Differential control of the hyperpolarization-activated current (i(f)) by cAMP gating and phosphatase inhibition in rabbit sino-atrial node myocytes

scientific article published on 01 May 1997

Differential control of the hyperpolarization-activated current (i(f)) by cAMP gating and phosphatase inhibition in rabbit sino-atrial node myocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JPHYSIOL.1997.SP022049
P698PubMed publication ID9161982

P2093author name stringD DiFrancesco
G Redaelli
E A Accili
P2860cites workPhosphatase inhibition by calyculin A increases i(f) in canine Purkinje fibers and myocytesQ72964047
Canadian Physiological Society 28th winter meeting. Lake Louise, Alberta, January 24-28, 1996. AbstractsQ73178813
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.Q34580492
Muscarinic activation of ionic currents measured by a new whole-cell recording methodQ36434152
A model of cardiac electrical activity incorporating ionic pumps and concentration changesQ38383023
Effects of protein kinase inhibitors on canine Purkinje fibre pacemaker depolarization and the pacemaker current i(f)Q41149915
The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytesQ41183437
Mode of action of chronotropic agents in cardiac Purkinje fibers. Does epinephrine act by directly modifying the external surface charge?Q41512377
How does adrenaline accelerate the heart?Q41645115
Acetylcholine reverses effects of beta-agonists on pacemaker current in canine cardiac Purkinje fibers but has no direct action. A difference between primary and secondary pacemakersQ41954423
Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.Q42500841
Cyclic AMP mediates the effects of adrenaline on cardiac purkinje fibres.Q43499025
Inhibition of the hyperpolarization-activated current (if) induced by acetylcholine in rabbit sino-atrial node myocytesQ44214225
Biochemical and electrophysiological mechanisms of the positive inotropic effect of calyculin A, a protein phosphatase inhibitor.Q46239338
Effects of the phosphatase inhibitor calyculin A on the phosphorylation of C-protein in mammalian ventricular cardiomyocytesQ46614801
Direct myocardial effects of halothane and isoflurane. Comparison between adult and infant rabbits.Q51625227
Developmental changes in the rabbit sinus node action potential and its response to adrenergic agonists.Q52265088
Properties of the hyperpolarizing-activated current (if) in cells isolated from the rabbit sino-atrial nodeQ57980198
Characterization of single pacemaker channels in cardiac sino-atrial node cellsQ59076073
Activation of the hyperpolarization-activated current (if) in sino-atrial node myocytes of the rabbit by vasoactive intestinal peptideQ70990172
Modulation of single hyperpolarization-activated channels (i(f)) by cAMP in the rabbit sino-atrial nodeQ71629968
Phosphatase inhibitors potentiate adrenergic-stimulated cAMP and cGMP production in rat pinealocytesQ71683257
Pacemaker current i(f) in adult canine cardiac ventricular myocytesQ71709019
Actions of vasoactive intestinal peptide and neuropeptide Y on the pacemaker current in canine Purkinje fibersQ72657940
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)643-651
P577publication date1997-05-01
P1433published inJournal of PhysiologyQ7743612
P1476titleDifferential control of the hyperpolarization-activated current (i(f)) by cAMP gating and phosphatase inhibition in rabbit sino-atrial node myocytes
P478volume500 ( Pt 3)

Reverse relations

cites work (P2860)
Q37240734Age-dependent differences in the inhibition of HCN2 current in rat ventricular myocytes by the tyrosine kinase inhibitor erbstatin
Q37372389Cholinergic receptor signaling modulates spontaneous firing of sinoatrial nodal cells via integrated effects on PKA-dependent Ca(2+) cycling and I(KACh).
Q92734142Comparing pathways for long-term heart rate modulation by the funny current
Q38546747Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia: role of the If "funny" current.
Q36452785Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine
Q38738342Direct inhibition of the pacemaker (If) current in rabbit sinoatrial node cells by genistein.
Q63321134Effect of 5-HT4 receptor stimulation on the pacemaker current If in human isolated atrial myocytes
Q44049291Functional characterisation and subcellular localisation of HCN1 channels in rabbit retinal rod photoreceptors.
Q30757352Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes
Q33710653Hormonal control of cardiac ion channels and transporters
Q33349609How is the heart rate regulated in the sinoatrial node? Another piece to the puzzle
Q40046024Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells.
Q42047413Inhibition by genistein of the hyperpolarization-activated cation current in porcine sino-atrial node cells
Q36923796Mechanisms that match ATP supply to demand in cardiac pacemaker cells during high ATP demand
Q26771350Mechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channels
Q42080710Modeling the chronotropic effect of isoprenaline on rabbit sinoatrial node
Q83844867Muscarinic-activated potassium current mediates the negative chronotropic effect of pilocarpine on the rabbit sinoatrial node
Q42454411Pacemaker channels in mouse thalamocortical neurones are regulated by distinct pathways of cAMP synthesis
Q36339192Pharmacogenetics and cardiac ion channels
Q36012074Regulation of recombinant and native hyperpolarization-activated cation channels.
Q45023548Regulation of the hyperpolarization-activated cationic current Ih in mouse hippocampal pyramidal neurones by vitronectin, a component of extracellular matrix
Q37547401The cardiac pacemaker current
Q39582050Tissue-specific N terminus of the HCN4 channel affects channel activation

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