Expression and characterization of a recombinant novel reverse transcriptase of a porcine endogenous retrovirus

scientific article published on 01 March 2003

Expression and characterization of a recombinant novel reverse transcriptase of a porcine endogenous retrovirus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0042-6822(02)00131-9
P698PubMed publication ID12667803

P2093author name stringAmnon Hizi
Orna Avidan
Ralf R Tönjes
Shoshana Loya
Ziv Sevilya
P2860cites workTesting anti–HIV drugs in the FIV modelQ71803216
The ribonuclease H activity of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2 is affected by the thumb subdomain of the small protein subunitsQ74449092
Porcine endogenous retroviruses (PERVs): generation of specific antibodies, development of an immunoperoxidase assay (IPA) and inhibition by AZTQ77334533
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl proteinQ27670506
Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding siteQ27730949
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptaseQ27732211
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolutionQ27766103
Establishment and characterization of molecular clones of porcine endogenous retroviruses replicating on human cellsQ30855704
Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutantsQ33554232
Susceptibility of the porcine endogenous retrovirus to reverse transcriptase and protease inhibitorsQ33835882
Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.Q34315598
Infection of human cells by an endogenous retrovirus of pigsQ34418546
Will the pig solve the transplantation backlog?Q34511486
Three-dimensional structure of ribonuclease H from E. coliQ34566873
Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptaseQ34577497
Unique progressive cleavage mechanism of HIV reverse transcriptase RNase HQ35360809
RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-templateQ36098739
Fidelity mechanisms in DNA replicationQ37285267
Strand displacement synthesis of the long terminal repeats by HIV reverse transcriptaseQ38362535
Endogenous retroviruses: a potential problem for xenotransplantation?Q39493013
Extended analysis of the in vitro tropism of porcine endogenous retrovirusQ39588491
The processivity of DNA synthesis exhibited by drug-resistant variants of human immunodeficiency virus type-1 reverse transcriptaseQ39723479
On the processivity of polymerasesQ40707346
Metal binding and activation of the ribonuclease H domain from moloney murine leukemia virusQ41705586
Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase.Q42615638
Reverse transcriptase of mouse mammary tumour virus: expression in bacteria, purification and biochemical characterizationQ42989176
The role of phenylalanine-119 of the reverse transcriptase of mouse mammary tumour virus in DNA synthesis, ribose selection and drug resistanceQ43002250
Insertion of a peptide from MuLV RT into the connection subdomain of HIV-1 RT results in a functionally active chimeric enzyme in monomeric conformationQ43804442
Catalytic features of the recombinant reverse transcriptase of bovine leukemia virus expressed in bacteriaQ44125492
Mutational analysis of the DNA polymerase and ribonuclease H activities of human immunodeficiency virus type 2 reverse transcriptase expressed in escherichia coliQ45301935
The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virusQ45733749
DNA synthesis exhibited by the reverse transcriptase of mouse mammary tumor virus: processivity and fidelity of misinsertion and mispair extensionQ45751245
Folding the ribonuclease H domain of Moloney murine leukemia virus reverse transcriptase requires metal binding or a short N-terminal extensionQ45753777
An enzymatically active chimeric HIV-1 reverse transcriptase (RT) with the RNase-H domain of murine leukemia virus RT exists as a monomerQ45756777
The fidelity of 3' misinsertion and mispair extension during DNA synthesis exhibited by two drug-resistant mutants of the reverse transcriptase of human immunodeficiency virus type 1 with Leu74-->Val and Glu89-->GlyQ45761333
Mutational studies of human immunodeficiency virus type 1 reverse transcriptase: the involvement of residues 183 and 184 in the fidelity of DNA synthesisQ45768857
Fidelity of DNA synthesis exhibited in vitro by the reverse transcriptase of the lentivirus equine infectious anemia virusQ45786836
The fidelity of the reverse transcriptases of human immunodeficiency viruses and murine leukemia virus, exhibited by the mispair extension frequencies, is sequence dependent and enzyme relatedQ45787031
The catalytic properties of the reverse transcriptase of the lentivirus equine infectious anemia virusQ45790014
Expression in Escherichia coli of a Moloney murine leukemia virus reverse transcriptase whose structure closely resembles the viral enzymeQ45847547
Fidelity of the RNA-dependent DNA synthesis exhibited by the reverse transcriptases of human immunodeficiency virus types 1 and 2 and of murine leukemia virus: mispair extension frequenciesQ45872557
Two sets of human-tropic pig retrovirusQ48044130
XenotransplantationQ56777177
P433issue2
P304page(s)341-357
P577publication date2003-03-01
P1476titleExpression and characterization of a recombinant novel reverse transcriptase of a porcine endogenous retrovirus
P478volume307

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cites work (P2860)
Q35914341A Novel Leu92 Mutant of HIV-1 Reverse Transcriptase with a Selective Deficiency in Strand Transfer Causes a Loss of Viral Replication
Q80380272Expression and characterization of a novel reverse transcriptase of the LTR retrotransposon Tf1
Q45399462Expression and characterization of the integrase of bovine immunodeficiency virus
Q36661707Human endogenous retrovirus (HERV-K) reverse transcriptase as a breast cancer prognostic marker
Q37945186Mutation rates and intrinsic fidelity of retroviral reverse transcriptases.
Q30935484Recombinant human antibodies against the reverse transcriptase of human immunodeficiency virus type-1.
Q34559569Reverse transcriptases can clamp together nucleic acids strands with two complementary bases at their 3′-termini for initiating DNA synthesis
Q45417399The catalytic properties of the recombinant reverse transcriptase of bovine immunodeficiency virus
Q34667561The dUTPase-related gene of bovine immunodeficiency virus is critical for viral replication, despite the lack of dUTPase activity of the encoded protein
Q45723106The mature reverse transcriptase molecules in virions of mouse mammary tumor virus possess protease-derived sequences
Q36023065The removal of RNA primers from DNA synthesized by the reverse transcriptase of the retrotransposon Tf1 is stimulated by Tf1 integrase
Q28756733The reverse transcriptase of the Tf1 retrotransposon has a specific novel activity for generating the RNA self-primer that is functional in cDNA synthesis