriflunomide |
| Q24800491 | The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes |
| Q24816880 | The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function |
| Q46034054 | The effects of PDTC plus leflunomide and cyclosporine on the NF-kappaB signaling pathway in mouse-to-rat cardiac xenografts. |
| Q95637970 | The immunology of COVID-19: is immune modulation an option for treatment? |
| Q92131178 | The protective and pathogenic roles of IL-17 in viral infections: friend or foe? |
| Q36352913 | Therapies for rheumatoid arthritis: hope springs eternal |
| Q34731092 | Therapy of systemic lupus erythematosus: a look into the future |
| Q64070333 | Xenogeneic Transplantation of Human Placenta-Derived Mesenchymal Stem Cells Alleviates Renal Injury and Reduces Inflammation in a Mouse Model of Lupus Nephritis |
Search more.