scholarly article | Q13442814 |
P356 | DOI | 10.1034/J.1600-0854.2001.002006385.X |
P698 | PubMed publication ID | 11389766 |
P50 | author | Terence Tao | Q102141031 |
P2093 | author name string | A M Tartakoff | |
P2860 | cites work | The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription | Q22254119 |
Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals | Q24310136 | ||
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons | Q24317574 | ||
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood | Q24614744 | ||
Intracellular localization of the P21rho proteins | Q24642838 | ||
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. | Q27937925 | ||
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease | Q28114818 | ||
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation | Q28246858 | ||
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract | Q28267110 | ||
Roles for proteolysis and trafficking in notch maturation and signal transduction | Q28281399 | ||
Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes | Q28291798 | ||
Distinction of apoptotic and necrotic cell death by in situ labelling of fragmented DNA | Q28306970 | ||
Life without huntingtin: normal differentiation into functional neurons | Q28590704 | ||
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice | Q29615357 | ||
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain | Q29617982 | ||
Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA | Q29620175 | ||
Localization of rabbit huntingtin using a new panel of monoclonal antibodies | Q30640638 | ||
Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells | Q30779186 | ||
Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease | Q33703899 | ||
Regulation of nuclear localization: a key to a door | Q33804320 | ||
Reversing neurodegeneration: a promise unfolds | Q33897927 | ||
Review: dynamic stability of the interphase nucleus in health and disease | Q33915698 | ||
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies | Q33920421 | ||
Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases | Q34133850 | ||
Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor | Q34973238 | ||
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation | Q35195588 | ||
Identification of two lysosomal membrane glycoproteins | Q36212360 | ||
Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation | Q36255989 | ||
Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation | Q36823776 | ||
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. | Q40858681 | ||
Analysis of the subcellular localization of huntingtin with a set of rabbit polyclonal antibodies in cultured mammalian cells of neuronal origin: comparison with the distribution of huntingtin in Huntington's disease autopsy brain | Q40859417 | ||
Wild-type huntingtin protects from apoptosis upstream of caspase-3. | Q40880907 | ||
Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells. | Q40916040 | ||
Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin. | Q40949615 | ||
In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease. | Q40981007 | ||
Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line | Q41000432 | ||
A cellular model that recapitulates major pathogenic steps of Huntington's disease | Q41017315 | ||
The influence of huntingtin protein size on nuclear localization and cellular toxicity. | Q41035353 | ||
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract | Q41182414 | ||
Heat shock proteins increase resistance to apoptosis. | Q41226590 | ||
The identification of a functional nuclear localization signal in the Huntington disease protein | Q41285600 | ||
Transcriptional activation modulated by homopolymeric glutamine and proline stretches | Q41488003 | ||
Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila | Q41705884 | ||
A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response | Q41711854 | ||
Cytoplasmic localization and the choice of ligand determine aggregate formation by androgen receptor with amplified polyglutamine stretch | Q41860888 | ||
Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein | Q42598739 | ||
Huntington's disease gene product, huntingtin, associates with microtubules in vitro | Q45295496 | ||
Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine. | Q45296134 | ||
Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length | Q45296163 | ||
Huntingtin: a single bait hooks many species | Q45296265 | ||
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA. | Q45296558 | ||
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin | Q45297223 | ||
Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. | Q45297497 | ||
Formation of polyglutamine inclusions in non-CNS tissue | Q45298039 | ||
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. | Q45298582 | ||
Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors | Q45299117 | ||
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease | Q45300376 | ||
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy. | Q45301281 | ||
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila | Q47945602 | ||
Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition. | Q48298684 | ||
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. | Q48373564 | ||
Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice | Q48373570 | ||
Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse | Q48574817 | ||
Inhibition of drug-induced apoptosis by survival factors in PC12 cells | Q72557651 | ||
Expression of extended polyglutamine sequentially activates initiator and effector caspases | Q77341954 | ||
Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin | Q77906721 | ||
P433 | issue | 6 | |
P304 | page(s) | 385-394 | |
P577 | publication date | 2001-06-01 | |
P1433 | published in | Traffic | Q1572846 |
P1476 | title | Nuclear relocation of normal huntingtin | |
P478 | volume | 2 |
Q59799803 | A discontinuous Galerkin model for fluorescence loss in photobleaching of intracellular polyglutamine protein aggregates |
Q36647206 | An N-terminal nuclear export signal regulates trafficking and aggregation of Huntingtin (Htt) protein exon 1. |
Q30425063 | Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice |
Q35867566 | Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD. |
Q40717667 | Huntingtin is required for ciliogenesis and neurogenesis during early Xenopus development |
Q24294765 | Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis |
Q33826159 | Huntingtin localisation studies - a technical review |
Q57839949 | Huntingtin proteolysis in Huntington disease |
Q30480364 | Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease |
Q34145515 | Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization |
Q28247421 | Interaction between importin 13 and myopodin suggests a nuclear import pathway for myopodin |
Q52102715 | Nucleocytoplasmic shuttling of lgl2 is developmentally regulated in fetal lung. |
Q35575850 | Role of proteolysis in polyglutamine disorders |
Q36597920 | Selective neuronal degeneration in Huntington's disease |
Q41154714 | The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal |
Q37339087 | The roles of multiple importins for nuclear import of murine aristaless-related homeobox protein |
Q36003871 | The roles of proteolysis and nuclear localisation in the toxicity of the polyglutamine diseases. A review |
Search more.