Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons

scientific article published on 01 May 2000

Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.20-10-03864.2000
P932PMC publication ID6772693
P698PubMed publication ID10804226

P2093author name stringS R Sesack
D B Carr
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Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental areaQ48469772
Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental areaQ48495452
Do non-dopaminergic neurons in the ventral tegmental area play a role in the responses elicited in A10 dopaminergic neurons by electrical stimulation of the prefrontal cortex?Q48508989
Extracellular dopamine and neurotensin in rat prefrontal cortex in vivo: effects of median forebrain bundle stimulation frequency, stimulation pattern, and dopamine autoreceptorsQ48661645
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The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat.Q50933545
Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors.Q51604125
Increased dopamine and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: effects of diazepam.Q51612019
P433issue10
P304page(s)3864-3873
P577publication date2000-05-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleProjections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons
P478volume20

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Q30666934Prefrontal neurons and the genetics of schizophrenia
Q34285610Prefrontal/accumbal catecholamine system processes high motivational salience
Q42113217Presynaptic inhibition of glutamate transmission by α2 receptors in the VTA
Q44374758Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in an NMDA, AMPA/kainate, and metabotropic glutamate receptor-dependent manner.
Q46899798Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement
Q84618031Projections of the medial orbital and ventral orbital cortex in the rat
Q44347866Prolonged effects of repeated social defeat stress on mRNA expression and function of mu-opioid receptors in the ventral tegmental area of rats
Q34297880Prominent activation of brainstem and pallidal afferents of the ventral tegmental area by cocaine
Q34441382Protracted maturation of forebrain afferent connections of the ventral tegmental area in the rat.
Q34616133Psychomotor stimulant addiction: a neural systems perspective.
Q36144909Psychostimulants affect dopamine transmission through both dopamine transporter-dependent and independent mechanisms
Q43115257Pyramidal neurons in rat prefrontal cortex projecting to ventral tegmental area and dorsal raphe nucleus express 5-HT2A receptors
Q35994913Quantitative unit classification of ventral tegmental area neurons in vivo
Q39016315Ramping single unit activity in the medial prefrontal cortex and ventral striatum reflects the onset of waiting but not imminent impulsive actions
Q33957624Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia
Q42586003Reduction in Ventral Midbrain NMDA Receptors Reveals Two Opposite Modulatory Roles for Glutamate on Reward
Q37185815Region-specific changes in the subcellular distribution of AMPA receptor GluR1 subunit in the rat ventral tegmental area after acute or chronic morphine administration
Q42525373Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors
Q36337926Regulation of α4β2α5 nicotinic acetylcholinergic receptors in rat cerebral cortex in early and late adolescence: Sex differences in response to chronic nicotine
Q34060104Relationship between impulsivity, prefrontal anticipatory activation, and striatal dopamine release during rewarded task performance
Q30450143Relationship of Dopamine of the Nucleus Accumbens with Intra-infralimbic Apomorphine Microinjection
Q58612970Relative Contributions and Mapping of Ventral Tegmental Area Dopamine and GABA Neurons by Projection Target in the Rat
Q44126383Repetitive transcranial magnetic stimulation increases the release of dopamine in the mesolimbic and mesostriatal system
Q94550971Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine
Q39280413Resilience to amphetamine in mouse models of netrin-1 haploinsufficiency: role of mesocortical dopamine.
Q34338643Reward and aversion in a heterogeneous midbrain dopamine system.
Q42665192Reward circuitry activation by noxious thermal stimuli
Q37219431Reward circuitry is perturbed in the absence of the serotonin transporter
Q34173418Reward, addiction, withdrawal to nicotine
Q44950469Rewarding effects of AMPA administration into the supramammillary or posterior hypothalamic nuclei but not the ventral tegmental area.
Q47110650Risk of punishment influences discrete and coordinated encoding of reward-guided actions by prefrontal cortex and VTA neurons
Q24658346Role of lateral hypothalamic orexin neurons in reward processing and addiction
Q30474245Role of netrin-1 in the organization and function of the mesocorticolimbic dopamine system
Q40084832Role of the bed nucleus of the stria terminalis in the control of ventral tegmental area dopamine neurons
Q35120472Role of the ventral tegmental area in methamphetamine extinction: AMPA receptor-mediated neuroplasticity
Q53430499SB-334867 (an Orexin-1 Receptor Antagonist) Effects on Morphine-Induced Sensitization in Mice-a View on Receptor Mechanisms.
Q47549477Schizophrenia-Like Dopamine Release Abnormalities in a Mouse Model of NMDA Receptor Hypofunction.
Q38957531Seeing through the smoke: Human and animal studies of cannabis use and endocannabinoid signalling in corticolimbic networks.
Q35087608Sensitized activation of Fos and brain-derived neurotrophic factor in the medial prefrontal cortex and ventral tegmental area accompanies behavioral sensitization to amphetamine
Q48154341Separate mesocortical and mesolimbic pathways encode effort and reward learning signals
Q36778507Serotonin modulation of cortical neurons and networks
Q44705380Sexual behavior and sex-associated environmental cues activate the mesolimbic system in male rats.
Q48245461Simultaneous projections from prefrontal cortex to dopaminergic and serotonergic nuclei
Q21203943Single dose of morphine produced a prolonged effect on dopamine neuron activities
Q48451535Stimulation of D2 receptors in the prefrontal cortex reduces PCP-induced hyperactivity, acetylcholine release and dopamine metabolism in the nucleus accumbens
Q42319408Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release
Q34635329Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders
Q38219966Subcircuit-specific neuromodulation in the prefrontal cortex
Q34557518Substantia nigra activity level predicts trial-to-trial adjustments in cognitive control.
Q44257147Sulpiride alleviates the attentional impairments of rats with medial prefrontal cortex lesions
Q22337221Synaptic plasticity and addiction
Q46832195Task-related interaction between basal ganglia and cortical dopamine release.
Q37656924The Dopamine Prediction Error: Contributions to Associative Models of Reward Learning
Q64236227The Involvement of Intra-Hippocampal Dopamine Receptors in the Conditioned Place Preference Induced By Orexin Administration into the Rat Ventral Tegmental Area
Q88363437The Medial Prefrontal Cortex Shapes Dopamine Reward Prediction Errors under State Uncertainty
Q46506812The absence of 5-HT(1A) receptors has minor effects on dopamine but not serotonin release evoked by MK-801 in mice prefrontal cortex.
Q27024180The comorbidity of insomnia, chronic pain, and depression: dopamine as a putative mechanism
Q28585219The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning
Q30493971The default-mode, ego-functions and free-energy: a neurobiological account of Freudian ideas
Q39431132The dopamine hypothesis of drug addiction and its potential therapeutic value
Q36083476The dopamine hypothesis of drug addiction: hypodopaminergic state.
Q36756361The dopamine system and the pathophysiology of schizophrenia: a basic science perspective
Q48630966The effects of a single exposure to uncontrollable stress on the subsequent conditioned place preference responses to oxycodone, cocaine, and ethanol in rats
Q38783826The exercise-glucocorticoid paradox: How exercise is beneficial to cognition, mood, and the brain while increasing glucocorticoid levels.
Q40615369The inhibitory influence of the lateral habenula on midbrain dopamine cells: ultrastructural evidence for indirect mediation via the rostromedial mesopontine tegmental nucleus
Q37346217The lateral mesopontine tegmentum regulates both tonic and phasic activity of VTA dopamine neurons
Q36088209The laterodorsal tegmentum contributes to behavioral sensitization to amphetamine
Q33874287The limbic circuitry underlying cocaine seeking encompasses the PPTg/LDT.
Q41980721The medial prefrontal and orbitofrontal cortices differentially regulate dopamine system function
Q37123077The medial prefrontal cortex regulates the differential expression of morphine-conditioned place preference following a single exposure to controllable or uncontrollable stress
Q38048764The neurobiology of opiate motivation
Q37342815The neurokinin-3 (NK3) and the neurokinin-1 (NK1) receptors are differentially targeted to mesocortical and mesolimbic projection neurons and to neuronal nuclei in the rat ventral tegmental area
Q48388262The orexin-1 receptor antagonist SB-334867 blocks the effects of antipsychotics on the activity of A9 and A10 dopamine neurons: implications for antipsychotic therapy
Q58793943The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study
Q91130303The relationship between grey matter volume and striatal dopamine function in psychosis: a multimodal 18F-DOPA PET and voxel-based morphometry study
Q26852620The role of neuromodulators in selective attention
Q28217710The significance of action potential bursting in the brain reward circuit
Q34340909The therapeutic role of 5-HT1A and 5-HT2A receptors in depression
Q46076764The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?
Q37907986The vertebrate mesolimbic reward system and social behavior network: a comparative synthesis.
Q34590409There and back again: a tale of norepinephrine and drug addiction
Q38728024Time-dependent effects of prazosin on the development of methamphetamine conditioned hyperactivity and context-specific sensitization in mice
Q43884117Toluene inhalation produces regionally specific changes in extracellular dopamine
Q48137874Top-down-directed synchrony from medial frontal cortex to nucleus accumbens during reward anticipation
Q27005054Turning a Negative into a Positive: Ascending GABAergic Control of Cortical Activation and Arousal
Q42130383Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells
Q38338668Understanding opioid reward
Q50535284Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia.
Q38990044Unravelling the Link Between Prenatal Stress, Dopamine and Substance Use Disorder
Q92187727VTA GABA Neurons at the Interface of Stress and Reward
Q39067598Ventral tegmental area: cellular heterogeneity, connectivity and behaviour
Q47615008Verification of a genetic locus for methamphetamine intake and the impact of morphine.
Q39335378Viral strategies for targeting cortical circuits that control cocaine-taking and cocaine-seeking in rodents
Q39160294Viral vector strategies for investigating midbrain dopamine circuits underlying motivated behaviors
Q34037180Viral-mediated expression of extracellular signal-regulated kinase-2 in the ventral tegmental area modulates behavioral responses to cocaine
Q37309789Volatile solvents as drugs of abuse: focus on the cortico-mesolimbic circuitry
Q43182540When desire collides with reason: functional interactions between anteroventral prefrontal cortex and nucleus accumbens underlie the human ability to resist impulsive desires
Q28475974rTMS of the left dorsolateral prefrontal cortex modulates dopamine release in the ipsilateral anterior cingulate cortex and orbitofrontal cortex

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