Mutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats

scientific article published on 01 October 2000

Mutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/1098-2744(200010)29:2<87::AID-MC5>3.0.CO;2-R
P698PubMed publication ID11074605

P2093author name stringY Sasaki
Y Konishi
M Tsutsumi
T Tsujiuchi
P2860cites workMADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinomaQ24315119
Mad-related genes in the humanQ24328786
TGF-β signalling from cell membrane to nucleus through SMAD proteinsQ28131770
Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridineQ28368405
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1Q29616726
Somatic alterations of the SMAD-2 gene in human colorectal cancersQ36115083
Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growthQ37378595
TGFbeta signaling: receptors, transducers, and Mad proteins.Q41010880
A human Mad protein acting as a BMP-regulated transcriptional activatorQ41192122
Intracellular signalling: the mad way to do it.Q41238186
SMADs: mediators and regulators of TGF-β signalingQ41732765
Nomenclature: vertebrate mediators of TGFbeta family signalsQ48058869
Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genesQ50754394
Overexpression of midkine in lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats and its increase with progressionQ53424879
Infrequent mutations of the transforming growth factor beta-type II receptor gene at chromosome 3p22 in human lung cancers with chromosome 3p deletionsQ53443601
Molecular analysis of mutations induced by ethylating N-nitroso compounds in the lacI gene of Escherichia coli.Q54587122
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancersQ71167724
Expression of vascular endothelial growth factor and its receptors during lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine in ratsQ77748134
P433issue2
P921main subjectadenocarcinomaQ356033
P304page(s)87-91
P577publication date2000-10-01
P1433published inMolecular CarcinogenesisQ15724597
P1476titleMutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats
P478volume29

Reverse relations

cites work (P2860)
Q43516654Absence of PTEN/MMAC1 gene mutations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats
Q31927242Alterations of the transforming growth factor-beta signaling pathway in hepatocellular carcinomas induced endogenously and exogenously in rats
Q30750539Elevated expression of transforming growth factor βs and the tumor necrosis factor family in lung adenocarcinomas inducedby N-nitrosobis(2-hydroxypropyl)amine in rats
Q43829376FHIT alterations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats
Q26774851Mammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic research
Q39704418No Mutations of Lysophosphatidic Acid Receptor Genes in Lung Adenocarcinomas Induced by N-Nitrosobis(2-hydroxypropyl)amine in Rats

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