| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M910191199 |
| P698 | PubMed publication ID | 10887199 |
| P2093 | author name string | Liu J | |
| Nakanishi K | |||
| Itagaki Y | |||
| Sparrow JR | |||
| Ben-Shabat S | |||
| P2860 | cites work | A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy | Q24324625 |
| Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease | Q28138732 | ||
| Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice | Q28140171 | ||
| Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration | Q28248752 | ||
| Influence of early photoreceptor degeneration on lipofuscin in the retinal pigment epithelium | Q28609969 | ||
| Lipid to Protein Chromophore Transfer in the Photolysis of Visual Pigments | Q28609981 | ||
| Characterization of phospholipase D activity in bovine photoreceptor membranes | Q28610019 | ||
| Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium | Q28610021 | ||
| Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration | Q31906407 | ||
| Inherited retinal dystrophy in the rat. | Q36185157 | ||
| Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus. | Q40674593 | ||
| Lipofuscin fluorophore inhibits lysosomal protein degradation and may cause early stages of macular degeneration | Q41121335 | ||
| Total Synthesis of the Ocular Age Pigment A2-E: A Convergent Pathway | Q57903202 | ||
| Ocular Age Pigment “A2-E”: An Unprecedented Pyridinium Bisretinoid | Q57903209 | ||
| Retinal age pigments generated by self-assembling lysosomotropic detergents | Q59071585 | ||
| Lipofuscin autofluorescence: evidence for vitamin A involvement in the retina | Q69154822 | ||
| Phospholipids of bovine outer segments | Q71672725 | ||
| Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction | Q72773568 | ||
| Morphologic changes in age-related maculopathy | Q73028696 | ||
| Formation of lipofuscin-like fluorophores by reaction of retinal with photoreceptor outer segments and liposomes | Q73175950 | ||
| P433 | issue | 38 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 7 | |
| P304 | page(s) | 29354-29360 | |
| P577 | publication date | 2000-09-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane | |
| P478 | volume | 275 |
| Q36923756 | 11-cis- and all-trans-retinols can activate rod opsin: rational design of the visual cycle |
| Q34721084 | A novel form of transducin-dependent retinal degeneration: accelerated retinal degeneration in the absence of rod transducin |
| Q41555677 | A2E and lipofuscin distributions in macaque retinal pigment epithelium are similar to human |
| Q28609934 | A2E, a byproduct of the visual cycle |
| Q50091811 | A2E-associated cell death and inflammation in retinal pigmented epithelial cells from human induced pluripotent stem cells |
| Q45070126 | Absolute configurational determination of an all-trans-retinal dimer isolated from photoreceptor outer segments |
| Q80080068 | Accumulation of A2-E in mitochondrial membranes of cultured RPE cells |
| Q49476807 | All-trans retinal levels and formation of lipofuscin precursors after bleaching in rod photoreceptors from wild type and Abca4-/- mice |
| Q33920123 | Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration |
| Q82910578 | Autofluorescence and optical coherence tomography findings in optic disc pit-associated maculopathy: case series |
| Q41531438 | Biochemical Measurements of Free Opsin in Macular Degeneration Eyes: Examining the 11-CIS Retinal Deficiency Hypothesis of Delayed Dark Adaptation (An American Ophthalmological Society Thesis). |
| Q35107574 | Biogenesis and cellular dynamics of aminoglycerophospholipids |
| Q37691648 | Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype |
| Q64093353 | Blue Autofluorescence Fundus Imaging for Monitoring Retinal Degeneration in Royal College of Surgeons Rats |
| Q36917117 | Characterization of dihydro-A2PE: an intermediate in the A2E biosynthetic pathway |
| Q36182294 | Clinicopathologic findings in Best vitelliform macular dystrophy |
| Q37729439 | Comparison of autofluorescence and optical coherence tomography findings in acute and chronic central serous chorioretinopathy |
| Q35133725 | Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium |
| Q92132455 | Comprehensive expression patterns of inflammatory cytokines in aqueous humor of patients with neovascular age-related macular degeneration |
| Q89446142 | Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome |
| Q34272304 | Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina |
| Q90520564 | Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina |
| Q36225789 | Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epithelium |
| Q36591612 | Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents |
| Q37114451 | Early changes in gene expression induced by blue light irradiation of A2E-laden retinal pigment epithelial cells. |
| Q33899116 | Effects of organic solvents on two retinal pigment epithelial lipofuscin fluorophores, A2E and all-trans-retinal dimer |
| Q37438794 | Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin |
| Q33956569 | Enzymatic degradation of A2E, a retinal pigment epithelial lipofuscin bisretinoid |
| Q34997806 | Experimental approaches to the study of A2E, a bisretinoid lipofuscin chromophore of retinal pigment epithelium |
| Q30490714 | FUNDUS AUTOFLUORESCENCE LIFETIMES AND CENTRAL SEROUS CHORIORETINOPATHY. |
| Q34076309 | Fluorescence lifetime measurements and biological imaging |
| Q34286193 | Fluorescent pigments of the retinal pigment epithelium and age-related macular degeneration |
| Q50504065 | Foveal sparing in patients with Japanese Stargardt's disease and good visual acuity. |
| Q24657568 | Functional roles of bestrophins in ocular epithelia |
| Q35174717 | Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular Degeneration |
| Q33331882 | Fundus autofluorescence after full macular translocation surgery for myopic choroidal neovascularization. |
| Q33809041 | Fundus autofluorescence and the bisretinoids of retina |
| Q37343605 | G1961E mutant allele in the Stargardt disease gene ABCA4 causes bull's eye maculopathy |
| Q35894518 | Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells |
| Q34268770 | High resolution MALDI imaging mass spectrometry of retinal tissue lipids |
| Q92524765 | High-Resolution Adaptive Optics in Vivo Autofluorescence Imaging in Stargardt Disease |
| Q42535902 | How much blue light should an IOL transmit? |
| Q37388770 | Identification of a novel lipofuscin pigment (iisoA2E) in retina and its effects in the retinal pigment epithelial cells |
| Q33297465 | Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells |
| Q34199909 | Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. |
| Q41953801 | Interaction of A2E with model membranes. Implications to the pathogenesis of age-related macular degeneration. |
| Q60916938 | Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration |
| Q34135516 | Interpretations of fundus autofluorescence from studies of the bisretinoids of the retina |
| Q37149680 | Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli |
| Q52568656 | Iron promotes oxidative cell death caused by bisretinoids of retina. |
| Q33821589 | Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate |
| Q90650301 | Isopropyl-phloroglucinol-DHA protects outer retinal cells against lethal dose of all-trans-retinal |
| Q34814102 | Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium |
| Q57184443 | Light-induced generation and toxicity of docosahexaenoate-derived oxidation products in retinal pigmented epithelial cells |
| Q36839855 | Lipofuscin and A2E accumulate with age in the retinal pigment epithelium of Nrl-/- mice |
| Q36052545 | Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal |
| Q36290158 | Lipofuscin-associated photo-oxidative stress during fundus autofluorescence imaging |
| Q64055368 | Low-Luminance Blue Light-Enhanced Phototoxicity in A2E-Laden RPE Cell Cultures and Rats |
| Q34452853 | Mass spectrometry provides accurate and sensitive quantitation of A2E |
| Q37155498 | Melanoregulin (MREG) modulates lysosome function in pigment epithelial cells |
| Q34483182 | Multi-modality imaging on multiple evanescent white dot syndrome-A Spectralis Study |
| Q92602858 | Multicolor imaging in central serous chorioretinopathy - a quantitative and qualitative comparison with fundus autofluorescence |
| Q37101460 | New insights into retinoid metabolism and cycling within the retina |
| Q25255844 | Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye |
| Q89480128 | Novel bisretinoids of human retina are lyso alkyl ether glycerophosphoethanolamine-bearing A2PE species |
| Q37339031 | Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease |
| Q30395134 | PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage |
| Q99710877 | Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells |
| Q33577803 | Phospholipid meets all-trans-retinal: the making of RPE bisretinoids |
| Q37040750 | Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration |
| Q33732517 | Photooxidation of RPE lipofuscin bisretinoids enhances fluorescence intensity. |
| Q36104068 | Photoreaction, phototoxicity, and photocarcinogenicity of retinoids |
| Q48507644 | Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence |
| Q30843751 | Quantifying Fundus Autofluorescence in Patients With Retinitis Pigmentosa |
| Q38819731 | Quantitative metabolomics of photoreceptor degeneration and the effects of stem cell-derived retinal pigment epithelium transplantation |
| Q46373713 | Quercetin and cyanidin-3-glucoside protect against photooxidation and photodegradation of A2E in retinal pigment epithelial cells |
| Q93095010 | RETINAL FLECKS IN STARGARDT DISEASE REVEAL CHARACTERISTIC FLUORESCENCE LIFETIME TRANSITION OVER TIME |
| Q34454034 | Rapid formation of all-trans retinol after bleaching in frog and mouse rod photoreceptor outer segments |
| Q35830670 | Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage |
| Q36179752 | Retinal photodamage mediated by all-trans-retinal |
| Q34463809 | Retinal photodamage. |
| Q24646826 | Retinopathy in mice induced by disrupted all-trans-retinal clearance |
| Q35027607 | Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylation |
| Q24537573 | Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. |
| Q37415751 | Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E. |
| Q34967125 | Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium. |
| Q33831456 | Spatial localization of A2E in the retinal pigment epithelium |
| Q34988214 | Stress reaction in outer segments of photoreceptors after blue light irradiation |
| Q37172298 | Structures and biogenetic analysis of lipofuscin bis-retinoids |
| Q36861483 | The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells |
| Q36288534 | The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model. |
| Q35785390 | The bisretinoids of retinal pigment epithelium |
| Q33598084 | The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry |
| Q34955566 | Therapy for macular degeneration: insights from acne |
| Q35868411 | Transgenic Mice Overexpressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration through a Retinoid-Independent Mechanism |
| Q28547211 | Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity |
| Q35189371 | Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases |
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