Dynorphin-(1-8) inhibits the release of substance P-like immunoreactivity in the spinal cord of rats following a noxious mechanical stimulus

scientific article published on 01 April 1997

Dynorphin-(1-8) inhibits the release of substance P-like immunoreactivity in the spinal cord of rats following a noxious mechanical stimulus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-2999(97)00038-1
P698PubMed publication ID9128834

P2093author name stringB D Goldstein
V Zachariou
P2860cites workStimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situQ69084852
Segmental release of Met-enkephalin-like material from the spinal cord of rats, elicited by noxious thermal stimuliQ69597427
Noxious mechanical stimuli increase the release of Met-enkephalin-like material heterosegmentally in the rat spinal cordQ69781810
Effects of neonatal capsaicin treatment on nociceptive thresholds in the ratQ72553372
Antinociceptive profile of dynorphin in the ratQ72571990
Intrathecal substance P elicits a caudally-directed biting and scratching behavior in miceQ72640892
In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesiaQ37484009
Kappa-opioid receptors and analgesiaQ37874600
Blockade of U50,488H analgesia by antisense oligodeoxynucleotides to a kappa-opioid receptorQ38310421
Spinal opiate analgesia: Characteristics and principles of actionQ40128120
Substance P: Depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neuronsQ40229378
Neurotransmitter functions of mammalian tachykininsQ40486282
Effects of substance P on functionally identified units in cat spinal cordQ44184726
Kappa-/mu-receptor interactions in the opioid control of the in vivo release of substance P-like material from the rat spinal cordQ44330612
Long term kappa-opioid receptor blockade following nor-binaltorphimineQ44331653
Kappa-opioid receptor modulation of the release of substance P in the dorsal hornQ44342095
Delta-Opioid receptor modulation of the release of substance P-like immunoreactivity in the dorsal horn of the rat following mechanical or thermal noxious stimulationQ44344151
Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding.Q44345363
Kappa opioid receptors in human lumbo-sacral spinal cordQ44346797
Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neuronsQ44350659
Spinal dynorphin A (1-17): possible mediator of antianalgesic actionQ44797694
Release of substance P into the superficial dorsal horn following nociceptive activation of the hindpaw of the ratQ48607741
Dynorphin1–8 and dynorphin1–9 are ligands for the κ-subtype of opiate receptorQ48898826
Sufentanil, Morphine, Met-enkephalin, and k-Agonist (U-50,488H) Inhibit Substance P Release from Primary Sensory NeuronsQ57241175
Noxious heating of the skin releases immunoreactive substance P in the substantia gelatinosa of the cat: a study with antibody microprobesQ68987784
Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the catQ69078129
P433issue2-3
P407language of work or nameEnglishQ1860
P304page(s)159-165
P577publication date1997-04-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleDynorphin-(1-8) inhibits the release of substance P-like immunoreactivity in the spinal cord of rats following a noxious mechanical stimulus
P478volume323

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cites work (P2860)
Q39387051Analgesia induced by dietary restriction is mediated by the kappa-opioid system.
Q36977191C2 spinal cord stimulation induces dynorphin release from rat T4 spinal cord: potential modulation of myocardial ischemia-sensitive neurons
Q44864213Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception
Q28215587DREAM is a critical transcriptional repressor for pain modulation
Q44349884Mechanisms of μ-opioid receptor inhibition of NMDA receptor-induced substance P release in the rat spinal cord
Q35205479Microdialysis in pain research
Q37256582Molecular bases of caloric restriction regulation of neuronal synaptic plasticity.
Q37553194Nociceptive behavior induced by the endogenous opioid peptides dynorphins in uninjured mice: evidence with intrathecal N-ethylmaleimide inhibiting dynorphin degradation

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